Term
|
Definition
|
|
Term
|
Definition
| Hflu (includes factor V, NAD+ and factor X, hematin) |
|
|
Term
| Charcoal yeast culture (iron and cysteine) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
1. metronidazole, bismuth, tetracyclin OR amoxicillin
2. metronidazole, omeprazole, clarithromycin |
|
|
Term
|
Definition
|
|
Term
| VDRL positive NOT syphilis |
|
Definition
| treponema pertenue - causes yaws |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| francisella tularensis (tularemia) |
|
|
Term
|
Definition
| the plague - yersinia pestis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Rickettsiae - treat with tetracyclins |
|
|
Term
|
Definition
| serum from pts with rickettsial infection will react with proteus antigens and agglutinate (except coxiella or Q fever) |
|
|
Term
| tumbling motility (microbe) |
|
Definition
|
|
Term
|
Definition
| taenia solium (cysticercosis) |
|
|
Term
|
Definition
|
|
Term
SCC of bladder (microbe)
treatment? |
|
Definition
schistosoma haematobium
praziquantel |
|
|
Term
|
Definition
|
|
Term
|
Definition
HSV infected Cell
[image] |
|
|
Term
[image]
Councilman Bodies |
|
Definition
Yellow Fever or viral hepatitis - inclusion body seen in liver
[image][image] |
|
|
Term
|
Definition
Paramyxoviruses
(Parainfluenza, Rubeola, RSV, Mumps)
Mediates cell entry
targeted by pavilizumab |
|
|
Term
|
Definition
Negri Bodies
Rabies infected neurons |
|
|
Term
[image]
Sulfur granules + Branching rods from oral sample |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Whipple's Disease - Tropheryma whippelii |
|
|
Term
| fungal infection in pt with DM |
|
Definition
|
|
Term
|
Definition
|
|
Term
| High titer of IgM (cold agglutinins) |
|
Definition
|
|
Term
| Mississippi and Ohio River valleys |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| budding yeast w/ captain's wheel appearance (circle with spokes coming out) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| spaghetti and meatball on KOH |
|
Definition
|
|
Term
|
Definition
|
|
Term
| brain "soap bubble" lesion |
|
Definition
|
|
Term
| non-septate hyphae w/ wide angles |
|
Definition
|
|
Term
|
Definition
Pneumocystis jiroveci (PCP)
Stain lung tissue |
|
|
Term
|
Definition
|
|
Term
| Neonate w/ chorioretinitis, intracranial calcifications, hydrocephalus |
|
Definition
|
|
Term
| rapid meningoencephalitis post swim in fresh water? |
|
Definition
|
|
Term
|
Definition
| trypanosoma gambiense or rhodesiense - sleeping sickness |
|
|
Term
| Treatment - trypanosoma gambiense or rhodesiense |
|
Definition
| suramin, melarsoprol (if CNS penetration needed) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Treatment - Leishmania donovani |
|
Definition
|
|
Term
| Treatment - Plasmodium vivax/ovale |
|
Definition
| choloroquine plus primaquine for dormant liver bugs |
|
|
Term
|
Definition
|
|
Term
| treatment - enterobius vermicularis |
|
Definition
| bendazoles or pyrantel pamoate |
|
|
Term
| treatment - ascaris lumbricoides |
|
Definition
| bendazoles or pyrantel pamoate |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| treatment - strongyloides stercoralis |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Treatment - river blindness |
|
Definition
|
|
Term
|
Definition
| mebendazole (bendazoles) or pyrantel palmoate |
|
|
Term
| treatment - dracuculus medinensis |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Elephantiasis - infectious agent and treatment |
|
Definition
| wuchereria bancrofti, diethycarbamazine |
|
|
Term
| Treatment - toxocara canis |
|
Definition
|
|
Term
|
Definition
| taenia solium, praziquantel (bendazoles for neurocysticercosis) |
|
|
Term
| Ate freshwater fish, now anemic from B12 deficiency? Treatment? |
|
Definition
| Diphyllobothrium latum, praziquantel |
|
|
Term
Liver cyst - surgeon injects ethanol before removal
treatment? |
|
Definition
echinococcus granulosus
bendazoles |
|
|
Term
gallstones after eating undercooked fish?
Treatment? |
|
Definition
clonorchis sinensis
praziquantel |
|
|
Term
Hemoptysis after eating crab?
Treatment? |
|
Definition
Paragonimus westermani
Praziquantel |
|
|
Term
| infectious agent causing microcytic anemia? |
|
Definition
| hookworm (ancylostoma duodenale, necator americanus) via sucking blood from intestinal walls |
|
|
Term
| Live vaccine given to HIV+ patients |
|
Definition
|
|
Term
|
Definition
| Herpes (HSV 1&2, EBV, CMV, VZV), HBV, smallpox |
|
|
Term
|
Definition
|
|
Term
|
Definition
| reoviruses (rotavirus, reovirus - colorado tick fever) |
|
|
Term
|
Definition
| Adenovirus, papilomaviruses, parvovirus |
|
|
Term
| RNA enveloped viruses (10) |
|
Definition
| Influenza, parainfluenza, RSV, measles, mumps, rubella, rabies, HTLV, HIV, HCV |
|
|
Term
|
Definition
| enteroviruses (polio, coxsackie, echovirus, HAV, HEV), rhinovirus, reovirus (rotavirus) |
|
|
Term
| infectious agent seen within neutrophils |
|
Definition
|
|
Term
| cellulitis post ocean (or lake) swim? |
|
Definition
| aeromonas and vibrio vulnificans |
|
|
Term
|
Definition
| serum mixed with cardiolipin, cholesterol and lecithin. Test for spirochet antibodies |
|
|
Term
|
Definition
| Pseudomonas, vibrio cholera, campylobacter |
|
|
Term
| osteomyelitis in patient with sickle cell anemia? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Babesia (left - ring form, right - maltese cross) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| envelope from nuclear membrane |
|
Definition
| Herpes viruses (HSV 1&2, EBV, CMV, VZV, Roseola, HHV8) |
|
|
Term
|
Definition
|
|
Term
|
Definition
hemagglutinin (viral entry)
neuraminidase (progeny virion release) |
|
|
Term
| UTI assoc with struvite stones |
|
Definition
|
|
Term
| Rash head -> toes, postauricular lymphadenopathy |
|
Definition
|
|
Term
| angiomatosis in immunocompromised individuals - confused with karposi sarcoma |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| staph (aureus, saprophyticus, epidermidis), nocardia, serratia, pseudomonas cepacia, Aspergillus |
|
|
Term
| Inhibit peptidoglycan cross-linkin |
|
Definition
| penicillin, ampicillin, ticarcillin, pipercillin, imipenem, aztroenam, cephalosporins |
|
|
Term
| Inhibit peptidoglycan synthesis |
|
Definition
|
|
Term
| inhibits 50S peptidyltransferase |
|
Definition
|
|
Term
| inhibit initiation complex formation (30S) |
|
Definition
|
|
Term
| bind 50S blocking translocation |
|
Definition
| macrolides (erythromycin), clindamycin, lincomycin |
|
|
Term
|
Definition
|
|
Term
| Block protein synth at 30S ribosomal subunit |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Block nucleotide synthesis |
|
Definition
| Sulfonamides, trimethoprim (SMX-TMP) |
|
|
Term
| Bacteriostatic antibiotics |
|
Definition
| Erythromycin, clindamycin, SMX, TMP, tetracyclins, chloramphenicol |
|
|
Term
|
Definition
| vancomycin, fluoroquinolones, penicillin, aminoglycosides, cephalosporins, metronidazole |
|
|
Term
| Sensitive to ampicilling/amoxicillin |
|
Definition
| Hflu, Ecoli, listeria, proteus, salmonella, enterocci |
|
|
Term
|
Definition
inhibits cell wall synth, resistent to beta-lactamases
treats gram negative rods
no cross allergenicity with penicillins |
|
|
Term
| Pt needs imipenem, what else do you give? |
|
Definition
| Cilastatin (decrease inactivation of renal tubules by inhibiting renal dihydropeptidase I) |
|
|
Term
| mechanism of resistance to Vanc? |
|
Definition
| via amino acid change of D-ala D-ala to D-ala D-lac. |
|
|
Term
|
Definition
| inhibit cell wall mucopeptide formation by binding to D-ala D-ala of cell wall precursers |
|
|
Term
|
Definition
|
|
Term
| Antibiotic, requiring O2 for uptake |
|
Definition
|
|
Term
| Ototox with loop diaretics |
|
Definition
|
|
Term
| nephrotox with aminoglycosides |
|
Definition
|
|
Term
| Tetracylines - dietary restrictions |
|
Definition
| milk, iron-containing products, antiacids (divalent cations inhibit gut absorption) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| macrolides (esp erythromycin) |
|
|
Term
|
Definition
| cholamphenicol (due to lack of UDP-glucuronyl transferase) |
|
|
Term
| Antibiotic with side effect of aplastic anemia |
|
Definition
|
|
Term
|
Definition
| PABA antimetabolites inhibit dihydropteroate synthetase (ie formation of tetrahydrofolic acid needed for thymine, purine and methionine, glycine and tRNA synth) |
|
|
Term
|
Definition
| Inhibits dihydrofolate reductase (inhibits THF- tetrahydro folic acid - formation) |
|
|
Term
| displaces warfarin from albumin |
|
Definition
|
|
Term
| side effect - granulocytopenia and leukopenia |
|
Definition
|
|
Term
| produces orange body fluids |
|
Definition
|
|
Term
| prevent neurotox with isoniazid |
|
Definition
|
|
Term
| Drug causing optic neuropathy |
|
Definition
|
|
Term
|
Definition
| decreased synthesis of mycolic acids |
|
|
Term
| Tetracycline resistance mechanism |
|
Definition
| increased transport out or decreased uptake |
|
|
Term
| MRSA resistance mechanism |
|
Definition
|
|
Term
| Aminoglycoside resistance |
|
Definition
| acetylation, adenylation or phosphorylation |
|
|
Term
| chloramphenicol resistance mechanism |
|
Definition
|
|
Term
| Macrolide resistance mechanism |
|
Definition
| methylation of rRNA near ribosome binding site |
|
|
Term
| fluoroquinolones resistance mechanism |
|
Definition
| altered gyrase or reduced uptake |
|
|
Term
| sulfonamide resistance mechanism |
|
Definition
| altered enzyme (dihyropteroate synthetase), decreased uptake or increased PABA synthesis |
|
|
Term
|
Definition
|
|
Term
|
Definition
| lanosterol to ergosterol inhibition |
|
|
Term
|
Definition
| squalene to lanosterol inhibition |
|
|
Term
| amphotericin and nystatin mechanism |
|
Definition
| pore formation, disrupting membrane |
|
|
Term
| antifungal that crosses blood-brain barrier |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Torch infections - rubella |
|
Definition
| PDA (or pulmonary artery hypoplasia), cataracts, deafness, blueberry muffin rash, microcephaly/MR |
|
|
Term
| latex particle agglutination test |
|
Definition
|
|
Term
| cryptococcus treatment in HIV+ patients |
|
Definition
| amphotericin B and flucytosine |
|
|
Term
|
Definition
Lipid A
Induces shock by macrophage and granulocyte activation |
|
|
Term
|
Definition
| uropathogenic or enteropathogenic Ecoli, cholera, pertussis, neisseria meningitidis |
|
|
Term
|
Definition
| cryptococcus, stains polysaccaride capsule |
|
|
Term
| Make dextrans from glucose |
|
Definition
|
|
Term
| chronic abscess after dental trauma |
|
Definition
|
|
Term
|
Definition
| N. meningitidis, gateway to CSN invasion |
|
|
Term
| Waterhouse-Friedrich syndrome |
|
Definition
| bilateral adrenal cortex hemorrhage causes adrenal insufficiency, hypotension, death |
|
|
Term
|
Definition
| pharynges-lymphatics-meninges |
|
|
Term
| Guillain Barre after diarrheal illness |
|
Definition
|
|
Term
| Bacteria that produce hyaluronidase |
|
Definition
| Group A Streptococci, C. Difficile, staph |
|
|
Term
|
Definition
mycoside found in TB, causes to grow "serpentine" on culture
Virulence factor that inactivates neutrophils, damages mitochondria and induces TNF release |
|
|
Term
| Pts serum agglutinates sheep erythocytes, indicating presence of heterophil antibodies |
|
Definition
| positive monospot test pt has mono (EBV) |
|
|
Term
|
Definition
| staph - impair complement mediated cell lysis. Binds to Fc portion of IgG more than bacterial surface antigen |
|
|
Term
| Increase intracellular survival by inhibition of phagosome-lysosome fusion |
|
Definition
| TB, M.laprae, legionella, ehrlichia |
|
|
Term
| opsonization impairment mechanism of bacteria |
|
Definition
capsule formation - poorly immunogenic polysaccarides.
S. Pneumo, N. meningitidis, H. flu, Crypto |
|
|
Term
|
Definition
cleaves IgA dimers, inhibiting mucus membrane immunity
N. gonorrhoeae, N. Meningitidis |
|
|
Term
|
Definition
capsule on Ecoli seen in neonatal meningitis.
Inhibits complement and phagocytosis |
|
|
Term
| intracellular polyphosphate granules |
|
Definition
| diptheria, seen w/ methylene blue staining |
|
|
Term
Ring-enhancing lesions in HIV patient
Treatment? |
|
Definition
Toxo
treat - pyrimethamine and sulfadiazine |
|
|
Term
| skin layer break allowing for infection |
|
Definition
|
|
Term
|
Definition
| hydrocephalus, intracanial calcifications, chorioretinitis |
|
|
