Term
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Definition
| Bacterial or viral transplant molecules that elicit an immune response |
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Term
| What are 2 types of specific defenses? |
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Definition
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Term
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Definition
| Phagocytes, macrophages and neutrophils that activate T cells |
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Term
| Describe Humoral response |
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Definition
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Term
| What are some natural barriers? |
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Definition
| Physiological and chemical |
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Term
| Describe Acquired (adaptive) active natural |
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Definition
| Naturally developing a response (flu) |
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Term
| Describe Acquired (adaptive) active artificial |
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Definition
-Immunizations
-Subcellular fragments
-toxins |
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Term
| Describe Acquired (adaptive) passive artificial |
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Definition
-Monoclonal Abs
-Snake toxins
-Immune cells
-injection of someone else's Abs |
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Term
| Describe Acquired natural passive |
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Definition
| transfer of immunoglobulins to fetus colostral transfer of IgA |
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Term
| Name and describe 3 types of Acute inflammation |
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Definition
| Vasculature: Pain, warmth, swelling, vasodilation Cellular: Monocytes, Macrophages, Neutrophils Humoral: Complement, cytokines, chemokines |
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Term
| Name the Ab source and Indication for: Diptheria |
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Definition
| Human/Horse prophylaxis: immunodeficiencies |
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Term
| Name the Ab source and Indication for: varicella |
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Definition
| Human: Immunodeficiencies |
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Term
| Name the Ab source and Indication for: gas gangrene, botulism, snake bite, scorpion sting |
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Definition
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Term
| Name the Ab source and Indication for: rabies |
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Definition
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Term
| Name the Ab source and Indication for: hypogammaglobulinemia |
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Definition
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Term
| Name an adaptive advantage of passive immunization |
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Definition
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Term
| Name disadvantages of passive immunization |
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Definition
-short term
-aids/ hep
-GVHD
-serum sickness |
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Term
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Definition
| Severe combine immunodeficiency -enzyme deficiency means Ab sites are abnormal since certain cells are unable to produce binding sites -results in early morbidity since patients cant produce Abs |
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Term
| Define 3 inherited cellular immunodeficiency disorders |
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Definition
-T cell (Di george)Thymus does not develop
-B cell (Brutons) Enzyme def where no IgG is made and lack Ab development
-Phagocytic (Chediak-Higashi) prevents neutrophils from phagocytizing bc of enzyme deficiency (inherited) |
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Term
| Define 1 inherited Humoral immunodeficiency disorders |
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Definition
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Term
| Define hyperacute rejection and give 3 sensitizing events |
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Definition
-Preformed Ab againist HLA
-Pregnancy, blood transfusion, previous transplant |
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Term
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Definition
| HLA sensitization and HLA specific Ab/T cells are generated bc of foreign material - immune response doesn't do what its supposed to |
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Term
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Definition
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Term
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Definition
-can generate immune cells that are againist the host
-replacing diseased bone marrow with new bone marrow |
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Term
| What organ does not require a match? |
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Definition
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Term
| What's reduced immunogenecity? |
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Definition
| you are unable to mount a response or are not as effective at doing so |
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Term
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Definition
tumor associated antigens- new/altered Ag - similar to viral infections
-defective signaling from tumor cells to activate T cells to kill but dont since they cant activate T cells effectively |
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Term
| What type of immunity results from recovery of the mumps |
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Definition
| Natural acquired active immunity |
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Term
| What type of immunity results from immunizations |
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Definition
| Artifical acquired active immunity |
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Term
| Newborns' immunity due to the transfer of Ab across the plasma membrane is what type of immunity? |
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Definition
| Natural acquired passive immunity |
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Term
| Sensitization in relationship to transplantation means... |
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Definition
| immediate rejection of the transplant |
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