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Microbiology Exam 4
Chapter 22
36
Microbiology
Undergraduate 2
03/17/2012

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Cards

Term
What are examples of upper respiratory tract infections?
Definition
Streptococcal pharyngitis
Diptheria
Pertussis
Ottitis media
The common cold
Term
What is the function of the nasal mucosa?
Definition
-Warms and humidifies air
-Catches airborne microorganisms
-Swells when irritated
Term
What is the mucosa of the upper respiratory tract lined with?
Definition
Ciliary epithelium
Term
What type of cells produce mucous?
Definition
Goblet cells
Term
Describe the mucociliary escalator,
Definition
Cilia sweep the mucous to the pharynx, where it is swallowed
Term
Name the sterile structures of the upper respiratory tract.
Definition
Tear ducts
Sinuses
Middle ear
Airway from trachea down
Term
What is the normal flora of the anterior nares?
Definition
Staphylococci
Term
What is the normal flora of the nasopharynx?
Definition
Viridans streptococci, Moraxella spp., haemophilus spp., Neisseria spp.
Term
What is the normal flora of the oral cavity?
Definition
Anaerobes, streptococci
Term
Where does normal flora stop?
Definition
About the level of the larynx
Term
What is one of the most common infections in children?
Definition
Streptococcal pharyngitis
Term
What strain of streptococcal pharyngitis causes 15-30% of all cases?
Definition
S.pyogenes
Term
True or False: A child can become a carrier if streptococcal protein F adheres to human fibronectin
Definition
True
Term
Describe the pathogenesis of Streptococcus pyogenes
Definition
Invades the pharynx and causes inflammation
Term
The erythrogenic toxin of streptococcal pharyngitis causes what?
Definition
Scarlet fever
Term
What are the signs and symptoms of Streptococcal pharyngitis?
Definition
Pain, fever, difficulty swallowing, erythema, petechial hemorrhaging, enlarged tonsils (adenoids) sometimes pus
Term
What are the signs and symptoms of viral pharyngitis?
Definition
Cough and rhinitis
Term
When do poststreptococcal sequellae occur?
Definition
Weeks or months after the infection
Term
What is the result of rheumatic fever causes by strep?
Definition
In some cases, permanent valve damage
Term
How is streptococcal pharyngitis diagnosed?
Definition
Throat swab with rapid antigen test and culture
Term
What is the drug that is used to treat streptococcal pharyngitis?
Definition
Penicillin, macrolibes are alternative but resistance is increasing
Term
True or False: Treatment does not change the course of infection, but prevents spread of sequellae
Definition
True
Term
What does Corynebacterium diphtheriae produce?
Definition
Diphtheria exotoxin
Term
The toxin of diphtheria causes damage to what organs?
Definition
The heart and kidneys
Term
What does Bordetella pertussis produce and cause?
Definition
Produces several toxins
Causes tracheolaryngitis, "whooping cough" in children
Term
What is Bordetella pertussis treated with?
Definition
Macrolides
Term
Describe the epidemiology of Otitis media?
Definition
-Very common, in 3/4 of children under 2
-Closely follows viral colds
-Kids grow out of them as their head grows
Term
Describe the pathogenesis of Otitis media.
Definition
-Never a primary disease; starts when something closes the eusachian tube (cold, allergy, smoke)
-Can start with mixed flora, usually end up with Streptococcus pneumoniaw or Haemophilus influenzae
Term
How is Otitis media diagnosed?
Definition
Usually clinically; redness and bulging of the eardrum
Sometimes the drum can rupture or be aspirated to get culture material (tympanocentesis)
Term
Describe initial treatment
Definition
Nothing; can give decongestants
Term
Describe treatment if severe
Definition
Antibiotics-usually amoxicillin, Augementin (amoxicillin/clavulanate) or Pediazole (erythromycin/sulfa)
Term
Describe treatment if recurrent
Definition
Drainage tubes to allow the ear to drain and dry
Term
Describe the epidemiology of the common cold
Definition
Extremely common; 2-5 per year
Spread by direct contact
Term
What are the signs and symptoms of the common cold?
Definition
Sore throat, rhinitis, cough, hoarseness
Term
Where does the common cold virus enter?
Definition
The eyes, nose or mouth
Term
Describe the signs and symptoms of Adenovirus pharyngitis
Definition
Pharyngitis, rhinitis, low fever, enlarged lymph nodes
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