Term
| True or false? Typical bacterial pneumonia has an insidious onset |
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Definition
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Term
| What is the most common cause of pneumonia? |
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Definition
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Term
| This causitive agent of pneumonia often affects alcoholics |
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Definition
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Term
| In a inconclusive gram stain and sputum/blood investigation what would be the next step? |
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Definition
| Legionella urinary antigen, and serology for M Pneumoniae and Chlamydophila pnuemoniae |
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Term
| Empirical treatment of pneumonia commonly involves what two classes of antibiotics? |
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Definition
| Macrolides and cephalosporins |
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Term
| What are the morphological characteristics of Strep Pneumoniae? |
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Definition
| Gram-positive, lancet-shaped diplococci |
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Term
| Is Strep Pneumoniae alpha or beta hemolytic? catalase negative or positive? Optochin resistant or sensitive? |
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Definition
| Alpha hemolytic, catalase negative and optochin sensitive |
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Term
| What factors can increase spread of S Pneumoniae? |
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Definition
| Crowded conditions, concomitant or prior viral respiratory infection, AIDS, asplenia, influenza, sickle cell, multiple myeloma, alcoholism, smoking, diabetes, hypogammaglobinemia, nephrotic syndrome |
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Term
| What is the sequence of pathogensis of S pneumoniae infection? |
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Definition
| upper airway colonization, aspiration of a large bacterial inoculum, failure of host defenses to clear the inoculum, bacterial proliferation, inflamation in lung |
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Term
| What Immunoglobulin and complement proteins are most important for the opsonization of S Pneumoniae in the lung? |
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Definition
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