Term
|
Definition
| Long slender helically-curved gram-negative bacilli |
|
|
Term
| Which 3 genera are pathogenic? |
|
Definition
| Treponema (medium coils), Borrelia (loose coils), leptospira (tight coils) |
|
|
Term
|
Definition
| normal oral/genital flora, obligate human organism |
|
|
Term
| T. pallidum subspecies pallidum |
|
Definition
|
|
Term
| T. pallidum subspecies pertenue |
|
Definition
|
|
Term
| T. pallidum subspecies endemicum |
|
Definition
|
|
Term
|
Definition
| chancre (painless ulcer at site of inoculation) |
|
|
Term
|
Definition
| fever, headache, lymphadenopathy, rash, 25% recurrence rate |
|
|
Term
| tertiary syphilis (latent) |
|
Definition
| no clinical manifestations, tissue destructive lesions (CNS, cardiovascular, eye), not contagious |
|
|
Term
|
Definition
| miscarriage/stillbirth, early in pregnancy- cutaneous lesions, CNS damage, late in pregnancy- bone damage, eye lesions, pointed teeth |
|
|
Term
| Laboratory diagnosis of Syphilis |
|
Definition
| DarkField Micropscopy, and serological tests |
|
|
Term
| DarkField Micropscopy of syphilis |
|
Definition
| characteristic flexing and bending motility |
|
|
Term
| serological test (screening) for syphilis |
|
Definition
| flocculation using reagin as antigen, VDRL, or RPR, therapy should decrease titers |
|
|
Term
| serological test (confirmatory) for syphilis |
|
Definition
| antigen, fluorescent treponemal antibody absorption, microhemagglutination test for T. pallidum, once you’re positive, you stay positive for life |
|
|
Term
|
Definition
| stains with Giemsa, causes relapsing fever |
|
|
Term
|
Definition
|
|
Term
|
Definition
| B. hermsii, B. turicatae, B. parkeri |
|
|
Term
|
Definition
| 4-10 days of fever, headache and myalgia |
|
|
Term
| diagnosis of relapsing fever |
|
Definition
| direct observation of motility in blood wet preps, Giemsa stained slides or serology |
|
|
Term
|
Definition
| Borrelia burgdorferi, transmitted by ixodes ticks |
|
|
Term
|
Definition
| erythema migrans, fever, headache, muscle and joint pain, bulls-eye rash |
|
|
Term
|
Definition
| meningitis, neurologic deficits, carditis |
|
|
Term
|
Definition
| chronic arthritis (being re-infected) |
|
|
Term
| Diagnosis of Lyme disease |
|
Definition
| IFA, ELISA, western blot, molecular methods (test the tick) |
|
|
Term
|
Definition
| hooked ends, 180 serovars |
|
|
Term
|
Definition
| transmitted by contact with urine or blood of infected animals |
|
|
Term
|
Definition
| fever, headache, myalgia, more severe liver, kidney, vascular dysfunction |
|
|
Term
| Diagnosis of Weil's Disease |
|
Definition
| dark field microscopy on blood, urine or CSF, culture in semisolid media enriched with rabbit serum or serology studies |
|
|
Term
| Cell wall deficient bacteria |
|
Definition
| no cell wall, small, requires sterols for growth, aerobic and fastidious, resistant to penicillin |
|
|
Term
| Names of the Cell wall deficient bacteria |
|
Definition
| Mycoplasma and ureaplasma- some are normal flora |
|
|
Term
|
Definition
| atypical pneumonia (non productive cough), upper respiratory infection in children, lower respiratory infections in adults |
|
|
Term
| M. hominis and U. urealyticum are |
|
Definition
|
|
Term
| genital tract infections of mycoplasma |
|
Definition
| prostatitis, PID, amnionitis, nongonococcal urethritis |
|
|
Term
| immunosupressed patients infected with mycoplasma |
|
Definition
| Bacteremia, arthritis, abscesses and wound infections |
|
|
Term
| congenital infection of mycoplasma |
|
Definition
| meningitis, pneumonia and abscesses. |
|
|
Term
|
Definition
| culture on selective media with different substrates |
|
|
Term
|
Definition
|
|
Term
| Plate morphology of mycoplasma |
|
Definition
|
|
Term
| Mycoplasmas and ureaplasmas are different from other bacteria |
|
Definition
| because they have no cell wall |
|
|
Term
| The clinical significance of mycoplasma pneumonia, M. hominis and ureaplasma urealyticum is |
|
Definition
| they can cause serious infections in healthy, immunosupressed, newborn individuals |
|
|
Term
| Penicillin type antibiotics are not the drug of choice for mycoplasma infections because |
|
Definition
| they are resistant to penicillin |
|
|
Term
| You order a venereal syphilis on an 81 year old patient because |
|
Definition
| because it’s possible that she was infected earlier in life and never got treated, she could have been dormant for awhile and now she has progressed to tertiary stage syphilis which can cause serious CNS damage |
|
|
Term
|
Definition
| you need to order a confirmatory serological test because RPR is just a screening test |
|
|
Term
| The health department should be notified |
|
Definition
| after a positive confirmatory test |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| transmission of Leptospirosis |
|
Definition
| contact with urine or blood of an infected animal |
|
|
Term
| Diagnosis of leptospirosis |
|
Definition
| dark field microscopy on blood, urine or CSF, culture in semisolid media enriched with rabbit serum or serology studies |
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