Term
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Definition
| Borrelia, Plasmodium, trypanosomes, Chlamydia |
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Term
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Definition
| Stains glycogen, mucopolysaccharides; use dto diagnose whipple disease! |
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Term
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Definition
| Stains acid fast bacteria |
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Term
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Definition
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Term
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Definition
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Term
| Culture requirement for H. influenza |
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Definition
| Chocolate agar with factor V and X |
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Term
| Culture requirement for N. gonorrhea |
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Definition
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Term
| Culture requirement for B. pertussis |
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Definition
| Bordet-Gengou (potato) agar |
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Term
| Culture requirement for C. diphtheria |
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Definition
| Tellurite plate, Loeffler's media |
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Term
| Culture requirement for M. tuberculosis |
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Definition
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Term
| Culture requirement for M. pneumonia |
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Definition
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Term
| Culture requirement for E. coli |
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Definition
| EMB agar (blue black colonies with metallic sheen) |
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Term
| Culture requirement for Lactose fermenting enterics |
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Definition
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Term
| Culture requirement for Legionella |
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Definition
| Charcoal yeast extract agar buffered with increased iron and cystein |
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Term
| Culture requirement for Fungi |
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Definition
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Term
| Obligate intracellular bacteria |
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Definition
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Term
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Definition
| Strep pneumo, N. meningitidis, H. influenza, klebsiella pneumonia (some nasties have kapsules) |
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Term
|
Definition
| Proteus, Klebsiella, H. pylori, Ureaplasma (particular kinds have urease) |
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Term
| Staph aureus virulence factor |
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Definition
| Protein A - binds FC portion of Ig thereby disruptin opsonization and phagocytosis |
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Term
| IgA protease (what it does and what organisms have it) |
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Definition
| cleaves IgA and prevents phagocytosis; S. pneumo, H. flu, Neisseria |
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Term
| Group A strep virulence factor |
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Definition
| M protein; helps prevent phagocytosis by inhibiting activation of complement (also antigenic!) |
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Term
| Facultative Intracellular organisms |
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Definition
| Salmonella, Neisseria, Brucella, Mycobacterium, Listeria, Francisella, Legionella, Yersinea (Some nasty bugs may live facultativeLY); inhibit phagosome lysosome fusion! |
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Term
|
Definition
| C. tetani neurotoxin; blocks release of GABA and glycine form inhibitory neurons; uncontrolled muscle contraction with lockjaw and paralysis of respiratory muscles |
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Term
|
Definition
| C. botulinum neurotoxin; inhibits acetycholine release from motro neuron endplates; Flacid paralysis with resp muscle paralysis |
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Term
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Definition
| V. Cholera enterotoxin; A-B toxin; ADP ribosylation of GTP-binding protein -- activates adenylate cyclase -- inc cAMP -- inc NaCl secretion; rice water diarrhea |
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Term
| E. coli Labile toxin (LT) |
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Definition
| similar to cholera toxin; in E. coli, C. jejuni, B. cereus; stimulates adenylate cyclase (labile like the Air) |
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Term
| E. coli stable toxin (ST) |
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Definition
| E. coli, Y. enterocolitica; activates guanylate cyclase to produce GMP -- inhibition of NaCl absorption |
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Term
| Shiga toxin and Shiga-like toxin |
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Definition
| Shigella and E. coli O157:H7; inhibits protein synthesis bu inactivating 60s killing absorptive cells; bloody diarrhea, HUS! |
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Term
|
Definition
| FOOD POISONING; diarrhea and vomitting for less that 24 hrs |
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Term
| B. cereus heat stable toxin |
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Definition
| FOOD POISONING; vomitting less that 24 hrs with limited diarrhea |
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Term
|
Definition
| Group A strep (strep pyogenes); SUPERANTIGEN: activates IL-1 and other sepsis mediators and large numbers of T cells; SCARLET FEVER; COMES FROM BACTERIOPHAGE BY LYSOGENIC CONVERSION |
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Term
|
Definition
| Staph aureus; SUPERANTIGEN; causes toxic shock syndrome (fever, rash, shock) |
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Term
|
Definition
| Hemolysin O and S (lyses RBCs), Streptokinase (lyses fibrin clots), DNAses (hydrolyze DNA); Hyaluronidase (breaks down proteoglycans), NADase; ABscesses, skin infections, systemic infections |
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Term
|
Definition
| Lipases, penicillinases, staphylokinase, leukocidin, exfoliatin (epithelial cell lysis), factors that bind complement; abscesses, skin infections, systemic infection |
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Term
| causes scalded skin syndrome |
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Definition
| exfoliatin (staph aureus) |
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Term
|
Definition
| Alpha toxin: hyfrolyzes licithin in cell membranes causing cell death; tissue destruction and gas gangrene |
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Term
| Bacillus anthracis toxins |
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Definition
| Edema factor (adenylate cyclase--inc cAMP in neuts and macrophages inhibiting ability to phagocytose), protective antigen (allows binding), lethal factor (inactivates protein kinase) |
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Term
|
Definition
| A-B toxin; ribosylates EF and inhibits translation; myocarditis, peripheral nerve palsies, CNS effects; obtains from lysogenic conversion |
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Term
|
Definition
| Increases cAMP by inibiting Galpha1 (inhibitory receptor); also inhibits chemokine receptor causing lymphocytosis; whooping cough |
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Term
|
Definition
| Toxin A: fluid secretion and mucosal inflammation -- diarrhea; Toxin B: cytotoxic to colonic epithelial cells; PSEUDOMEMBRANOUS ENTEROCOLITI |
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Term
|
Definition
| Exotoxin A; inhibits EF2 (same as diphtheria) and inhibits protein synthesis; targets liver |
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Term
|
Definition
| V. cholera (activates Gs); B. pertussis (inactivates Gi); E.coli heat labile toxin; Bacillus anthracis (edema factor is an adenylate cyclase) |
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Term
| Bacterial toxins encoded in lysogenic phage |
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Definition
| ShigA-like toxin, Botulinum toxin, Cholera toxin, Diphtheria toxin, Erythrogenic toxin of strep pyogenes (ABCDE) |
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Term
|
Definition
| Staph: saprophyticus resistant; epidermidis sensitive (NO StRES) |
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Term
|
Definition
| Strep: viridans resistant; pneumonia sensitive (OVRPS) |
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Term
|
Definition
| Strep: Gp B resistant; Gp A sensitive (B-BRAS) |
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Term
|
Definition
| Strep pneumo (optochin sens), Viridans strep (optochin resistant) |
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Term
|
Definition
| S aureus (coagulase pos), Strep pyogenes (GAS- bacitracin sens), Strep agalactiae (GBS - bacitracin resistant),Listeria Monocytogenes (tumbling) |
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Term
| Lactose fermenting bacteria |
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Definition
| Pink on MacConkey; Citrobacter, Klebsiella, E. coli, Enterobacter, Serratia |
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Term
| Things that cause Palm and sole rash |
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Definition
| Coxsackievirus A infection (hand, foot and mouth disease), RMSF, Syphilis (CARS) |
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