Term
|
Definition
|
|
Term
|
Definition
| product microbe makes does the damage |
|
|
Term
|
Definition
| cell lysis and tissue damage |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| some gram+ and - bacteria |
|
|
Term
| all toxins cause damage to host cell through ___ |
|
Definition
| altering physiology of certain tissues |
|
|
Term
| Number of different endotoxins |
|
Definition
|
|
Term
| number of different exotoxins |
|
Definition
|
|
Term
| exotoxins are what kind of macromolecule |
|
Definition
|
|
Term
| How Lipid A is introduced into a cell |
|
Definition
| gram- cell is phagocytized by leukocyte and degraded by lysosome, releasing Lipid A |
|
|
Term
| Lipid A stimulates production and release of ___ |
|
Definition
| interleukin-1 and tumor necrosis factor |
|
|
Term
|
Definition
| resets thermostat of hypothalamus to higher temperature - fever |
|
|
Term
|
Definition
| multiple pathways can damage capillaries and causes fluid loss and disseminated coagulation |
|
|
Term
| ways endotoxins can be lethal |
|
Definition
| shock, disseminate intravascular coagulation, acute respiratory distress syndrome |
|
|
Term
|
Definition
| massive fluid loss results in heart failure |
|
|
Term
| disseminated intravascular coagulation |
|
Definition
| multiple organ failure from damage to multiple capillary beds from clotting |
|
|
Term
| acute respiratory distress syndrome |
|
Definition
| fluid loss in lungs blocks gas exchange |
|
|
Term
| two subunits of exotoxins |
|
Definition
|
|
Term
|
Definition
| binds to specific cell type |
|
|
Term
|
Definition
| changes physiology of cell |
|
|
Term
| general types of exotoxins |
|
Definition
| neurotoxins, enterotoxins, cytotoxins |
|
|
Term
|
Definition
|
|
Term
|
Definition
blocks release of acetylcholine from motor end plates
no muscle fiber depolarization |
|
|
Term
|
Definition
|
|
Term
|
Definition
| binds to large intestine epithelium and activates adenylate cyclase which is synthesized into cyclic AMP (cAMP) |
|
|
Term
|
Definition
alters membrane permeability to reverse osmolarity gradient
draws H20 and ions out of epithelial cells |
|
|
Term
| how botulism causes death |
|
Definition
| flaccid paralysis - death from inability to breath |
|
|
Term
|
Definition
| death from rapid dehydration |
|
|
Term
|
Definition
|
|
Term
| diptheria toxin targets what structures? |
|
Definition
|
|
Term
| diptheria toxin binding site |
|
Definition
| elongation factor and inhibits protein synthesis |
|
|
Term
|
Definition
| necrotic tissue in pharynx dislodging and blocking glottal opening or heart failure |
|
|
Term
|
Definition
| microbial pathogen stimulating an immune response that causes damage |
|
|
Term
| microbe that uses cell lysis |
|
Definition
all lytic viruses
phinovirus, rotavirus |
|
|
Term
| intracellular bacteria examples |
|
Definition
|
|
Term
| common enzyme damaging pathogens |
|
Definition
| staphylococcus and streptococcus |
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