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scientific study of disease
or
diseased or due to a disease |
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| the manner in which a disease originates and develops |
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| the ability of a microorganism to cause disease |
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| deviation from normal structure of function of any part of body manifested by a set of s/s |
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colonization or invasion of body by pathogenic organisms or viral particles
when the balance of normal microbiota is upset, disease can result |
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requires: P.I.R.
1. Pathogen
2. Invasion
3. Reaction
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a microbe is in or on the body do and does not cause reaction.
P.I. |
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1st disease noted in a person's illness
(Usually exogenous) |
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| often an endogenous pathogen that is normal microbiota |
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| Endogenous microbiota may cause disease in an immune-weakened host |
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| Factors which allow for endogenous infections: |
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a. chemical change
b. weakened body defenses
c. circumvent
d. change in virulence |
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Confined to an area
i.e. boils, wart, ringworm |
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agents of a local infection can spread to another specific part of body
i.e. tooth absess to kidney |
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| rapid onset, short duration |
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| long duration, progresses more slowly |
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currently not demonstrating s/s but can later become active
i.e. shingles |
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| new symptoms when latent infection becomes active |
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