Term
| First & second lines of defense |
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Definition
| Innate and nonspecific, always on guard. Do not improve with repeated exposure. Also involves inflammatory and phagocitic defenses |
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Term
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Definition
| All about barriers. Physical (anatomical), chemical, and genetic. Physical: thick skin, cilia, mucus, secretions. Chemical secretions are anything; lysozyme in tears, hcl in stomach, seamen, sweat, skin's ph etc. Genetic; geneticly resistant to something (typically viruses) |
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Term
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Definition
| Inflammation, interferon, phagocytosis, complement defense. |
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Term
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Definition
| Specific, acquired, T cells and B cells. |
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Term
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Definition
| The study of all of the bodies 2nd and 3rd lines of defense. A healthy functioning immune system is responsible for: survellance of the body, recognition of foreign material, destion of entities deemed to be foreign. |
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Term
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Definition
| Is identified by WBC's as they read "markers" on their surfaces, WBC's that ?? |
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Term
| Body compartments and communication |
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Definition
| Reticuloendothelial system (RES), extracellular fluid (ECF), blood stream, lymphatic system |
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Term
| Reticuloendothelial system |
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Definition
| Network of connective tissue fibers that provide a passageway between tissues and organs. Ex: Thymus, lymph nodes and spleen. Has Macrophages (WBC's) |
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Term
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Definition
| Compartmentalized network of vessels cells and specialized acessory organs. Transport lymph through a system of vessels and lymph nodes. Primary functions include; returning ECF to circulatory system proper, act as a drain off system for inflammatory response, render survailence recognition and protection against foreign materials |
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Term
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Definition
| Plasma- like liquid formed wwhen certain blood components move out of blood vessels into the extracellular spaces and diffuse into the lymphatic capilaries. Like plasma but no RBC's. |
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Term
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Definition
| Similar to thin-walled veins, and run along the lines of blood vessels. High numbers in hands, feet, and nipples.Only flows in direction from extremities towards the heart. Lymph is moved by the contraction of skeletal muscles which lymphatic vessels wend their way through. |
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Term
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Definition
| Thymus, spleen, lymoh nodes. |
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Term
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Definition
| Small, encapsulated, bean shaped organs. Usually found in clusters along lymphatic channels and large blood vessels and thoracic and abdominal cavities. Major aggregations: axillary nodes, inguinal nodes, cervical nodes |
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Term
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Definition
| Similar to lymph node but it filters blood instead of lymph. Filters pathogens from blood. |
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Term
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Definition
| Originates in the embryo, high rates of activity and growth until puberty. Shrinks gradually through adulthood. Thymic hormones help thymocytes develop specificity to be released as mature T cells. |
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Term
| Miscellaneous lymphoid tissue |
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Definition
| Tonsils, breasts of lactating women, GALT (gut associated= appendix, lacteals, peyer's patches) MALT (mucosal) SALT (skin) BALT (bronchial) |
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Term
| Circulatory system & blood components |
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Definition
| Consists of circulatory system proper and lymphatic system. Whole blood- blood cells suspended in plasma. Serum- plasma without clotting factors. |
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Term
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Definition
| 92% water, hundreds of chemicals, proteins (albumin & globulins) immunochemicals, fibrogen (& other clotting factors), hormones, nutrients, disolved gases & waste products |
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Term
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Definition
| Precursor stem cell in marrow. Differentiates into stem cells for blood cells and lymphoid cells |
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Term
| Stem cell for blood cells |
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Definition
| Differentiate into; erythroblasts (RBC's), Megakaryoblasts (platelets), myeloblasts (granulocytes & mast cells) monoblasts (monocytes, macrophages & dendrites) |
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Term
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Definition
| Differentiate into lymphoblasts which differentiate into T and B cells. |
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Term
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Definition
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Term
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Definition
| Granulocytes, most common, horse shoe nuclei. Phagocytoses bacteria- granules are digestive enzymes. First to arrive to immune response. |
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Term
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Definition
| In bone marrow and spleen, attach and destroy eukaryotic pathogens, associated with inflammation and allergies. |
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Term
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Definition
| Present in very low numbers in the body. Fuction is sismilar to epsinophils, localized basophils are mast cells, mast cells are important in allergic responses. |
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Term
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Definition
| Specific immunity, 2nd most common in body, AGRANULOCYTES |
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Term
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Definition
| Come out of bone marrow and survive as phagocytes for a few days and then they differentiate into macrophages. |
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Term
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Definition
| Develop from stem cells in the bone marrow, loose nuclei before they get into circulation. Transport oxygen and co2 to and from tissues |
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Term
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Definition
| Fragments of membrane. Formed elements in circulating blood. Function primarily in hemostasis and releasing chemicals for blood clotting and inflammation. |
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Term
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Definition
| Inflammation, interferon, phagocytosis, compliment. Relatively nonspecific but do communicate with 3rd line |
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Term
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Definition
| 2nd line of defense. Classic signs & symptoms; rubor, calor, tumor, dolor & loss of function. Main function is to immune components to the site of injury, set in motion tissue repair & clear away harmful substances. Destroy microbes & block further invasion. |
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