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Micro Biology Unit 2 PCC
Winter Ohten
84
Biochemistry
Graduate
12/03/2010

Additional Biochemistry Flashcards

 


 

Cards

Term
Capsid
Definition
Tight Shell of protein around virus
Term
Enveloped viruses
Definition
Viruses that acquire an outer lipoprotein coat by "budding" through the host cell membranes
Term
DNA Viruses
Definition
messenger RNA is transcribed from viral DNA
Term
RNA viruses
Definition
Cary RNA polymerase, which directs both transcription and replication of RNA genome
Term
Retroviruus
Definition
Reverse Transcriptase
Makes DNA out of RNA
Term
PFU's
Definition
Plaque forming unit
Lyse monolayer (makes hole)
Term
FFU's
Definition
Focus Forming Unit
Similar to a wart
Lose inhibition to growth
Term
Attenuated Vaccines
Definition
Live
Can infect
Both humeral and cellular immunity
Term
Inactivated Vaccine
Definition
Dead
Can't infect
Primarily a humoral response
Term
Influenza A
Definition
further categorized into subtypes
Multiple
Term
Influenza type B
Definition
no subtypes
undergo antigenic drift less rapidly than type A
Human/Pig
Term
Antigenic drift
Definition
results from point mutations
creates new influenza virus variants
Term
Guillain-Barre's Syndrome
Definition
(GBS)
Nerve damage, polio-like paralysis, and coma
Complication of influenza, usually occurs after recovery or immunization
Term
Reye's
Definition
Child complication of Influenza or Chicken Pox
Term
Flu vaccine
Definition
innactive
several strains of A and B
Term
Rhinoviruses
Definition
Picornaviruses
Grow best at 33 degrees C
110 serotypes
Can spread: otitis media, sisusitis, pneumonia
Term
Aerosol
Definition
made way childhood viruses spread
Airborn droplets
Term
Orthomyxoviridae
Definition
Infuenza virus
Term
Picornaviruses
Definition
Rhinoviruses
Term
Coronaviridae
Definition
coranoviruses
Term
Coranavirus
Definition
1/3 of "colds"
SARS occurs when virus encompasses lower respiratory tract
Term
Adenoviruses
Definition
Flu like symptoms
42 human serotypes
Can cause pertussis syndrome (sounds like whooping cough)
Sign: fever, can cause conjunctivitis
May be oncogenic
Enduces obesity in animals
Term
Paramyxovirus
Definition

Respiratory Syncytial virus

Main  cause of infant hospitalization

Term
Respiratory Syncytial Virus
Definition
RSV
Main cause of infant hospitalization
common cause of bronchiolitis and pneumonia
Term
Human Parvovirus B12
Definition
Fifth disease/Erythema Infectiosum/Slap Cheek Disease
Term
Fifth Disease
Definition
Erythema Infectiosum
"Slap Cheek Disease"
Grows in stem cells
Lacy appearance
Can cause Aplastic crisis in people with chronic anemia
Can cause Hydrops Fetalis
Term
Varicella Zoster
Definition
"Chicken Pox"
VZV
Member of Herpesviridae family
Reye's syndrome may occur during recovery
May cross placenta and cause fetal damage
Given as a live vaccine
Term
Herpes Zoster
Definition
"Shingles"
Caused by chickenpox
Virus remians in nerve roots and emerges years later to cause illness
More common after 50
Term
Polio/Poliomyelitis
Definition
Picornaviridae
3 types
Vaccine today is inactive
Term
Brunhilde Strain
Definition
Polio Type 1
Major number of epidemics
Sometimes causes paralysis
Term
Lansing Strain
Definition
Polio Thype II
Occurs Sporatically
Invariably causes paralysis
Term
Leon Strain
Definition
Polio Type III
Usually remains in intestines
Can cause paralysis
Term
Where does the Polio disease strike?
How often does it cause paralysis?
Definition
GI tract
Rarely
Term
Hepatitis A
Definition
Infectious Hepatitis
Caused by ingestion of fecal matter
Can be acquired from shellfish
Term
Serum Hepatitis
Definition
Serum Hepatitis
Caused by contact with infectious blood, semen, and other bodily fluids.
Primarily contracted from sexual contact, birth to infected mother.
Term
Hepatitis C
Definition
Non A/B hepatitis
Most commonly contracted through blood contact.
Can be sexually transmitted
Term
HBV vaccine
Definition
subunit vaccine
contains surface antigen
Term
Hepatitis D
Definition
Serious liver disease
Needs to piggy back on HBV
Term
Viral Gastroenteritis
Definition
common illness
explosive onset of diarrhea, nausea, vomiting, low-grade fever, cramps, headache, and malaise
Term
Reoviridae
Definition

REO= Respiratory Enteric Orphan Enters Oropharynx by age 16 50-80% have Ab to all 3 types

A cause of Viral Gastroenteritis

Term
Rotaviruses
Definition
Common cause HOSPITALIZATION among children.
Vomiting and watery diarrhea for 3-8 days
Term
Enteroviruses
Definition
Picornaviridae family
noroviruses
coxsackie viruses
echovirus
Term
Nuroviruses
Definition
"Norwalk virus"
Common on cruise ships
Term
Coxsackie virus
Definition
Hand Foot Mouth Disease
A and B groups
cause many conditions
Rash on hands, feet, and pharynx
vesicles to ulcers, heal without crusting
Term
Coxsackie A virus
Definition
associated with diseases with vesicular lesions
Term
Coxsackie B Virus
Definition
Most frequently associated with myocarditis and pleurodynia
Term
Echovirus
Definition
ECHO= Enteric Cytopathogenic Human Orphan
Viable in sewage and water.
Term
Arborviruses
Definition
Tree virus, Mosquito-born viruses
West Nile, Dengue fever, Yellow fever
Term
West Nile Virus
Definition
Serious symptoms in 1/150 people that contract it.
Mild flu-like symptoms in 20% that contract it.
No symptoms in 80% that get it.
at least 19 mosquitoes types carry it in US
Term
Dengue Fever
Definition
Caused by any of 4 related dengue viruses
Carried by Aedes mosquitoes
Person can be infected by two, if not all four types in lifetime.
Fever and near full body Rash
Term
Yellow Fever
Definition
Yellow fever virus (flavivirus group)
Aedia aegypti Mosquito spread
20% death rate
Term
Epstein-Barr Virus
Definition
Herpesviridae family
Implicated in:
African Burkitt's Lymphoma
B-cell latency
Infectious mononucleosis
Berkitt's lymphoma
Anaplastic nasopharyngeal carcinoma
B-cell lymphomas
Downey Cells
Term
Downey Cells
Definition
Atypical Lymphocytes
Term
Infectious Mononucleosis
Definition
"Kissing Disease"
spread mouth to mouth, fomites, droplets
No symptoms in children
Epstein Barr is responsible
Term
B cell latency
Definition
EBV infects B cells establishing latent infections
Transformed into immortal, continually dividing cells
Term
Burkitt's Lymphoma
Definition
B-cell lymphoma edemicto Africa and New Guinea
Term
Cytomegalovirus
Definition
Family: Herpesviridae
Virus most frequently transmitted to a developing child before birth. Can cause hearing, mental deficiencies
If aquired after birth there are few symptoms.
Dormant in body for life.
Recurrent disease rarely occurs
Term
Infectious CMV
Definition
Previously infected people intermittently shed in bodily fluids.
Term
Negri Bodies
Definition
Indication of Rabies infection
Term
Rabies
Definition
Rhabdoviridae family
Highest mortality rate of any human disease
Travels up nerve to brain
Term
Herpes Simplex
Definition
Family Herpesviridae
Lipschutz bodies
Worst effects are social/mental
cold sores, genital herpes is toublesome
Term
Neonatal Herpes
Definition
LIfe threatening
Term
Three forms of Herpes
Definition
Cutaneous lesions: confined to skin

Generalized infections: Life threatening. disseminates throughout organs

Encephalitis: (Direct infection of brain tissue, life threatening)
Term
Papillomavirus
Definition
100 different strains
Cause cutaneous warts on skin, and mucosal warts (genital, oral, and conjunctival)
More than 30 STD's
50% of sexually active acquire genital HPV
Term
Mycology
Definition
The study of Fungi
Term
Life Cycle of Fungi
Definition
spore - hyphae - mycelium - spores
Term
Mycelium
Definition
the fungal body
Term
septate
Definition
fungi posessing a cell wall
Term
Yeasts
Definition
unicellular fungi
Term
Alfatoxin
Definition
Potent carcinogen produced by Aspergillus spp. of mold
Term
Pity Rosporumorbiculare
Definition
Causes Tinia versicolor AKAPityriasis vesicolor
Normal flora lipophilic yeast
Term
Piedraia hortae
Definition
trichomycosis or tinea nodosa
black growths (pietdra) on hair
Term
Trichosporon beigelii
Definition
White piedra
Term
Three genera of dermatophytes
Definition
Epidermatophytes
Trichophyton
Microsporium
Term
Cutaneous Mycoses
Definition
Dermatomycoses
Keratinase enzyme allows to adhere to skin
Causes ringworm
Term
Histoplasma capsulatum
Definition
Causes Hitoplasmosis AKA:
Darling's disease, Cave disease, spelunkers disease
Endemic in land that drains into ohio and Mississippi rivers
Usually flu like, can mimic TB
Term
Blastomyces dermatitidis
Definition
Chicago disease, Gilchrist's disease, North American blasomycosis
Lollipop conidium
can cause lesions of skin and bones
Term
Paracoccidioides brasilienses
Definition
Paracoccidioidomycosis, South American blastomycosis, LutzSplendore-Almeida disease
fungus may grow as yeast in tissues
Can cause ulcer like lesions
"Ships wheel" formation
Term
Coccidiodes immitis
Definition
Coccidioidomycosis AKA San Joaquin Valley Fever, AKA Destert Rheumatism and Posada disease
Barrel shaped infectious arthospores
Type B blood have greater risk of dissemination
Term
Cryptococcus neoformans
Definition
Causes:
Cryptococcosis AKA
Toulosos (yeast) AKA
European Blastomycosis AKA
BusseBuschke disease

worldwide thanks to dang pigeon droppings
May be mistaken for lung cancer
Primary cause of fungal meningitis
Term
Candida albicans
Definition
Opportunistic Mycoses
Result in: candidiasis, yeast infections, moniliasis, thrush
Term
Aspergillus species, especially A. flavus and A. fumigatus
Definition
cause asperfillosis
produces alphatoxin
Term
Zygomycetes
Definition
black bread mold
Infection requires underlying condition
Term
Pneumocystis carinii
Definition
atypical
once considdered a protazoa
causes a form of pneumonia
common cause of death in aids patients
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