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Metoclopramide
na
10
Nursing
Undergraduate 3
04/07/2014

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Term
Metoclopramide
Definition
Maxalon / Pramin ( Cat A)
Term
Action Metoclopramide
Definition
1. Prokinetic Agent
2.Stimulates the motility of the upper Gastrointestional Tract without affecing gastric,bilary or pancreatic secreations
3.Increases rate of gastric empting by enhancing perstalisis
4 . Increases resting tone of lower esophageal sphincter

5. Gas some dopamine antagonist activity

6. Increases Prolactin secreation
Term
Metoclopramide Uses
Definition
Nausea and vomitting
Enhances absorbtion of aspirin
Term
Metoclopramide dose
Definition
10-20 mg orally six hourly
Term
Interactions
Definition
1. Phenothiazine - extrapyramidal effects
2.Increase asbortion of aspirin, paracetmol, dizampam and controlled releases morphine
3.may decrease absorption of digoxin,cimetidine and penicillin
4.May potentiation action of cns depressants
5.Diabetic control may be affected
6.may increase seizure activity in epilepsy
7. Anti Chollenergic Drugs may reduce the effects
Term
Metoclopramide midwifery use
Definition
1. Cause of vomiting should be identified prior to treament
2.Compatiable with morphine and Pethidine
3. Slow IV over 1/2 minutes
4. Discard Ampoules
5. Warn women against driving
6. Seek medical advise if nausea vomitting ocntinues
Term
Prochlorperanzine
Definition
Stemetil (Cat c)
Term
Prochlorperazine Action and USE
Definition
1. Centerally acting phenothiazine that has antidopamine actions, anatagonise alpha adreno recptors. blocks nor adrenaline and has weak anti chollernergic , anti histamine and anti serotoninc actions

Used for vertigo
Term
Proclorperazine Midwifery Practice Points
Definition
1. Warn women from driving
2. If women has diabetes monitor blood sugars
3. skin may be sensitive to un
4.Phenytoin level should be monitored
Term
Proclorperazine Interactions
Definition
1. May Lowe convulsive threshold
2. thiazine diraretics may accentuate orthostationhypotenstion
3. May potentiation anti chollernergix effects of TCAS
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