Term
| What part of the mesoderm does the cardiovascular system arise from? |
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Definition
| Splanchnic (Subset of the lateral) mesoderm |
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Term
| What structures do the somites give rise to? |
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Definition
1. Axial skeleton
2. Axial musculature
3. Limb musculature
4. Dermis |
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Term
| What two types of cells border the extracellular matrix most predominantly? |
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Definition
1. Epithelia
2. Mesenchyme |
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Term
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Definition
Epithelial Mesenchyme Transformation
A process of cell transition characterized by loss of cell adhesion and increased cell mobility |
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Term
| Give an example of an inductive interaction involved in somite development |
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Definition
| SHH protein is released by the notochord, whose receptors stimulate the release of PAX1, transcription factors that are important in cell differentiation and somite formation |
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Term
| What role do Hox genes play in differentiation of the axial skeleton? |
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Definition
Different combinations of Hox genes in different segment of the axial skeleton lead to the development of vertebrae with fundamentally different shapes. Hox code is used for cells to read their location in the body.
Ex. lack of Hox10 gene generates growth of ribs on lumbar vertebrae |
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