Term
What is the neurtrasmitter effect of St. John's Wart and what can it cause if taken with AD meds? |
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Definition
Increase is seratonin
Seratonin syndroms |
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Term
What two drugs should you avoid taking St. John's Wart with? |
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Definition
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Term
Which drug?
Inhibits both AChE and BChE |
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Definition
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Term
Which drug?
May cause severe hepatotoxicity |
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Definition
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Term
Which drugs?
Must be administered 4 times daily
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Definition
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Term
Why does Cognex have compliance issues? |
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Definition
Must be taken 4 times daily |
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Term
Which drugs?
Reversible inhibitor of ChE |
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Definition
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Term
Which drugs?
More selective to AChE, but still commonly known for GI symptoms and bradycardia
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Definition
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Term
Which drug?
Has one daily dosing and can be taken with ot without food |
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Definition
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Term
Which drug?
Said to be irreversible (remains attached and forms a covalent bond with the enzyme) |
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Definition
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Term
Which drug?
Comes in a patch form |
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Definition
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Term
Which drug?
Short plasma half-life of 2 hours, but has inhibitory half-life of 10 hours |
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Definition
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Term
Which drug?
Not metabolized by the P-450 enzymes, so it does not interact with drugs metabolized by that system |
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Definition
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Term
Which drug?
Prefers AChE over BChE
(3) |
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Definition
1. Aricept
2. Excelon
3. Razadyne |
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Term
Which drug?
Stimulates presynaptic muscarinic receptors to release more Ach |
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Definition
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Term
Which drug?
May provide neuroprotection by up-regulating neurotrophic factors such as bcl-2 via nicotinic receptors |
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Definition
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Term
Which drug?
Half-life of 6 hours |
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Definition
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Term
What drug?
Metabolized by P-450 system and therefore interacts with drugs metabolized by this system |
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Definition
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Term
Which drug?
NDMA Antagonist |
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Definition
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Term
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Which drug?
Prevents glutamate from overstimulating the NDMA receptor |
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Definition
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Term
Which drug?
Results in the reduction in the number of depolarizations |
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Definition
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Term
Which drug?
Prevent neuronal degeneration |
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Definition
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Term
Abusers of this drug have symptoms similar to schizophrenic pt. |
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Definition
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Term
Too much stimulation of glutamate causes ____ and too little causes ____ |
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Definition
1. Neuronal death
2. Psychotic behavior |
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Term
Which drug?
Long half-life of 60-80 hours, but is not metabolized to a great degree |
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Definition
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Term
Which drug?
Usually co-prescribed with donepezil (Aricept) (Accounts for slower rates of deterioration) |
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Definition
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Term
Which drug?
Only drug approved by the U.S. Food and Drug Administration |
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Definition
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