Term
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Definition
| Neuroleptics (anticholinergic): seize the neuron, blocking the effects of dopamine w/many side effects (dirty drugs). Generally, they treat the positive symptoms of schizophrenia. Thorazine (low potency, may drop BP, 100 mg dose, sedative side fx). Haldol (high potency, EPS, every year on it the % chance of developing TD increases by 5%.) Prolixim (high potency, EPS). |
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Term
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Definition
In high doses, similar in side fx to typicals. 6-8mg/day. Treat positive and some negatives better than the typicals. Clozapine (clozaril, wbc's weekly (can cause agranulocytosis), a last resort med). Risperidone (risperdal, $$, wt gain.)
Zyprexa (olanzipine, dyslipidemia, type 2 diabetes). Seroquel (Quetiapine, sedative). Ziprasidone (Geodan, prolongs QT). Aripiprazole (ablify). |
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Term
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Definition
| Resting tremors. Usually @ a change in meds OR first dose. Dystonia (sustained muscle contractions can cause twisting and repetitive movements or abnormal postures)(can be treated with cogentin and benadryl injections). Acathesia (can't sit still). Pleurofacis (mask face). Tartive Dyskenisia and Chorea. the AIMS test screens for TD. |
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Term
| Positive symptoms of Schizophrenia |
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Definition
| Delusions. Halucinations. Bizarre behavior. Things you have you wish you didn't. |
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Term
| Negative Symptoms of Schizophrenia |
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Definition
| 4 A's. (Avolition (no will), Abulia (can't make a plan), Anhedonia (inability to enjoy pleasure), Ambivalent (unable to make a decision). Flat affect. Things that are missing that you wish you had. |
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Term
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Definition
| Part of forebrain. (right/left hemispheres, 4 lobes) |
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Term
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Definition
| Part of the forebrain that modulates mood behavior, appropriate muscle tone, and posture. |
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Term
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Definition
| Part of the forebrain. Connects the cerebrum with the lower brain structures. Contains the 4 Fs (fighting, fornicating, feeding, fleeing). |
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Term
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Definition
| Part of the Diencephalon. The Bagel or emotional brain. |
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Term
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Definition
| aka mesencephalon, responsible for visual, auditory, and balance reflexes. Substantia Nigra produces dopamine in this area. |
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Term
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Definition
Pons: regulates respiratory and muscle tone.
Medulla: regulates HR and BP
Cerebellum: muscle tone and coordination |
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Term
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Definition
| Composed of neurons. Cell bodies contain nuclei. Axons transmits messages to the next cell. Dendrites receive messages from cells. |
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Term
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Definition
Afferent (sensory)
Efferent (motor)
Interneurons in the CNS. |
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Term
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Definition
| Junction between neurons. Synaptic cleft is the space between neurons. Presynaptic neuron: area of axon where neurotransmitters are stored. Postsynaptic neuron: area of dendrite where receptor sites are located. |
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Term
| Acetylcholine (Cholinergic) |
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Definition
| Involved in sleep, arousal, movement, MEMORY. |
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Term
| Norepinephrine (Monoamine) |
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Definition
| mood, cognition, perception, location, cardiovascular functioning, sleep, arousal. |
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Term
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Definition
| movement, coordination, emotinos, voluntary judgement, release of prolactin, and emotional arousal, BUT inhibitory in basal ganglia. |
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Term
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Definition
| sleep, arousal, libido, appetite, mood, aggression, pain perception, coordination and judgement. |
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Term
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Definition
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Term
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Definition
| calming effect. an inhibitor neurotransmitter. |
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Term
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Definition
| Endorphins and enkephlins modulate pain and reduce peristalsis. 'natural opiates' |
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Term
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Definition
| direct control of the pituitary gland. the master gland. TSH, ACTH, melatonin. |
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