Term
|
Definition
Develop: male sex characteristics, bone and muscle tissue
inhbit protein catabolism
retention of various electrolytes |
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Term
|
Definition
Long term: 2-3 days to 2-4 weeks
PO high first pass
Transdermal forms: patch & gel |
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Term
|
Definition
fluid retention
anabolic steroids- peliosis of liver/other severe hepatic effect
irritability, hair loss, acne, dizzy, "roid rage"
shrinking of testes, impotence, sterility, and gynecomastia |
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Term
Androgen
Nursing implications |
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Definition
IM given deep
follow directions for PO, SL, buccal
testoderm applied to scrotal skin and androderm is never applied to scrotal skin. |
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Term
|
Definition
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Term
|
Definition
phosphodiesterase type 5 (PDE5)
enhances normal erectile response in presence of stimuli
aborption slowed by high fat meals |
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Term
|
Definition
Nitrates- dangerous hypotension
alpha blockers -sympotmatic postural hypotension
inhibitors of cytochrome P450-suppress metabolism of drug |
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Term
|
Definition
| hypotension, priapism, HA, dyspepsia, flushing, congestion, diarrhea, rash, dizzy, sleep apnea, |
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Term
|
Definition
pnts history of
MI, stroke, dysrhytmia w/i 6 months
resting hypotension
resting hypertension
heart failure
unstable angina |
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Term
|
Definition
PDE5 inhibitor II
relaxes arterial and trabecular smooth muscle in the penis |
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Term
|
Definition
nitrates- dangerous hypotension
alpha blockers- symptomatic postural hypotension
inhibitor of cytochrome P450- suppress metabolism of drug |
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Term
|
Definition
HA, flushing, cold, dyspepsia,
prolong QT interval,
hypotension
hearing and vision loss-rare |
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Term
|
Definition
PDE5 inhibitor II
relaxes the penile and arterial and trabecular smooth muscle
effects last up to 36 hours
daily dosing if activity anticipated twice weekly |
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Term
|
Definition
| HA, dyspepsia, back pain, myalgia, limb pain, flushing, congestion |
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Term
|
Definition
Nitrates
Alpha blockers except tamsulosin (flomax) |
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Term
| Papaverine with phentolamine |
|
Definition
smooth muscle relaxant with alpha adrenergic blocking agent
injected into corpus cavernosum
works w/i 20 minutes and can have coitus in 10 |
|
|
Term
Papaverine with phentolamine
Adverse effects |
|
Definition
priapism, painless fibrotic nodules in corpus cavernosum
orthostate hypotension with dizziness |
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Term
| Alprostadil (prostaglandin E1) |
|
Definition
injected directly into corpus cavernosum
increased arterial flow and decreased venous outflow in penis
shouldn't be used more than 3x week or 1x 24 hours |
|
|
Term
Alprostadil
adverse effects |
|
Definition
| burning, priapism, penile fibrosis |
|
|
Term
| 5 Alpha reductase inhibitors |
|
Definition
for mechanical obstruction
finasteride
dutasteride |
|
|
Term
| Alpha 1 adrenergic antagonists |
|
Definition
dynamic obstruction
hytrin
cardura
flomax
uroxatral |
|
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Term
|
Definition
Inhibits 5 alpha reductase
most effective in pnts with large prostates
-also for balding ex propecia
|
|
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Term
|
Definition
decrease ejaculate volume and libido
gynecomastia
decrease levels of PSA |
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Term
|
Definition
inhibits 5 alpha reductase
similar to proscar but
reduces circulating DHT is more complete
harmful is pregnant women touches esp with boy
long half life- 5 weeks |
|
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Term
|
Definition
pregnant women don't touch
educate on proper admin
monitor for theurapeutic responses- urinate
|
|
|
Term
Alpha 1 adrenergic Antagonists
Adverse Effects |
|
Definition
abnormal ejaculation
hyptension, faint, dizzy, somnolence, congestion |
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