Term
| Are nucleoli usually seen in the mature megakaryocyte nucleus? |
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Definition
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Term
| What multipotential stem cell does the megakaryocyte originate from? |
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Definition
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Term
| What hormone stimulates the production of CFU-Meg? |
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Definition
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Term
| What is the difference between stress platelets and regular platelets? |
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Definition
| Stress platelets are larger in size because of shorter maturation and release time; produced in response to thrombocytopenia. |
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Term
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Definition
| DNA replication without cytoplasmic divisions. Results in one multilobed nucleus. |
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Term
| A giant polyploid cell is produced by what process? |
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Definition
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Term
| The ploidy of the megakaryocyte correlates with what 2 things? |
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Definition
| Size of megakaryocyte and number of platelets produced. |
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Term
| At what ploidy does a megakaryocyte become morphologically recognizable as a megakaryocyte? |
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Definition
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Term
| Stages of megakaryocyte maturation- |
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Definition
| Megakaryoblast, Promegakaryocyte, Granular megakaryocyte, Mature megakaryocyte. |
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Term
| What is the N:C ratio of the megakaryoblast? |
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Definition
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Term
| How many nucleoli are present in the nucleus of the megakaryoblast? |
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Definition
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Term
| What shape is the megakaryoblast nucleus? |
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Definition
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Term
| What megakaryocyte precursor has blunt cytoplasmic projections or blebs at periphery? |
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Definition
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Term
| What stage is the earliest morphologically recognizable megakaryocyte? |
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Definition
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Term
| What is the shape of the promegakaryocyte nucleus? |
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Definition
|
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Term
| How many nucleoli are usually present in the promegakaryocyte? |
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Definition
|
|
Term
| What is the N:C ratio of the promegakaryocyte? |
|
Definition
|
|
Term
| What is the ploidy of the promegakaryocyte? |
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Definition
|
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Term
| What is the nucleus like in the granular megakaryocyte? |
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Definition
| condensed multilobulated nucleus- 8N- 32N |
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Term
| Can endomitosis occur in the granular megakaryocyte? |
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Definition
|
|
Term
| What is the N:C ratio in the mature megakaryocyte? |
|
Definition
|
|
Term
| What is the ploidy of the majority of the megakaryocytes in the bone marrow? |
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Definition
|
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Term
| Is it possible to determine ploidy of a megakaryocyte by looking at it? |
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Definition
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Term
| The average megakaryocyte releases how many platelets? |
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Definition
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Term
| After being released from the bone marrow, where do the baby platelets go? |
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Definition
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Term
| How long do platelets stay in the splenic platelet pool before being distributed throughout the body? |
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Definition
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Term
| How long do platelets survive? |
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Definition
|
|
Term
| What portion of the platelets is in the spleen at any given time? |
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Definition
|
|
Term
| What 3 kinds of granules are in the platelet? |
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Definition
| alpha, lysosomes, dense bodies. |
|
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Term
| What are the most numerous granules in the platelet? |
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Definition
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|
Term
| Contents of dense bodies? |
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Definition
| ADP, ATP, Ca2+, serotonin |
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