Term
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Definition
class: antigoagulant; antithrombotics
action: potentiates the inhibitory effect of antithrombin on factor Xa and thrombin
adverse effects: bleeding, anemia, dizziness, headache, insomnia, edema
interactions: durgs that affect platelet function and coagulation |
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Term
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Definition
class: anti-infective; carbapenems
action: bindsd to bacterial cell wall resulting in cell death. resists degrading actions of many enzymes.
adverse effects: seizures, pseudomembranous colitis, hypersensitivity reaction including anaphylaxis
interactions: probenecid, may decrease serum valproate levels |
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Term
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Definition
class: antiulcer agent; proton pump inhibitor
action: binds to an enzyme on gastric parietal cells in the presence of acidic gastric pH, preventing the final transport of hydrogen ions into the gastric lumen.
adverse: pseudomembranous colitis
interactions: atazanavir and nelfinavir, sanguinavir, ketoconazole, warfarin, clopidogrel, cilostazol, digoxin, methotrexate |
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Term
| gentamycin and sodium chloride 0.9% |
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Definition
class: cardioprotective agent
action: acts as an intracellular chelating agent
adverse effects: malignancy
interactions: antineoplastics, fluroruracil and cyclophosphamide |
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Term
| lactobacillus acidophilus and bulgarious (lacinex) |
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Definition
mixed culture of lactobaciullus acidophilus and L. bulgaricus
class: probiotic
action: promotes normal bacterial flora of the intestinal tract by producing lactic acid.
interactions: no known significant interactions.
adverse effects: bloating, flatulence |
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Term
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Definition
class: antianginals; antihypertensives; beta blocker
action: blocks stimulation of beta1-adrenergic receptors.
adverse effects: bradycardia, HF, pulmonary edema
interactions: general anesthesia, phenytoin, verapamil, digoxin, verapamil, diltiazem, clonidine, other antihypertensives, amphetamines, thyroid, theophylline, dopamine |
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Term
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Definition
class: antiemetics, antihistamines, sedative/hypnotics; phenothiazines
action: blocks the effects of histamine, inhibitory effect on chemoreceptor trigger zone in teh medulla, alters effects of dopamine
adverse reactions: neuroleptic malignant syndrome
interactions: other CNS depressants, antihistamines, antipsychotics, antidepressants, |
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Term
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Definition
class: allergy, cold, and cough remedies (antitussive) opioid analgesics
action: bind to opiate receptors in the CNS, altering perception of and response to painful stimuli while producing generalized CNS depression.
Adverse effects: confusion, dizziness, seduation, hypotension, constipation, nausea
interactions: MAO inhibitors CYP3A4 inhibitors and CYP3A4 ineuders |
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Term
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Definition
class: antiemetics; five ht3 antagonists
action: blocsk the effects of serotonin at 5HT3 receptor sites located in vagal nerve terminals and the chemoreceptor trigger zone in the CNS
adverse effects: torasde de pointes
interactions: apomorhpine, phenytoin, rifampin |
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Term
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Definition
class: antipyretic, nonopioid analgesic
action: inhibits the syntehsis of protaglandins; no significant anti-inflammatory properties or GI toxicity
adverse effects: hepatotoxicity, acute generalized exanthematous pustulosis, steven-johnson syndrome, toxic epidermal necrolysis
interactions: warfarin, isoniazid, rifampin, phenytoin, |
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Term
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Definition
| clinical syndrom that complicates severe infection characterized by teh cardinal signs of inflammation. Can lead to widespread tissue injury and multiple organ dysfunction syndrome. presence of viable bacteria in the blood. generally includes a high temperature, elevated heart rate, tachypnea, positive fluid balance, hyperglycemia, leukocytosis, hypertension and organ dysfunction variables. Treated with antimicrobial therapy.. |
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