Term
| What drug decreases HEPATIC GLUCOSE OUTPUT? |
|
Definition
|
|
Term
| What drug Increases INSULIN RESPONSIVENESS? |
|
Definition
|
|
Term
| What drugs increase endogenous insulin secretion? |
|
Definition
| Secretagogues- Sulfonylureas |
|
|
Term
| What drug increases starch/ disaccharide breakdown in gut? |
|
Definition
| Alpha Glucosidase Inhibitors; acarbose |
|
|
Term
| What IN secretion of insulin; DE appetite; DE glucagon, gastric emptying? |
|
Definition
- GLP-1 agonists (exenatide)
- Amylin agonists (pramlintide) |
|
|
Term
| What drug increases Glycosuria? |
|
Definition
| Renal Na-glucose transport inhibitors- ( |
|
|
Term
| What are the purposes of basal insulin? |
|
Definition
1) Suppresses glucose production between meals
2) Nearly constant levels
3) 50% of daily needs |
|
|
Term
| What are the purposes of bolus insulin (mealtime or prandial)? |
|
Definition
1) Limits hyperglycemia after meals
2) Immediate rise and sharp peak at 1 hr
3) 10-20% of daily requirement at each meal |
|
|
Term
| What are some of the benefits of Short-Acting Analogs: Lispro and Aspart? |
|
Definition
1) Convenient administration
–Immediately prior to meals
2) Faster onset of action
3) Limit postprandial hyperglycemic peaks
4) Shorter duration of activity
–Reduce late postprandial hypoglycemia
–Frequent late postprandial hyperglycemia
5) Uncover need for basal insulin replacement |
|
|
