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        | cerebrum (largest part of the brain) |  | 
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        | cerebellum (little brain) |  | 
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        | spinal cord or bone marrow |  | 
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        | exaggerated fear or sensitivity |  | 
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        | three-dimensional or solid |  | 
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        | ventricle (belly or pouch) |  | 
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        | condition of abnormal impulse toward |  | 
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        | central nervous system (CNS) |  | Definition 
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        | portion of the central nervous system contained within the cranium |  | 
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        | largest portion of the brain; divided into right and left halves, known as cerebral hemispheres, which are connected by a bridge of nerve fibers called the corpus callosum; lobes of the cerebrum are named after the skull bones they underlie |  | 
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        | anterior section of each cerebral hemisphere; responsible for voluntary muscle movement and personality |  | 
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        | portion posterior to the frontal lobe; responsible for sensations such as pain, temperature, and touch |  | 
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        | portion that lies below the frontal lobe; responsible for hearing, taste, and smell |  | 
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        | portion posterior to the parietal and temporal lobes;responsible for vision |  | 
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        | outer layer of the cerebrum consisting of gray matter; responsible for higher mental functions (cortex = bark) |  | 
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        | each of two gray matter nuclei deep within the brain; responsible for relaying sensory information to the cortex |  | 
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        | convolutions (mounds) of the cerebral hemispheres |  | 
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        | shallow grooves that separate gyri |  | 
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        | deep grooves in the brain |  | 
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        | portion of the brain located below the occipital lobes of the cerebrum; responsible for control and coordination of skeletal muscles |  | 
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        | region of the brain that serves as a relay between the cerebrum, cerebellum, and spinal cord; responsible for breathing, heart rate, and body temperature; the three levels are the mesencephalon (midbrain), pons, and medulla oblongata |  | 
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        | series of interconnected cavities within the cerebral hemispheres and brainstem filled with cerebrospinal fluid |  | 
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        | cerebrospinal fluid (CSF) |  | Definition 
 
        | plasma-like clear fluid circulating in and around the brain and spinal cord |  | 
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        | column of nervous tissue from the brainstem through the vertebrae; responsible for nerve conduction to and from the brain and the body |  | 
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        | three membranes that cover the brain and spinal cord, consisting of the dura mater, pia mater, and arachnoid mater |  | 
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        | peripheral nervous system (PNS) |  | Definition 
 
        | nerves that branch from the central nervous system including nerves of the brain (cranial nerves) and spinal cord (spinal nerves) |  | 
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        | 12 pairs of nerves arising from the brain |  | 
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        | 31 pairs of nerves arising from the spinal cord |  | 
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        | nerves that conduct impulses from body parts and carry sensory information to the brain; also called afferent nerves (ad = toward; ferre = carry) |  | 
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        | nerves that conduct motor impulses from the brain to muscles and glands; also called efferent nerves (e = out; ferre = carry) |  | 
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        | autonomic nervous system (ANS) |  | Definition 
 
        | nerves that carry involuntary impulses to smooth muscle, cardiac muscle, and various glands |  | 
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        | control center for the autonomic nervous system located below the thalamus (diencephalon) |  | 
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        | sympathetic nervous system |  | Definition 
 
        | division of the autonomic nervous system that is concerned primarily with preparing the body in stressful or emergency situations |  | 
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        | parasympathetic nervous system |  | Definition 
 
        | division of the autonomic nervous system that is most active in ordinary conditions; it counterbalances the effects of the sympathetic system by restoring the body to a restful state after a stressful experience |  | 
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        | impairment because of localized brain injury that affects the understanding, retrieving, and formulating of meaningful and sequential elements of language, as demonstrated by an inability to use or comprehend words; occurs as a result of a stroke, head trauma, or disease |  | 
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        | a general term referring to levels of decreased consciousness with varying responsiveness; a common method of assessment is the Glasgow Coma Scale |  | 
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        | a state of mental confusion caused by disturbances in cerebral function; the many causes include fever, shock, and drug overdose (deliro = to draw the furrow awry when plowing, to go off the rails) |  | 
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        | an impairment of intellectual function characterized by memory loss, disorientation, and confusion (dementio = to be mad) |  | 
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        | loss or impairment of muscle function |  | 
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        | loss or impairment of sensation |  | 
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        | pain along the course of a nerve |  | 
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        | temporary or permanent loss of motor control |  | 
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        | defective (flabby) or absent muscle control caused by a nerve lesion |  | 
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        | stiff and awkward muscle control caused by a central nervous system disorder |  | 
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        | partial paralysis of the right or left half of the body |  | 
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        | pain that follows the pathway of the sciatic nerve, caused by compression or trauma of the nerve or its roots |  | 
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        | sudden, transient disturbances in brain function resulting from an abnormal firing of nerve impulses; may or may not be associated with convulsion |  | 
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        | to pull together; type of seizure that causes a series of sudden, involuntary contractions of muscles |  | 
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        | evoking a response by touching |  | 
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        | increased sensitivity to stimulation such as touch or pain |  | 
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        | abnormal sensation of numbness and tingling without objective cause |  | 
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        | any of many types of loss of neurologic function involving interpretation of sensory information |  | 
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        | inability to judge the form of an object by touch (e.g., a coin from a key) |  | 
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        | inability to locate a sensation properly, such as an inability to locate a point touched on the body |  | 
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        | disease of structural changes in the brain resulting in an irreversible deterioration that progresses from forgetfulness and disorientation to loss of all intellectual functions, total disability, and death |  | 
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        | amyotrophic lateral sclerosis (ALS) |  | Definition 
 
        | condition of progressive deterioration of motor nerve cells resulting in total loss of voluntary muscle control; symptoms advance from muscle weakness in the arms and legs, to the muscles of speech, swallowing, and breathing, to total paralysis and death; also known as Lou Gehrig disease |  | 
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        | condition of motor dysfunction caused by damage to the cerebrum during development or injury at birth; characterized by partial paralysis and lack of muscle coordination (palsy =) |  | 
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        | isorder resulting from a change within one or more blood vessels of the brain |  | 
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        | cerebral arteriosclerosis |  | Definition 
 
        | hardening of the arteries of the brain |  | 
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        | condition of lipid (fat) buildup within the blood vessels of the brain (ather/o = fatty [lipid] paste) |  | 
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        | dilation of a blood vessel in the brain (aneurysm = dilation or widening) |  | 
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        | presence of a stationary clot in a blood vessel of the brain |  | 
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        | obstruction of a blood vessel in the brain by an embolus transported through the circulation |  | 
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        | cerebrovascular accident (CVA) (Fig. 8-6)stroke |  | Definition 
 
        | damage to the brain caused by cerebrovascular disease, such as occlusion of a blood vessel by a thrombus or embolus (ischemic stroke) or intracranial hemorrhage after rupture of an aneurysm (hemorrhagic stroke) |  | 
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        | Term 
 
        | transient ischemic attack (TIA) |  | Definition 
 
        | brief episode of loss of blood flow to the brain, usually caused by a partial occlusion that results in temporary neurologic deficit (impairment); often precedes a CVA |  | 
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 | Definition 
 
        | inflammation of the brain |  | 
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 | Definition 
 
        | disorder affecting the central nervous system; characterized by recurrent seizures |  | 
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 | Definition 
 
        | stiffening-jerking; a major motor seizure involving all muscle groups; previously termed grand mal (big bad) seizure |  | 
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        | seizure involving a brief loss of consciousness without motor involvement; previously termed petit mal (little bad) seizure |  | 
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        | seizure involving only limited areas of the brain with localized symptoms |  | 
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        | tumor of glial cells graded according to degree of malignancy |  | 
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        | disk protrusion of a degenerated or fragmented intervertebral disk so that the nucleus pulposus protrudes, causing compression on the nerve root |  | 
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        | viral disease affecting the peripheral nerves, characterized by painful blisters that spread over the skin following the affected nerves, usually unilateral; also known as shingles |  | 
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        | Huntington chorea, Huntington disease (HD) |  | Definition 
 
        | hereditary disease of the central nervous system characterized by bizarre, involuntary body movements and progressive dementia (choros = dance) |  | 
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        | abnormal accumulation of cerebrospinal fluid in the ventricles of the brain as a result of developmental anomalies, infection, injury, or tumor |  | 
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        | benign tumor of the coverings of the brain (the meninges) |  | 
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        | inflammation of the meninges |  | 
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 | Definition 
 
        | paroxysmal (sudden, periodic) attacks of mostly unilateral headache, often accompanied by disordered vision, nausea, or vomiting, lasting hours or days and caused by dilation of arteries |  | 
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 | Definition 
 
        | disease of the central nervous system characterized by the demyelination (deterioration of the myelin sheath) of nerve fibers, with episodes of neurologic dysfunction (exacerbation) followed by recovery (remission) |  | 
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        | autoimmune disorder that affects the neuromuscular junction, causing a progressive decrease in muscle strength; activity resumes and strength returns after a period of rest |  | 
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        | nflammation of the spinal cord |  | 
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        | sleep disorder characterized by a sudden, uncontrollable need to sleep, attacks of paralysis (cataplexy), and dreams intruding while awake (hypnagogic hallucinations) |  | 
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 | Definition 
 
        | congenital deformities of the brain and spinal cord caused by incomplete development of the neural tube, the embryonic structure that forms the nervous system |  | 
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 | Definition 
 
        | defect in closure of the cephalic portion of the neural tube that results in incomplete development of the brain and bones of the skull; the most drastic neural tube defect usually results in a stillbirth |  | 
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 | Definition 
 
        | defect in development of the spinal column characterized by the absence of vertebral arches, often resulting in pouching of the meninges (meningocele) or of the meninges and spinal cord (meningomyelocele); considered to be the most common neural tube defect (spina = spine; bifida = split into two parts) |  | 
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        | condition of slowly progressive degeneration in an area of the brainstem (substantia nigra) resulting in a decrease of dopamine (a chemical neurotransmitter necessary for proper movement); characterized by tremor, rigidity of muscles, and slow movements (bradykinesia); usually occurs later in life |  | 
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        | paralysis on one side of the body |  | 
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        | paralysis from the waist down |  | 
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        | paralysis of all four limbs |  | 
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        | inflammation of the gray matter of the spinal cord caused by a virus, often resulting in spinal and muscle deformity and paralysis (polio = gray) |  | 
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        | nflammation involving two or more nerves, often caused by a nutritional deficiency, such as lack of thiamine |  | 
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        | periods of breathing cessation (10 seconds or more) that occur during sleep, often causing snoring |  | 
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        | electrodiagnostic procedures |  | Definition 
 
        | diagnostic procedures used to evaluate the function of the nervous system by recording the electrical signals produced in the brain, spinal cord, and peripheral nerves |  | 
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        | electroencephalogram (EEG) |  | Definition 
 
        | record of the minute electrical impulses of the brain; used to identify neurologic conditions that affect brain function and level of consciousness |  | 
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        | record of minute electrical potentials (waves) that are extracted from ongoing EEG activity to diagnose auditory, visual, and sensory pathway disorders; also used to monitor the neurologic function of patients during surgery |  | 
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 | Definition 
 
        | recording of various aspects of sleep (e.g., eye and muscle |  | 
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        | movements, respiration, and EEG patterns) to diagnose sleep disorders |  | 
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        | introduction of a specialized needle into the spine in the lumbar region for diagnostic or therapeutic purposes, such as to obtain CSF for testing; also called spinal tap |  | 
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        | Term 
 
        | magnetic resonance imaging (MRI) |  | Definition 
 
        | nonionizing imaging technique using magnetic fields and radiofrequency waves to visualize anatomic structures (especially soft tissue), such as the tissues of the brain and spinal cord |  | 
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        | magnetic resonance angiography (MRA) |  | Definition 
 
        | magnetic resonance imaging of blood vessels to detect pathologic conditions, such as thrombosis and atherosclerosis |  | 
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 | Definition 
 
        | magnetic resonance image of the head to visualize the vessels of the circle of Willis (common site of cerebral aneurysm, stenosis, or occlusion) |  | 
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        | magnetic resonance image of the neck to visualize the carotid artery |  | 
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 | Definition 
 
        | radionuclide organ imaging |  | 
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        | single-photon emission computed tomography (SPECT) brain scan |  | Definition 
 
        | scan combining nuclear medicine and computed tomography to produce images of the brain after the administration of radioactive isotopes |  | 
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        | positron-emission tomography (PET) |  | Definition 
 
        | technique combining nuclear medicine and computed tomography to produce images of brain anatomy and corresponding physiology; used to study stroke, Alzheimer disease, epilepsy, metabolic brain disorders, chemistry of nerve transmissions in the brain, and so on; provides greater accuracy than SPECT, but is used less often because of cost and the limited availability of the radioisotopes |  | 
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        | x-ray of blood vessels in the brain after intracarotid injection of contrast medium |  | 
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        | computed tomography (CT) of the head |  | Definition 
 
        | computed tomographic (x-ray) images of the head used to visualize abnormalities, such as brain tumors and malformations |  | 
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 | Definition 
 
        | x-ray of the spinal cord obtained after intraspinal injection of contrast medium |  | 
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        | test performed to observe the body's response to a stimulus |  | 
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        | Term 
 
        | deep tendon reflexes (DTR) |  | Definition 
 
        | involuntary muscle contraction after percussion at a tendon (e.g., patella or Achilles) indicating function; positive findings are either no reflex response or an exaggerated response to stimulus; numbers are often used to record responses, F = no response (absent reflex), 1+ = diminished response, 2+ = normal response, 3+ = more brisk than average response, 4+ = hyperactive response |  | 
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 | Definition 
 
        | pathologic response to stimulation of the plantar surface of the foot; a positive sign is indicated when the toes dorsiflex |  | 
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 | Definition 
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        | Term 
 
        | transcranial Doppler sonogram |  | Definition 
 
        | image made by sending ultrasound beams through the skull to assess blood flow in intracranial vessels; used in the diagnosis and management of stroke and head trauma |  | 
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 | Definition 
 
        | incision and coring of the lining of the carotid artery to clear a blockage caused by the buildup of atherosclerotic plaque or a clot; an open procedure used to treat patients who are at risk for stroke |  | 
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 | Definition 
 
        | excision of part of the skull to approach the brain |  | 
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 | Definition 
 
        | incision into the skull to approach the brain |  | 
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 | Definition 
 
        | removal of a herniated disk; often done percutaneously (per = through; cutaneous = skin) |  | 
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 | Definition 
 
        | minimally invasive techniques for diagnosis and treatment of |  | 
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 | Definition 
 
        | disorders within blood vessels of the neck, brain, and spinal cord using specialized catheters inserted percutaneously |  | 
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        | Term 
 
        | interventional neuroradiology |  | Definition 
 
        | (through the skin) into the femoral artery (in the groin) and guided by angiographic imaging to the treatment site; performed in a specialized angiographic laboratory by interventional neuroradiologists; common procedures are: percutaneous transluminal angioplasty (PTA) with stent (e.g., carotid PTA) • embolization (plugging) of intracranial aneurysms and vascular malformations |  | 
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 | Definition 
 
        | excision of one or more laminae of the vertebrae to approach the spinal cord |  | 
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 | Definition 
 
        | flattened posterior portion of the vertebral arch |  | 
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 | Definition 
 
        | use of a microscope to dissect minute structures during surgery |  | 
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 | Definition 
 
        | surgical repair of a nerve |  | 
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 | Definition 
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        | Term 
 | Definition 
 
        | treatment of malignancies, infections, and other diseases with chemical agents to destroy selected cells or impair their ability to reproduce |  | 
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 | Definition 
 
        | treatment of neoplastic disease using ionizing radiation to impede the proliferation of malignant cells |  | 
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        | Term 
 
        | stereotactic or stereotaxic |  | Definition 
 
        | radiation treatment to inactivate malignant lesions using |  | 
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        | Term 
 | Definition 
 
        | multiple, precise external radiation beams focused on a target with the aid of a stereotactic frame and imaging such as CT, MRI, or angiography; used to treat inoperable brain tumors and other lesions |  | 
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        | Term 
 
        | stereotactic or stereotaxic |  | Definition 
 
        | mechanical device used to localize a point in space, |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
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 | Definition 
 
        | agent that prevents or lessens convulsion |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | emotional feeling or mood |  | 
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 | Definition 
 
        | significantly dulled emotional tone or outward reaction |  | 
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        | Term 
 | Definition 
 
        | a lack of interest or display of emotion |  | 
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        | Term 
 | Definition 
 
        | a state of unresponsiveness to one's outside environment, usually including muscle rigidity, staring, and inability to communicate |  | 
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        | Term 
 | Definition 
 
        | a persistent belief that has no basis in reality |  | 
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        | Term 
 | Definition 
 
        | a person's false belief that he or she possesses great wealth, intelligence, or power |  | 
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 | Definition 
 
        | a person's false belief that someone is plotting against him or her with the intent to harm |  | 
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 | Definition 
 
        | a restless, dissatisfied mood |  | 
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        | Term 
 | Definition 
 
        | an exaggerated, unfounded feeling of well-being |  | 
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        | Term 
 | Definition 
 
        | a false perception of the senses for which there is no reality; most commonly hearing or seeing things (alucinor = to wander in mind) |  | 
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        | Term 
 | Definition 
 
        | the formation of thoughts or ideas, such as suicidal ideation (thoughts of suicide) |  | 
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        | Term 
 | Definition 
 
        | state of abnormal elation and increased activity |  | 
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        | Term 
 | Definition 
 
        | a psychologic condition in which anxiety is prominent |  | 
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        | Term 
 | Definition 
 
        | a mental condition characterized by distortion of reality resulting in the inability to communicate or function within one's environment |  | 
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        | Term 
 | Definition 
 
        | thought that lacks clear processing or logical direction |  | 
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        | Term 
 
        | major depression,major depressive illness, clinical depression,major affective disorder,unipolar disorder |  | Definition 
 
        | a disorder causing periodic disturbances in mood that affect concentration, sleep, activity, appetite, and social behavior; characterized by feelings of worthlessness, fatigue, and loss of interest |  | 
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        | Term 
 | Definition 
 
        | a milder affective disorder characterized by chronic depression |  | 
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        | Term 
 
        | manic depression,bipolar disorder (BD) |  | Definition 
 
        | an affective disorder characterized by mood swings of mania and depression (extreme up and down states) |  | 
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        | Term 
 
        | seasonal affective disorder (SAD) |  | Definition 
 
        | an affective disorder marked by episodes of depression that most often occur during the fall and winter and that remitin the spring |  | 
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        | Term 
 
        | generalized anxiety disorder (GAD) |  | Definition 
 
        | the most common anxiety disorder; characterized by chronic, excessive, uncontrollable worry about everyday problems; affects the ability to relax or concentrate, but does not usually interfere with social interactions or employment; physical symptoms include muscle tension, trembling, twitching, fatigue, headaches, nausea, and insomnia |  | 
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        | Term 
 | Definition 
 
        | a disorder of sudden, recurrent attacks of intense feelings, including physical symptoms that mimic a heart attack (rapid heart rate, chest pain, shortness of breath, chills, sweating, and dizziness) with a general sense of loss of control or feeling that death is imminent; often progresses to agoraphobia |  | 
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        | Term 
 | Definition 
 
        | exaggerated fear of a specific object or circumstance that causes anxiety and panic; named for the object or circumstance, such as agoraphobia (fear of the marketplace), claustrophobia (fear of confinement), and acrophobia (fear of high places) |  | 
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        | Term 
 
        | posttraumatic stress disorder (PTSD) |  | Definition 
 
        | a condition resulting from an extremely traumatic experience, injury, or illness that leaves the sufferer with persistent thoughts and memories of the ordeal; may occur after a war, violent personal assault, physical or sexual abuse, serious accident, or natural disaster; symptoms include feelings of fear, detachment, exaggerated startle response, restlessness, nightmares, and avoidance of anything or anyone who triggers the painful recollections |  | 
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        | Term 
 
        | obsessive-compulsive disorder (OCD) |  | Definition 
 
        | an anxiety disorder featuring unwanted, senseless obsessions accompanied by repeated compulsions; can interfere with all aspects of a person's daily life; for example, the thought that a door is not locked causing repetitive checking to make sure it is locked, or thoughts that one's body has been contaminated causing repetitive washing |  | 
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 | Definition 
 
        | a preoccupation with thoughts of disease and concern that one is suffering from a serious condition that persists despite medical reassurance to the contrary |  | 
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        | Term 
 | Definition 
 
        | a developmental disability, commonly appearing during the first three years of life, resulting from a neurologic disorder affecting brain function, as evidenced by difficulties with verbal and nonverbal communication and an inability to relate to anything beyond oneself (auto = self) in social interactions; persons with autism often exhibit body movements such as rocking and repetitive hand movements; persons commonly become preoccupied with observing.  parts of small objects or moving parts or with performing meaningless rituals |  | 
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 | Definition 
 
        | a developmental disability characterized by difficulty understanding written or spoken words, sentences, or paragraphs that affects reading, spelling, and self-expression |  | 
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        | attention-deficit/hyperactivity disorder (ADHD) |  | Definition 
 
        | a dysfunction characterized by consistent hyperactivity, distractibility, and lack of control over impulses, which interferes with ability to function normally at school, home, or work |  | 
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 | Definition 
 
        | a condition of subaverage intelligence characterized by an IQ of 70 or less, resulting in the inability to adapt to normal social activities |  | 
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        | Term 
 | Definition 
 
        | a severe disturbance in eating behavior caused by abnormal perceptions about one's body weight, as evidenced by an overwhelming fear of becoming fat that results in a refusal to eat and body weight well below normal |  | 
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        | Term 
 | Definition 
 
        | an eating disorder characterized by binge eating followed by efforts to limit digestion though induced vomiting, use of laxatives, or excessive exercise |  | 
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        | Term 
 
        | substance abuse disorders |  | Definition 
 
        | mental disorders resulting from abuse of substances such as drugs, alcohol, or other toxins, causing personal and social dysfunction; identified by the abused substance, such as alcohol abuse, amphetamine abuse, opioid (narcotic) abuse, and polysubstance abuse |  | 
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        | Term 
 | Definition 
 
        | a disease of brain chemistry causing a distorted cognitive and emotional perception of one's environment; symptoms include distortions of normal function (such as disorganized thought, delusions, hallucinations, and catatonic behavior), flat affect, apathy, and withdrawal from reality |  | 
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        | Term 
 
        | electroconvulsive therapy |  | Definition 
 
        | (ECT) electrical shock applied to the brain to induce convulsions; used to treat patients with severe depression |  | 
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        | Term 
 | Definition 
 
        | use of specialized illuminating light boxes and visors to treat seasonal affective disorder |  | 
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        | Term 
 | Definition 
 
        | treatment of psychiatric disorders using verbal and nonverbal interaction with patients, individually or in a group, employing specific actions and techniques |  | 
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        | Term 
 | Definition 
 
        | treatment to decrease or stop unwanted behavior |  | 
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        | Term 
 | Definition 
 
        | treatment to change unwanted patterns of thinking |  | 
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        | Term 
 | Definition 
 
        | medications used to treat mental illnesses (trop/o = a turning) |  | 
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        | Term 
 
        | antianxiety,anxiolytic agents |  | Definition 
 
        | agents drugs used to reduce anxiety |  | 
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        | Term 
 | Definition 
 
        | agent that counteracts depression |  | 
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        | Term 
 | Definition 
 
        | gents drugs used to treat psychosis, especially schizophrenia |  | 
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        | Term 
 | Definition 
 
        | agent that has a calming effect and quiets nervousness |  | 
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        | Term 
 | Definition 
 
        | amyotrophic lateral sclerosis |  | 
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        | Term 
 | Definition 
 
        | attention-deficit/hyperactivity disorder |  | 
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 | Definition 
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 | Definition 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
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        | electroconvulsive therapy |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | generalized anxiety disorder |  | 
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        | Term 
 | Definition 
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 | Definition 
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        | magnetic resonance angiography |  | 
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        | Term 
 | Definition 
 
        | magnetic resonance imaging |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | nerve conduction velocity |  | 
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        | Term 
 | Definition 
 
        | obsessive-compulsive disorder |  | 
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        | Term 
 | Definition 
 
        | positron-emission tomography |  | 
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        | Term 
 | Definition 
 
        | peripheral nervous system |  | 
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 | Definition 
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        | Term 
 | Definition 
 
        | posttraumatic stress disorder |  | 
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        | Term 
 | Definition 
 
        | seasonal affective disorder |  | 
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        | Term 
 | Definition 
 
        | single-photon emission computed tomography |  | 
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        | Term 
 | Definition 
 
        | transient ischemic attack |  | 
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