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Medical Microbiology 9-22
9-22 (Helminths I)
11
Microbiology
Professional
09/22/2010

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Cards

Term
General characteristics of Trematodes
Definition
>flat body with syncytial tegument
>no cilia
>oral sucker, sometimes ventral sucker
>complex life cycles with 1-2 intermediate hosts
>1st host is always a mollusk
>hermaphrodites
Term
During what stages of a trematodes life cycle do humans become infected?
Definition
Cercaria
Metacercaria
Adult
Term
Clonorchis sinensis
Opisthorchis sinensis
Definition
"Chinese liver fluke"
>Sx=diarrhea, edema, pain, hepatitis, hepatomegaly, jaundice, ascites, death
>Dx=detect eggs in feces
>Hx=eat raw fish
Term
Fascioloa hepatica
Definition
"sheep liver fluke"
sheep, cattle, men.
>Sx=damage to liver as juveniles, migrates ectopically
>Dx=eggs in feces
>Hx=eating plants infected with metacercaria
Term
Fasciolopsis buski
Definition
"Intestinal fluke"
Pigs and men
>Sx=hemorrhage and abscess of small intestine
>Dx=eggs in feces
>Hx=eating vegetation or pork infected with metacercaria
Term
Paragonimus westermani
Definition
"lung fluke"
carnivores, pigs, rodents, man
>Sx=Hemoptysis, chronic cough, secondary bacteria infection; due to adults living in fibrosis in lungs
>Dx=detection of eggs in brown streaks of sputum, radiological
>Hx=eating raw crabs or crustaceans which have the metacercaria
Term
Name the non Schistosome flukes
Definition
> Clorochis sinensis
>Fascioloa hepatica
>Fasciolopsis buski
>Paragonimus westermani
Term
Schistosomiasis mansoni and japonicum
(egg morphology, disease, locations)
Definition
"snail fever" bilharzia
S.mansoni
>adult has 8 testes
>location: GI with spines to get through inferior mesentereic veins and deposit eggs into poop
S.japonicum
>location: GI with spines to get through inferior mesentereic veins and deposit eggs into poop
>spines small so has 10x higher egg production

Disease=Katayama fever in acute. Granulomas around eggs in liver which block hepatic flow, ascites, GI hemorrhage
Term
Schistosoma haematobium
Definition
adult has 4-5 testes
>location: venous plexuses around bladder
>eggs: conspicuous terminal spine
>intermediate host: Bulinus truncatus
>pathology: eggs cause calcification of bladder wall=hydronephrosis, SQUAMOUS cell carcinoma
Term
Characteristics of Schistosomes
Definition
blood parasites
dioecious=male and females separated
direct penetration of host
no metacercarial stage
no operculate (shell) eggs
furcocercous cercaria (forked cercaria)
Term
Schistosome clinical manifestations
Definition
1)dermatitis at site of cercaria penetration
2)Katayama fever (HA, wt loss, cough)
3)chronic fibrosis from eggs spreading systemically.
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