Term
| myasthenia gravis results in... |
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Definition
| destruction of ACh receptors at NM junction |
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Term
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Definition
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Term
| small acyl group is good for |
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Definition
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Term
| increasing acyl group size increases |
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Definition
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Term
| alkyl substitutions on Beta carbon decreases _______ action |
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Definition
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Term
| increasing ______ on amine group will change compound from agonist to antagonist |
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Definition
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Term
| _____ is identical to acetylcholine except the CH3 is replaced with an NH2 |
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Definition
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Term
| can reduce intraocular pressure when pilocarpine or neostigmine fail |
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Definition
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Term
| pilocarpine treats _____ by _____ |
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Definition
| glaucoma; better draining of ocular fluid through canal of schlemn |
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Term
| indirect cholinergic agents work by? |
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Definition
| blocking action of acetylcholinesterase |
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Term
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Definition
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Term
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Definition
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Term
| carry impulses from periphery to CNS |
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Definition
| sensory / afferent nerves |
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Term
| impulses from CNS to periphery |
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Definition
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Term
| parasympathetic nervous system - where it comes out |
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Definition
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Term
| sympathetic nervous system - where it comes out |
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Definition
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Term
| parasympathetic has _____ preganglionic axons |
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Definition
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Term
| sympathetic has ____ preganglinoic axons |
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Definition
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Term
| first neurotransmitter released from spinal cord in autonomic system |
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Definition
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Term
| connection between 2 neurons |
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Definition
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Term
| connection between neuron and innervated tissue |
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Definition
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Term
| excitatory CNT release results in ______ of postsynaptic cell |
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Definition
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Term
| inhibitory CNT release results in ______ of post synaptic membrane |
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Definition
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Term
| action of CNT terminated by THREE major mechanisms |
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Definition
| uptake, metabolism, diffusion |
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Term
| cholinergic nerves result in ____ of GI tract |
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Definition
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Term
| cholinergic nerves regulate _______ and ______ of the heartbeat |
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Definition
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Term
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Definition
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Term
| butyrylcholinesterase is primarily found in ____ |
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Definition
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Term
| first receptor ACh interacts with is _______ |
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Definition
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Term
| trimethylamine group is a better inhibitor in the ____ position than the ____ position |
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Definition
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Term
| alzheimers results in reduced _______ receptor levels |
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Definition
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Term
| enzyme responsible for biosynthesis of ACh |
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Definition
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Term
| aricept/donepezil is metabolized to an active phenol by _______ |
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Definition
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Term
| phosphate esters are capable of |
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Definition
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Term
| organophosphates cause ACh to ______ at nerve endings |
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Definition
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Term
| _____ is used to reverse the effects of nerve agents or insecticides |
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Definition
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Term
| postganglionic neurotransmitter in sympathetic system |
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Definition
| epinephrine or norepinephrine |
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Term
| postganglionic neurotransmitter in parasympathetic neuron |
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Definition
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Term
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Definition
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Term
| anticholinergics ____ secretion of saliva and gastric juices |
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Definition
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Term
| tiotropium/Spiriva blocks __ receptors in the airways |
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Definition
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