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MED109 Ignacio Nunez
Integumentary System Terminology
85
Medical
Not Applicable
02/26/2026

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Cards

Term
Epidermis
Definition
The outermost layer, made up of stratified squamous epithelial cells. It provides a protective barrier and contains specialized cells like melanocytes, which produce melanin, a pigment that protects against UV radiation.
Term
Dermis
Definition
The middle layer, containing connective tissue, blood vessels, nerves, hair follicles, and glands. It provides structural support and houses sensory receptors and sweat glands.
Term
Subcutaneous Layer (Hypodermis)
Definition
The deepest layer, composed of fat and connective tissue. It insulates the body and serves as an energy reserve.
Term
Hair
Definition

 

Comprised of keratinized cells, it provides insulation, protection, and sensory input. Hair follicles are rooted in the dermis and are associated with sebaceous glands that secrete sebum, an oil that moisturizes the skin.

Term
Nails
Definition
Formed from hard keratin, they protect the tips of fingers and toes and assist in fine motor functions
Term
Sweat Glands (Sudoriferous Glands)
Definition
Help cool the body through perspiration and play a role in excreting waste.
Term
Sebaceous Glands
Definition
 Secrete sebum to lubricate and waterproof the skin and hair
Term
a-, an-: Absence of, without, not Example: Anhidrosis
Definition
The absence of sweating, which can result from damage to sweat glands, certain medications, or neurological disorders, potentially leading to overheating or heatstroke.
Term
bi-: Two or both Example: Bilateral
Definition
Pertaining to both sides, such as a bilateral rash that appears symmetrically on both sides of the body, often associated with systemic conditions like lupus.
Term
dia-
Definition
Through, complete Example: Diaphoresis – Excessive sweating, which may be a symptom of fever, physical exertion, or underlying conditions like hyperthyroidism or a heart attack
Term
dys-
Definition
Difficult, painful, abnormal, labored Example: Dysplasia – Abnormal development or growth of tissue, often referring to precancerous changes in the skin or mucous membranes, such as cervical dysplasia.
Term
epi-
Definition
Upon, on, over Example: Epidermis – The outermost layer of the skin, which acts as a protective barrier against environmental damage, pathogens, and water loss.
Term
hyper-
Definition
Above, excessive Example: Hyperkeratosis – Thickening of the skin’s outer layer due to excessive keratin production, often seen in conditions like psoriasis, calluses, or warts
Term
hypo-
Definition
Deficient, below, under, incomplete Example: Hypodermic – Pertaining to beneath the skin, often used to describe injections administered into the subcutaneous tissue for rapid absorption of medications.
Term
intra-
Definition
Within, in Example: Intradermal – Within the layers of the skin, as in intradermal injections used for allergy testing or tuberculosis screening.
Term
meta-
Definition
Change, beyond, after Example: Metaplasia – Transformation of tissue from one type to another, such as the conversion of normal skin cells to a tougher type after chronic irritation or injury.
Term
neo-
Definition
New Example: Neoplasm – A new growth of abnormal tissue, which can be benign (like a mole) or malignant (like melanoma), requiring medical evaluation for treatment.
Term
para-
Definition
Beside, around, beyond, abnormal Example: Paronychia – Inflammation around a nail, typically caused by bacterial or fungal infection, leading to redness, swelling, and pain in the affected area.
Term
per-
Definition
 Through Example: Percutaneous – Through the skin, often referring to medical procedures such as percutaneous biopsies or drug administration through patches.
Term
pro-
Definition
Before Example: Prodromal – Referring to the early symptoms that occur before a disease becomes fully evident, such as tingling before a herpes outbreak or fever before a rash in measles.
Term
sub-
Definition
Under, below Example: Subcutaneous – Located beneath the skin, as in the subcutaneous fat layer that provides insulation and cushioning to the body.
Term
trans-
Definition
Through, across, beyond Example: Transdermal – Referring to medications applied to the skin that are absorbed into the bloodstream, such as transdermal nicotine patches or hormone replacement therapy.
Term
uni-
Definition
One Example: Unilateral – Pertaining to one side, as in a unilateral skin lesion or rash that affects only one side of the body, often seen in conditions like shingles.
Term
-ad: Toward Example: Cephalad
Definition
Toward the head, commonly used to describe directional movement or anatomical orientation.
Term
-al: Pertaining to Example: Dermal
Definition
Pertaining to the skin, particularly the dermis layer, which contains blood vessels, nerves, and connective tissue.
Term
-coccus: Berry-shaped Example: Staphylococcus 
Definition
A type of berry-shaped bacterium that can cause skin infections such as boils, abscesses, or cellulitis.
Term
-cyte: Cell Example: Melanocyte
Definition
A pigment-producing cell in the skin responsible for producing melanin, which protects against UV radiation.
Term
-ectomy: Excision Example: Lipectomy
Definition
 Surgical removal of fat, often performed for cosmetic reasons or to address localized fat deposits.
Term
-gen: Substance that produces/causes, agent that produces/causes Example: Pathogen
Definition
An agent, such as a bacterium, virus, or fungus, that causes diseases, including skin infections like impetigo.
Term
-genic: Producing, originating, causing Example: Carcinogenic
Definition
 Producing cancer, often describing substances like UV rays or tobacco that can lead to skin or other cancers.
Term
-ia: Condition of, diseased state, abnormal state Example: Alopecia 
Definition
A condition of hair loss that autoimmune diseases, genetic factors, or treatments like chemotherapy can cause.
Term
-itis: Inflammation Example: Dermatitis
Definition
Inflammation of the skin, which may result from allergic reactions, irritants, or infections.
Term
-logist: Specialist who studies and treats Example: Dermatologist
Definition
A medical specialist who diagnoses and treats skin disorders such as acne, eczema, and skin cancer.
Term
-logy: Study of Example: Dermatology
Definition
The study of the skin, including its structure, function, and diseases.
Term
-malacia: Softening Example: Onychomalacia 
Definition
Softening of the nails, which can occur due to fungal infections or malnutrition.
Term
-oid: Resembling Example: Xanthoid
Definition
Resembling yellow, often describing yellowish discolorations of the skin or lesions.
Term
-oma: Tumor, swelling Example: Lipoma
Definition
A benign tumor composed of fatty tissue, often found under the skin.
Term
-opsy: View of, process of viewing, viewing Example: Biopsy
Definition
 The process of removing tissue samples for microscopic examination to diagnose skin cancer or other diseases.
Term
-osis: Abnormal condition, increased numbers pertaining to blood Example: Erythrodermosis
Definition
A condition characterized by widespread redness and peeling of the skin, often linked to disorders such as eczema or psoriasis.
Term
-ous: Pertaining to Example: Sebaceous
Definition
Pertaining to sebum or oil, such as the sebaceous glands that produce skin oil.
Term
-pathy: Disease Example: Dermatopathy
Definition
A disease of the skin, including conditions like psoriasis or eczema.
Term
-plasia: Development, growth, condition of formation Example: Hyperplasia
Definition
 Excessive growth of cells or tissues, which may lead to benign skin growths.
Term
-plasty: Surgical repair Example: Blepharoplasty
Definition
A surgical procedure to repair or reshape the eyelids, often performed to remove excess skin or correct drooping eyelids for functional or cosmetic purposes.
Term
-rrhea: Flow Example: Seborrhea
Definition
Excessive secretion of sebum, leading to oily skin and dandruff.
Term
-rrhage, -rrhagia: Excessive discharge Example: Hemorrhage
Definition
Excessive bleeding, which may occur externally or internally.
Term
-stasis: Stop, controlling, standing Example: Hemostasis
Definition
The stopping of blood flow, critical in wound healing.
Term
-tome: Instrument used to cut Example: Dermatome
Definition
An instrument used to cut thin slices of skin for grafting or diagnostic purposes.
Term
aden/o: Gland Example: Adenoma
Definition
A benign tumor of a gland, often found in areas such as the adrenal glands, sebaceous glands, thyroid, or pituitary gland. These tumors are typically noncancerous but may affect gland function.
Term
adip/o: Fat Example: Adipocyte 
Definition
A fat cell that stores energy in the form of lipids, found primarily in subcutaneous tissue and around internal organs.
Term
albin/o: White Example: Albinism 
Definition

 

A genetic condition characterized by the absence of melanin pigment in the skin, hair, and eyes, leading to increased sensitivity to sunlight and vision issues.

Term
aut/o: Self Example: Autograft 
Definition
A graft of tissue taken from the patient’s own body, often used in burn treatments or reconstructive surgery to minimize rejection.
Term
bi/o: Life Example: Biotherapy
Definition
The use of living organisms or biologically derived treatments to aid in the treatment of skin conditions, such as using probiotics for acne or biologic drugs for psoriasis.
Term
cry/o: Cold Example: Cryotherapy
Definition
A treatment using extreme cold, such as liquid nitrogen, to remove abnormal tissues like warts or precancerous skin lesions.
Term
crypt/o: Hidden Example: Cryptogenic
Definition
A condition or disease of unknown origin, often referring to conditions like cryptogenic cirrhosis or cryptogenic stroke.
Term
cutane/o, derm/o, dermat/o: Skin Example: Dermatitis
Definition
Inflammation of the skin caused by irritants, allergens, or infections, resulting in redness, itching, and swelling.
Term
cyan/o: Blue Example: Cyanosis
Definition
 A bluish discoloration of the skin or mucous membranes due to insufficient oxygen in the blood, commonly seen in respiratory or cardiac conditions.
Term
erythr/o, erythemat/o: Red, redness Example: Erythema
Definition
Redness of the skin caused by increased blood flow to superficial capillaries, often due to irritation, sunburn, or infections.
Term
hidr/o: Sweat Example: Hidrosis
Definition

 

The production and excretion of sweat, which can be excessive (hyperhidrosis) or reduced (anhidrosis), depending on the condition.

Term
kerat/o: Hard, horny tissue, keratin Example: Keratolysis
Definition
A condition characterized by the breakdown or shedding of the outer keratin layer of the skin, commonly seen in conditions like pitted keratolysis, which affects the feet and causes odor and pitting.
Term
lip/o, lipid/o: Fat Example: Lipoatrophy 
Definition
The localized loss of fat tissue beneath the skin, which can occur due to repeated injections, medication use, or underlying medical conditions.
Term
melan/o: Black Example: Melanoma
Definition
A serious type of skin cancer that develops from melanocytes, the pigment-producing cells responsible for skin color, and is often linked to excessive UV exposure.
Term
myc/o: Fungus Example: Mycosis 
Definition
A fungal infection, such as athlete’s foot or ringworm, which can affect the skin, nails, or other body parts.
Term
onych/o, ungu/o: Nail Example: Subungual
Definition
Referring to something located beneath the nail, such as a subungual hematoma, which occurs when blood collects under the nail due to injury or trauma, often causing discoloration and pressure.
Term
pil/o, trich/o: Hair Example: Trichotillomania
Definition
 A psychological condition characterized by an irresistible urge to pull out one’s own hair, often resulting in noticeable hair loss.
Term
xanth/o: Yellow Example: Xanthoma
Definition
  • A yellowish, fatty deposit under the skin, often associated with high cholesterol or lipid disorder

Term

AT = Alopecia Totalis

Definition
  • A rare autoimmune condition characterized by the complete loss of hair on the scalp. The immune system attacks the hair follicles, leading to hair loss. Alopecia totalis is more severe than alopecia areata, which involves patchy hair loss.
Term

BCC = Basal Cell Carcinoma

Definition
  • The most common type of skin cancer that arises from basal cells in the epidermis. BCC grows slowly and rarely spreads (metastasizes) to other parts of the body. It often appears as a pearly or waxy bump, a flat lesion, or a sore that does not heal, typically on sun-exposed areas of the skin.
Term

CD = Contact Dermatitis

Definition
  • An inflammatory skin condition caused by direct contact with an irritant or allergen. Symptoms include redness, itching, swelling, and sometimes blisters. There are two types:

  • Irritant Contact Dermatitis: Caused by substances like soaps or chemicals.

  • Allergic Contact Dermatitis: Caused by allergens like poison ivy or nickel.

Term

I&D = Incision and Drainage; Irrigation and Debridement

Definition
  • Incision and Drainage: A minor surgical procedure used to treat abscesses or infected cysts. It involves making an incision to allow pus or fluid to drain.

  • Irrigation and Debridement: A procedure to clean a wound or infected area by washing (irrigation) and removing damaged tissue or debris (debridement) to promote healing.

Term

MM = Malignant Melanoma

Definition
  • A serious type of skin cancer that develops in the melanocytes, the cells that produce pigment (melanin). It can appear as a new mole or change in an existing mole. MM is aggressive and can metastasize quickly if not treated early. The "ABCDE" rule helps in recognizing melanoma: Asymmetry, Border irregularity, Color variation, Diameter greater than 6mm, and Evolving size, shape, or color.
Term

 

MRSA = Methicillin-Resistant Staphylococcus Aureus

Definition
  • A drug-resistant bacterial infection commonly associated with healthcare settings but also found in the community. It often causes skin and soft tissue infections, which may appear as red, swollen, painful bumps or abscesses. Severe cases can lead to bloodstream infections, pneumonia, or surgical site infections. Prompt treatment with appropriate antibiotics and infection control measures is crucial to prevent complications.
Term

 

NF = Necrotizing Fasciitis

Definition
  • A rare but severe bacterial infection, often referred to as "flesh-eating disease." It destroys skin, fat, and muscle tissues. Symptoms include severe pain, swelling, fever, and skin discoloration. Rapid treatment with antibiotics and surgical removal of infected tissue is critical to prevent life-threatening complications.
Term

 

PDT = Photodynamic Therapy

Definition
  • A treatment that uses light-sensitive medication (photosensitizer) and a specific type of light to destroy abnormal or cancerous cells. PDT is commonly used for skin conditions like actinic keratosis, basal cell carcinoma, and acne. It minimizes damage to surrounding healthy tissue.
Term

 

Ps = Psoriasis

Definition
  • A chronic autoimmune skin condition that causes rapid buildup of skin cells, resulting in scaly patches, redness, and inflammation. Psoriasis often occurs on the scalp, elbows, knees, and lower back. It has several types, including plaque psoriasis (most common), guttate psoriasis, and pustular psoriasis.
Term

 

SCD = Scleroderma

Definition
  • A chronic autoimmune disease characterized by hardening and tightening of the skin and connective tissues. SCD can be localized (affecting only the skin) or systemic (affecting internal organs like the lungs, heart, and kidneys). Symptoms may include skin thickening, Raynaud's phenomenon, and joint pain.
Term

 

SCC = Squamous Cell Carcinoma

Definition
  • A common type of skin cancer that originates in the squamous cells of the epidermis. SCC often develops on sun-exposed areas of the skin, such as the face, ears, and hands. It may appear as a scaly red patch, open sore, or thickened growth. Unlike BCC, SCC is more likely to spread if untreated.
Term

 

SLE = Systemic Lupus Erythematosus

Definition
  • A chronic autoimmune disease that can affect the skin, joints, kidneys, brain, and other organs. In the integumentary system, SLE often causes a butterfly-shaped rash across the cheeks and nose, sensitivity to sunlight, and hair loss. Other symptoms include fatigue, joint pain, and inflammation throughout the body.
Term

 

TEN = Toxic Epidermal Necrolysis

Definition
  • A life-threatening skin condition involving widespread peeling and epidermal detachment, often triggered by severe drug reactions.
Term

 

Kaposi's Sarcoma

Definition
  • Named After: Moritz Kaposi, a Hungarian dermatologist.

A rare form of cancer affecting blood vessels, presenting as purple, red, or brown lesions on the skin and mucous membranes. Commonly associated with HIV/AIDS. Identifying Kaposi’s sarcoma can help in diagnosing underlying immune deficiencies.

Term

 

Langer's Lines

Definition
  • Named After: Karl Langer, an Austrian anatomist.

Natural tension lines in the skin that indicate the direction of underlying collagen fibers. These lines are crucial for surgeons to minimize scarring and optimize healing when making incisions.

Term

Visual Inspection and Dermatoscopy (dermat/o = skin, -scopy = visual examination)

Definition
Healthcare providers use visual inspection as a primary diagnostic tool to evaluate moles, lesions, or discolorations on the skin. Dermatoscopy enhances this process by magnifying and illuminating the skin surface, allowing for a more detailed examination. This method is particularly effective in detecting early signs of melanoma, basal cell carcinoma, and other skin cancers.
Term

Biopsy (bi/o = life, -opsy = view of)

 

Definition

A biopsy involves removing a small sample of tissue for microscopic examination to identify diseases or abnormalities. Several types of biopsies are commonly performed on the integumentary system:

  • Punch biopsy removes a cylindrical core of tissue, useful for diagnosing deeper skin conditions.

  • Shave biopsy removes a superficial lesion, often used for raised or surface-level growths.

  • Excisional biopsy removes an entire lesion, frequently used when skin cancer is suspected.

Term

Wood’s Lamp Examination (Eponym: Named after Robert Williams Wood)

Definition

A Wood’s lamp uses ultraviolet light to highlight abnormalities in the skin. It is particularly effective for diagnosing bacterial or fungal infections and pigmentary disorders. For example, conditions like ringworm or vitiligo can fluoresce under this specialized light, making them easier to identify. This diagnostic tool has become a standard in dermatological evaluations.

 

Term

Microbial Cultures (micro- = small, bi/o = life, -al = pertaining to)

 

Definition

Microbial cultures help isolate and identify bacteria, viruses, or fungi causing skin infections. A sample taken from the skin, nails, or wounds is grown in a lab to detect pathogens. This test is particularly valuable for diagnosing conditions such as impetigo, cellulitis, or fungal infections like athlete’s foot or onychomycosis.

 

Term

Skin Scrapings and Potassium Hydroxide (KOH) Test

 

Definition

Skin scrapings are examined under a microscope after being treated with potassium hydroxide (KOH). This test helps identify fungal elements and is often used to diagnose tinea (ringworm) infections or candidiasis.

 

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