Term
| What is the hallmark of anklyosing spondylitis? |
|
Definition
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|
Term
| What are extra-articular symptoms of ankylosing spondylitis? |
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Definition
Uveitis
Skin Rash
Bowel disease
Aortitis
Apical Pulmonary Scarring |
|
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Term
| What are some additional S&S to help diagnose ankylosing spondylitis? |
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Definition
Elevated ESR or CRP
+HLA B-27
Diminished chest excursion
Limited spinal ROM + Schober’s test |
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Term
| What is seen on oblique x-ray with AS? |
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Definition
Sclerosis on SI joints
Syndesmophytes
Bamboo spine |
|
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Term
| What is the best treatment for AS? |
|
Definition
|
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Term
| What comes first: the skin diseases or joint disease in psoriatic arthritis? |
|
Definition
|
|
Term
| How will psoriatic arthritis present? |
|
Definition
| One or more of: fatigue, tenderness, pain and swelling over tendons; swollen fingers and toes; stiffness, pain, throbbing, swelling and tenderness in one or more joints; reduced ROM, morning stiffness and tiredness, nail changes, redness and pain of the eye |
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Term
| What are the subtypes of psoriatic arthritis? |
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Definition
Asymmetric olioarthritis with dactylitis
RA-like polyarthritis
Distal interphalangeal
Spondylitis
Arthritis Multilans
HIV related |
|
|
Term
| How can psoriatic arthritis mimic RA? |
|
Definition
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|
Term
| What deformity can be seen on x-ray with psoriatic arthritis? |
|
Definition
| Pencil in cup – bone erosions at the distanl phalanx |
|
|
Term
| What test should you get in a male with new onset psoriatic arthritis? |
|
Definition
|
|
Term
| What meds are used to treat psoriatic arthritis? |
|
Definition
NSAIDs (can make skin worse)
DMARDs – MTX
Biologics – TNF inhibitors |
|
|
Term
| What is the triad of sx for Reiter’s syndrome? |
|
Definition
Oligoarthritis
Urethritis
Conjunctivitis |
|
|
Term
| In general, how does reiter’s syndrome present? |
|
Definition
| Lesions of the skin and mucous membranes |
|
|
Term
| What tests do you do for Reiter’s syndrome? |
|
Definition
Joint and SI x-ray
U/A
Urethral/cervical swab for Chlamydia
Stool culture
HLA-B27
HIV |
|
|
Term
| What are the characteristics of Parvovirus B19? |
|
Definition
Transient generalized rash
Small joint swelling – usually symmetrical
Resolves in 2-4 weeks
IgM parvovirus titers positive
Non-erosive |
|
|
Term
| What can Enteropathic arthropathies be linked to? |
|
Definition
Inflammatory bowel disease (IBD)
Bacteria
Parasites
Other GI pathologies |
|
|
Term
| What is the treatment of IBD? |
|
Definition
| Surgery – alleviates the pain of peripheral arthritis |
|
|
Term
| What may be helpful in enteropathic arthropathies to treat peripheral sx? |
|
Definition
|
|
Term
| What is another group of medicine that is FDA approved for IBD and arthritis? |
|
Definition
|
|
Term
| Which type of cartilage lines joints? |
|
Definition
|
|
Term
| Which type of cartilage forms syndesmoses like the pubic synthesis? |
|
Definition
|
|
Term
| Which type of cartilage is found in the ligamentum nuchae of the C-spine? |
|
Definition
|
|
Term
| When do alk phos levels rise? |
|
Definition
|
|
Term
| What is the chief structural component of bone? |
|
Definition
|
|
Term
| Where does osteoarthritis "attack"? |
|
Definition
| attacks the cartilage than works its way out |
|
|
Term
| Where does avascular necrosis "attack"? |
|
Definition
|
|
Term
| What is the function of the synovial membrane? |
|
Definition
|
|
Term
|
Definition
| targets the synovium and works its way into the joint space |
|
|
Term
|
Definition
| where the tendon attaches to the bone |
|
|
Term
| What disease attacks the enthesis? |
|
Definition
|
|
Term
| Which type of joint has no movement? What are some examples? |
|
Definition
Fibrous (Synarthroidial)
Examples - Cranium, Distal Tib/Fib |
|
|
Term
| Which type of joint has minimal movement? What are some examples? |
|
Definition
Cartilignous (amphiarthroidial)
Costochondral joints, pubic synthesis, spine |
|
|
Term
| Which type of joint is freely movable? |
|
Definition
|
|
Term
| What are the type of crystals found in gout? |
|
Definition
| Monosodium urate, needle-like negatively (yellow) birefringent |
|
|
Term
| What type of crystals are found in pseudogout? |
|
Definition
| Calcium pyrophosphate (short, rhomboid positively blue birefringent) |
|
|
Term
| Which fluid type appears yellow, clear, and has a cell count of 200 - 2,000? |
|
Definition
|
|
Term
| Which type of joint fluid is yellow, cloudy, and has a cell count of 2,000 - 75,000? |
|
Definition
|
|
Term
| What type of joint aspirate is described as purulent, opaque, has a cell count of greater than 60,000 and has greater than 80% of PMN? |
|
Definition
|
|
Term
| What type of diseases can cause Non-Inflammatory Type I joint aspirate? |
|
Definition
Osteoarthritis
Trauma
Osteonecrosis
SLE |
|
|
Term
| What type of diseases can cause Inflammatory Type II joint aspirate? |
|
Definition
RA
Reiter's Syndrome
Crystal Arthritis
SLE
Viral Arthritis
Fungal Arthritis
TB Arthritis |
|
|
Term
| What type of diseases can cause Septic Type III joint aspirate? |
|
Definition
Bacterial Arthritis
Crystal Arthritis |
|
|
Term
| What are some causes of Hemorrhagic Type IV joint aspirate? |
|
Definition
Trauma
Fracture
Ligament Tear
Hemophilia
Charcot Arthritis
PVNS |
|
|
Term
| What is Anti-CCP a predictor of? |
|
Definition
| Excellent predictor of RA |
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