Term
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Definition
Testosterone
TC: Anti-hypotestosteronemia
PC: Androgen receptor agonist
CC: Androgen |
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Term
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Definition
Dutasteride (Avodart)
TC: 5a-reductase inhibitor
CC: 4-azasteroid
Blocks both Type I and II 5AR
Targets Static Component of BPH |
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Term
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Definition
Finasteride (Proscar, propecia)
TC; 5a-reductase inhibitors
CC:4-azasteroid
Blocks Type II 5AR
Targets the static components of BPH |
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Term
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Definition
Tamulosin (Flomax)
TC:a1-receptor antagonist
CC: Quinazoline core
Targets the dynamic component of BPH (smooth muscle contraction) |
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Term
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Definition
Sildenafil (Viagra)
TC:PDE5 Inhibitors
CC:pyrazolopyrimidinone core
AE:visual and hearing problems
CX: in patients taking nitrates |
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Term
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Definition
Estradiol (Estrace)
TC:HRT
PC: Estrogen receptor agonist
CC: Steroid |
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Term
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Definition
Ethinyl Estradiol (Estinyl)
TC: Contraceptive Agent
PC: Estrogen receptor agonist
CC: Steroid |
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Term
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Definition
Tamoxifen (Novaldex)
TC: Anti-cancer agent
PC: SERM
CC: Triphenylethylene |
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Term
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Definition
Clomiphene (Clomid)
TC: Profertility (Pro-ovulation)
PC: SERM
CC; Triphenylethylene |
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Term
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Definition
Medroxyprogesterone (provera)
TC: Contraceptive, Anti-endomitriosis agent
PC: Progesterone receptor agonist
CC: Steroid |
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Term
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Definition
Mifepristone (RU, Mifeprex)
TC: Termination of Pregnancy; abortifacient
PC: Glucocorticoid and Progesterone receptor antagonist
CC: Steroid |
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Term
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Definition
Leuprolide (Lupron)
TC: Anti-endometriosis agent
PC: GNRH receptor agonist
CC: Octa-peptide |
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Term
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Definition
Nabilone (cesamet)
TC: Antiemetic
PC: Agonism at CB1 receptors in CTZ
CC: Cannabinoid
Indicated for: CINV
CII controlled |
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Term
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Definition
Scopalamine (Trans-derm scop)
TC: Antiemetic Transdermal
PC: Muscarinic receptor antagonist
CC: Tropane
Indicated for: Motion sickness, PONV |
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Term
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Definition
Prochlorperazine (Compazine)
TC: Antiemetic
PC: Dopamine antagonist
CC: Phenothiazine
Indicated in: Severe N/V |
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Term
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Definition
Promethazine (Phenergan)
TC: Antiemetic
PC: Histamine receptor antagonist
CC: Phenothiazine
Indicated for: Motion sickness |
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Term
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Definition
Meclizine (Bonine, antivert)
TC; Antiemetic
PC: Histamine receptor antagonist
CC: Piperazine
Indicated for: Motion sickness
OTC |
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Term
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Definition
Aprepitant (Emend)
TC: Anti-emetic
PC: Neurokinin 1 antagonist/ Substance P
CC: Morpholine
Indicated for: Acute and delayed CINV, PONV |
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Term
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Definition
Ondasetron (Zofran)
TC: Antiemetic
PC: 5HT3 receptor antagonist
CC: Indole
Indicated for: PONV, CINV and other |
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Term
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Definition
Ranitidine (Zantac)
TC: Anti-ulcer agent
PC: H2 Receptor antagonist
CC: varied |
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Term
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Definition
Omeprazole (Prilosec)
TC: Anti-ulcer/ Anti-dyspepsia agent
PC: PPI
CC: benzimidazole
Sterochemistry with the lone pairs on the Sulfoxide |
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