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med micro bio epidemiology terms
terms and definitions
28
Microbiology
Graduate
07/04/2012

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Term
endemic
Definition
continuous presence of disease- low level
Term
epidemic
Definition
larger than normal # of cases by a single agent in a specific geo area w/in a short time period
Term
pandemic
Definition
worldwide epidemic
Term
morbidity
Definition
rate- incidence of disease
Term
incidence
Definition
%: #new cases/total population (specific time interval)
Term
prevalence
Definition
%= total # of cases/total population (cumulative)
Term
mortality
Definition
rate- death from disease
Term
reservoir
Definition
source of infection
Term
kinds of reservoirs
Definition
human, bio vectors, soil, water, nosocomial infections
Term
epidemiology
Definition
study of the factors influencing frequency and distribution of disease
Term
human reservoir
Definition
1- incubation period
2- carriers
Term
human carriers-
Definition
organism retained in body (+/- shedding in body fluids.
1-normal flora
2-persistent infection (latent and chronic)
Term
latent infection
Definition
organism hides in host cell, not easily spread
Term
chronic infection
Definition
organism in body fluids, more easily spread
Term
zoonoses
Definition
animal infecting humans
Term
biological vectors
Definition
part of life cycle of microbe)
1- animals
2- arthropods (ticks, fleas, mosquitos)
Term
modes of transmission
Definition
1-portal of entry
2-direct contact
3-indirect contact
Term
portal of entry
Definition
site where microbe/toxin enters body
1- skin via cut/abrasion
2- mucus membranes- resp. tract, GI tract, genital tract, urinary tract
Term
direct contact (mode of transmission)
Definition
inhalation, contact w/saliva, sex, child birth, in utero (vertical transmission), bite(animal/human), transplant of infected organ
Term
indirect contact (mode of transmission)
Definition
1- inhale contaminated air
2- mechanical vector
3- contact with fomites
4- contaminated fingers
5-ingestion of contaminated food/water (vehicle)
6- injection w/ blood from infected person
Term
contaminated air
Definition
contains droplet nuclei (human), environmental aerosol, aerosol- animal source
Term
mechanical vector
Definition
living being that caries pathogen on body ( not part of microbe life cycle)
Term
factors influencing character of epidemic
Definition
level of immunity in population, environmental conditions, cultural customs, virulence of strain, intensity of exposure
Term
intensity of exposure
Definition
1- high dose: overwhelm immune host
2- low dose: increase # of infected persons, longer incubation period, asymptomatic infection
Term
control of epidemic
Definition
increase host resistance, reduce reservoir/vectors, segregation/isolate/quarantine, medical & surgical asepsis in hospitals
Term
increase host resistance
Definition
vaccination, herd immunity
passive immunity (IG)
drug prophylaxis
Term
medical & surgical asepsis in hospitals
Definition
decrease nosocomial infection
Term
epidemiologic typing
Definition
determine if all cases are due to same strain/source
pulsed-field gel electrophoresis
antibiograms
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