Term
| General Treatment for Treponema pallidum (Syphilis)? |
|
Definition
| Penicillin and tetracyclines (resistance to erythromycin and other macrolides has appeared) |
|
|
Term
| What is the major determinant of the duration and dose of treatment for syphilis (T pallidum)? |
|
Definition
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Term
| Treatment for Neurosyphilis? |
|
Definition
| penicillin or ceftriaxone (IV or IM) for 10-14 days |
|
|
Term
| Treatment for Primary, secondary, and early latent syphilis in adults without neurologic involvement? |
|
Definition
Benzathine penicillin G in single IM dose
if penicillin allergic: an oral tetracycline each day for 2 weeks |
|
|
Term
| Treatment for Late latent and tertiary syphilis? |
|
Definition
benzathine penicillin IM (1 a week for 3 weeks)
or an oral tetracycline (each day for 4 weeks) |
|
|
Term
| Treatment for Jarisch-Herxheimer (J-H) reaction? |
|
Definition
| self limiting, no treatment (JH can occur after antibiotic treatment) |
|
|
Term
| Treatment for non-venereal treponematoses (T. caraeum [pinta], T. pallidum pertenue [yaws] and endemicum) |
|
Definition
| benzathine penicillin; single dose (Individual & mass treatment) |
|
|
Term
| Treatment for Leptospira interrogans? |
|
Definition
| tetracyclines or penicillins; J-H reaction may occur. |
|
|
Term
| Treatment for Borrelia recurrentism (relapsing fever)? |
|
Definition
| oral penicillin or tetracycline |
|
|
Term
| Treatment for Lyme disease (Borrelia burgdorferi)? |
|
Definition
Early: Oral tetracycline or beta-lactam antibiotic
Late disease: also oral
If CNS involvement then IV beta-lactam antibiotic is given |
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