Term
| AZT (Zidovudine) 200mg tid |
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Definition
| HIV Reverse transcriptase inhibitor. Inhibits the enzyme reverse transcriptase which HIV uses to copy it’s RNA into DNA. Side effects include anemia, neutropenia, nausea, malaise, headache, insomnia, myopathy. Therapist should monitor pt. for feelings of tiredness, nausea, headaches, or feeling “out of sorts”. Therapist should be aware that pt. may not be sleeping well. |
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Term
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Definition
| HIV Non-nucleoside reverse transcriptase inhibitor (NNRTI) that inhibits the enzyme reverse transcriptase which HIV uses to copy it’s RNA into DNA. Pt. may have abdominal cramps, fever, edema and other side effects from the medication. Abnormal cardiac rate and rhythm may occur along with hypertension and other cardiovascular side effects. The therapist should be aware of these side effects and explain to the pt. what red flag symptoms to look for and continuously monitor the pt. for discomfort and indications to stop exercise. |
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Term
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Definition
| HIV Inhibitor of HIV protease, which is the enzyme required for proteolytic cleavage of viral polyprotein precursors. It binds to the protease active site to inhibit the enzyme activity. Pt. may experience side effects of diarrhea, nausea, dyspepsia, and abdominal pain. In order to make therapy safe and effective, therapist should be aware of these side effects and continuously monitor pt. for any indication of discomfort. |
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Term
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Definition
| UTI Inhibits the synthesis of folic acid by interfering with dihydrofolate reductase Side effects of this medication can include fever, nausea, vomiting, and skin rash. The therapist must be aware of these side effects and monitor the patient for any changes. Checking the skin for any signs of a developing rash is important since the patient is bed bound and unable to move on his own. |
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Term
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Definition
| Leprosy and bacterial skin infections In the class of chemical agents called sulfones. It is an antibacterial drug that impairs folic acid synthesis by competing with PABA in the bacterial cells. Side effects include peripheral motor weakness, rash, itching, fever, and blood dyscrasis. Therapist should be examine the skin for any evidence of rash or adverse reaction. Therapist should be aware of the side effects and monitor pt. for feelings of tiredness or fever. |
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Term
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Definition
| Pain/ feverStimulation of opioid receptors in the brain. Side effects can include drowsiness, dizziness, nausea, vomiting, constipation, abdominal pain, skin rashes, lightheadedness, headache, weakness, hallucinations, minor visual disturbances, feelings of elation or discomfort. |
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Term
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Definition
Fluconazole
100 mg qd Esophogeal Candidiasis Inhibits the fungal cytochrome P450 enzyme which is responsible for fungal sterol synthesis to weaken the fungal cell walls. Side effects can include headaches, dizziness, nausea, vomiting, abdominal pain, diarrhea, and skin rash. Therefore, the therapist should be aware of and monitor for these symptoms, especially during exercise. The therapist must be receptive to patient complaints and modify activities as necessary. |
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Term
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Definition
| Blood Thinner Inhibits vitamin K-dependent activation of clotting factors formed in the liver. Skin breakdown will involve increased bleeding with difficulty clotting. Other side effects can include heachache, fever, anorexia, nausea, vomiting, cramps, diarrhea, mouth ulceration, sore mouth, dermatitis, necrosis, gangrene, rash, |
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Term
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Definition
| (PLetal) Cilostazol is used to reduce the symptoms of intermittent claudication (pain in the legs that happens when walking and goes away with rest). Cilostazol helps people walk a longer distance before leg pain starts. |
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Term
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Definition
(Pentoxil®
Trental®)Pentoxifylline is used to improve blood flow in patients with circulation problems to reduce aching, cramping, and tiredness in the hands and feet. It works by decreasing the thickness (viscosity) of blood. This change allows your blood to flow more easily, especially in the small blood vessels of the hands and feet. |
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Term
| Warfarin, Coumadin, Heparin |
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Definition
| blood thinners, Heparin is usually in IV form. Coumadin or Warfarin are a regimen taken once returning home. |
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