Term
|
Definition
Terazosin /
Alpha 1 Antagonist /
Anti-HTN /
Structure: Quinazoline |
|
|
Term
|
Definition
Clonidine
/ Alpha 2 Agonist (Central Acting)
/ Anti-HTN
/ Structure:Imidazoline |
|
|
Term
|
Definition
Propranolol
/ Non-selective Beta Antagonist w/o ISA
/ Anti-HTN
/ Structure: Aryloxypropranolamines |
|
|
Term
|
Definition
Pindolol /
Non-selective Beta antagonist with ISA /
Anti-HTN /
Structure: Aryloxypropranolamine |
|
|
Term
|
Definition
Atenolol /
Cardioselective Beta Antagonist /
Anti-HTN /
Structure: Aryloxypropranolamine |
|
|
Term
|
Definition
Metoprolol /
Cardioselective Beta Antagonist /
Anti-HTN /
Structure: Aryloxypropranolamine |
|
|
Term
|
Definition
Carvedilol /
Mixed Alpha Beta antagonist /
Anti-HTN /
Structure: Aryloxypropanolamine and phenylethanolamine |
|
|
Term
|
Definition
| Diltiazem / 1st generation CCB Benzothiazepines / Cis-arrangement of phenyl and acetyl required for activity |
|
|
Term
|
Definition
| Verapamil / 1st generation CCB Phenylalkylamines / S- stereoisomer more potent |
|
|
Term
|
Definition
| Amlodipine / 3rd generation CCB Dihydropyridine / 1-4 dihydropyridine required for activity |
|
|
Term
|
Definition
| Sildenafil / PDE-5 Inhibitor / Vasodilation in PAH / Also used in Erectile Dysfunction |
|
|
Term
|
Definition
| Bosentan / Endothelin Antagonist / Nonselective for ETA and ETB / Used for vasodilation in PAH |
|
|
Term
|
Definition
| Epoprostenol / Prostacyclin Receptor Agonist / Vasodilator in PAH / Short half life |
|
|
Term
|
Definition
| Aliskiren / Renin Inhibitor / Inhibits the aspartyl protease |
|
|
Term
|
Definition
| Enalapril / ACEI / Zinc binding group is a Dicarboxylate / Acidic H accepting group |
|
|
Term
|
Definition
| Losartan / ARB / Active metabolite |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Furosemide / Loop Diuretic |
|
|
Term
|
Definition
| Oxybutynin / AntiMuscarinic for OAB and UI |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Triamterene / Potassium Sparing Diuretic / Sodium channel Inhibitor |
|
|
