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Definition
| cell coat of carbohydrates on surface |
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Definition
phospholipids
glycolipids
cholesterol |
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Term
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Definition
| Transmembrane & peripheral |
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Definition
| hydrophobic and hydrophilic parts |
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Definition
| most abundant 1 hydrophilic 2 hydrophobic |
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Definition
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Definition
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Definition
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| Leaflets are held together via ____ |
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Definition
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Term
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Definition
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Term
| Fluidity 3 factors and how affects |
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Definition
Cis bonds increase
temperture increase
cholesterol decrease |
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Term
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Definition
associated with chronic liver disease
aka spur cells
xs cholesterol transferred to outer leaflet
to decrease deformability sequenstration & destruction by spleen ---> haemolytic anemia |
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Term
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Definition
rich in cholesterol & glycosphingolipids
contain integral & peripheral membrane proteins
GPI: glycosylphophatidylinositol anchor |
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Term
| Asymmetry of membrane is maintained by |
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Definition
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Term
| Flip flop requires 2 things |
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Definition
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Term
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Definition
integral - 30 % total protein AMPHIPATHIC
peripheral
lipid |
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Term
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Definition
| spectrin linked into junctional complex |
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Definition
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Definition
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Definition
| multipass transmembrane protein |
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Term
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Definition
| spectrin ankyrin or protein 4.1 problems |
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Term
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Definition
glycoproteins
glycolipids - only outer leaflet
proteoglycans |
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Term
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Definition
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Term
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Definition
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Term
| Phosphatidyl serine does what |
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Definition
| serine flipped to outer leaflet signals apoptosis |
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Term
| Glycosylphosphatidylinositol (GPI) does what |
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Definition
| anchors link proteins to outer leaflet |
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Term
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Definition
| fatty acylation or prenylation link proteins to inner leaflet |
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Term
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Definition
single lipid bilayer
CONTINUOUS WITH NUCLEUR MEMBRANE |
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Term
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Definition
continous with rough ER
no ribosome |
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Term
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Definition
| PROTEIN production for ER, Golgi, endosomes, plasma membrane, & secretion |
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Term
| why is rER prominent in secretory cells |
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Definition
| b/c secretory cells need to make lots of protein products |
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Term
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Definition
lipids steroids detox
also release of sequestration oc Ca++ during muscle contraction |
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Term
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Definition
| on proteins directs ribosomes to ER membrane |
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Term
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Definition
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Definition
| transport into other organelles |
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Term
| what initiates transloacation |
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Definition
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Term
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Definition
assembled and transferred to polypeptide by dolichol membrane bound lipid
n linked glycosylation |
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Term
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Definition
| sugars attached to oh of selected serine or threonine residues |
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Term
| cytosolic ubiquitin attached to misfolded protein causes |
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Definition
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Term
| Non bound proteosomal degradation = |
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Definition
| non lysosomal protein degradation |
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Term
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Definition
club fingers
sweat test
mutation in CFTR
predominate mutation (F508) --> incorrectly folded protein |
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Term
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Definition
LDL receptor
xanthomata
corneal arcus
xanthelasamata
major risk for CHD
premature atherosclerosis |
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