Term
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Definition
| Inflammatory cytokines produced by macrophages (3) |
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Term
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Definition
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Term
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Definition
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Term
| IL-2, TNF-alpha, TNF-gamma |
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Definition
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Term
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Definition
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Term
| Activate macrophages, CTL's |
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Definition
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Term
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Definition
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Term
| Perforin/Granzyme B, Fas-Fas Ligand |
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Definition
| CTL's two pathways to kill |
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Term
|
Definition
| Class I MHC molecule alleles |
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Term
|
Definition
| Class II MHC molecule alleles |
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Term
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Definition
| When ab blocks a molecule on pathogen surface that prevents in from entry into host cells |
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Term
|
Definition
| When ab enhances phagocytosis |
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Term
| Antibody-dependent cell-mediated cytotoxicity |
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Definition
| When ab enables cells of the immune system to kill off infected cells |
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Term
| Size, antigen dose, complexity |
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Definition
| Factors that make a good immunogen (3) |
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Term
| 3-d peptides, carbohydrates, lipids |
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Definition
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Term
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Definition
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Term
|
Definition
| Increase in diameter of blood vessels |
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Term
|
Definition
| Increased capillary permeability for more passage of fluid and cells |
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Term
| Oxygen radicals and enzymes |
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Definition
| Molecular mediators released from granules by neutrophils |
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Term
|
Definition
| The "danger signal" of the immune response |
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Term
|
Definition
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Term
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Definition
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Term
| Neutrophils, Basophils, Eosinophils, Mast Cells |
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Definition
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|
Term
| macrophages, dendritic cells |
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Definition
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Term
| T-cells, B-cells, NK cells |
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Definition
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Term
| DNA (transcription) to RNA (translation) to protein |
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Definition
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Term
|
Definition
| Proteins that bind receptors |
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Term
|
Definition
| Proteins on cell surface that can bind to trigger endocytosis |
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Term
|
Definition
| When multiple receptors bind multiple ligands |
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Term
|
Definition
| Immune hormones, messengers that control and regulate the immune system |
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Term
|
Definition
| This class of MHC is only expressed on APC's |
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Term
| Cleft/peptide binding groove |
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Definition
| Where antigen binds to the MHC molecule |
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Term
|
Definition
| Organelle where viral proteins are digested into peptides |
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Term
|
Definition
| Signals that inhibit viral replication inside cell |
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Term
|
Definition
| This is required for virus latency |
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Term
|
Definition
| Ag binding portion of ab molecule |
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Term
|
Definition
| Where the antibodies can react with other immune cells to activate pathogen killing |
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Term
|
Definition
| Memory ab isotype, is a monomer |
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Term
|
Definition
| First antibody made against infection, is a pentamer |
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Term
|
Definition
| Universal blood recipient |
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Term
|
Definition
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Term
|
Definition
| Immune cells that haven't encountered antigen |
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Term
|
Definition
| Immune cells that have been activated |
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Term
|
Definition
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Term
|
Definition
| Multiple functional forms of same gene |
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Term
|
Definition
| identical at all MHC loci |
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Term
|
Definition
| DIfferent at MHC different alleles |
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Term
|
Definition
| Weakened or slow immune response |
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Term
|
Definition
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Term
|
Definition
| Replicating organisms that can cause harm or disease |
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Term
|
Definition
| Any molecule that the immune system responds to |
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Term
|
Definition
| The acute phase response acts results from inflammatory cytokines acting on this organ |
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Term
|
Definition
| Complexes of molecules containing antigens that when injected, elicit the adaptive immune response |
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Term
|
Definition
| Order of isotype switching, is irreversible |
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Term
| Activation, proliferation, differentiation |
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Definition
| 3 stages of B and T cells |
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Term
|
Definition
| T cells will only recognize antigens presented by own MHC molecules |
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Term
|
Definition
| T cells only recognize one unique antigen presented on their own MHC |
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Term
| Biologic response gradient |
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Definition
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Term
|
Definition
| Another organism or object that helps in transfer of disease |
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Term
|
Definition
| Infectious agents that are primarily transmitted between animals but can infect humans |
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Term
|
Definition
| Transmission from person to person |
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Term
|
Definition
| Transmission from parent to offspring |
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Term
|
Definition
| Control the initial activation of naive T cells in lymph nodes and spleen |
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Term
|
Definition
| Exogenous pathogens are presented on this MHC |
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Term
|
Definition
| Endogenous pathogens are presented on this MHC |
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Term
|
Definition
| Viruses are selective for infecting certain cells |
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Term
|
Definition
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|
Term
| Mutation, antigenic variants, latency, immunological inhibitors, immune privileged cells |
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Definition
| Viral responses to evade immune system |
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Term
| Coronaviruses, rhinoviruses, polio, influenza, rabies, measles |
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Definition
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|
Term
| Hepatitis B Virus, Epstein Barr Virus, Herpes Simplex Virus, Varicella Zoster Virus |
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Definition
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|
Term
| Smaller size and genome, fewer proteins, fast growth and replication, often lytic |
|
Definition
| Characteristics of RNA viruses |
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|
Term
| Larger genome, DNA integration for latency, oncogenic |
|
Definition
| Characteristics of DNA viruses |
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