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| Any detectable, heritable variation in the lineage of germ cells. Mutations in these cells are transmitted to offspring. Permanent changes to the DNA are passed on to subsequent generations |
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| A mutation in the somatic cell. These mutations do not get passed down to offspring. |
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| A group of cancers derived from epithelial cells. |
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| The spread of cancer from its primary site to other places in the body. |
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| This is programmed cell death that occurs after the cell has decided that it is abnormal. Apoptosis is ignored when cells become cancerous. |
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| Breast cancer that is more rare than ductal carcinoma and starts in the lobules of the mammary glands. |
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| Breast cancer that starts in the epithelial cells of the breast. |
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| The series of events that take place in an eukaryotic cell between its formation and the moment it replicates itself. These events can be divided in two main parts: interphase (in between divisions phase grouping G1 phase, S phase, G2 phase), during which the cell is forming and carries on with its normal metabolic functions; the mitotic phase (M mitosis), during which the cell is replicating itself. Thus, cell-division cycle is an essential process by which a single-cell fertilized egg develops into a mature organism. |
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Definition
Checkpoints ensure the cell cycle
proceeds without errors. If there is an
unfavorable extra-cellular environment and
damaged DNA, it must be repaired before it
transitions between G1 and S. There is a
check to see if DNA is incompletely
replicated or is damaged before it goes into
mitosis. |
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