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MCB 2410 Chapter 10
for exam 2
12
Biology
Undergraduate 1
03/30/2011

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Term
Griffith's experiment
Definition
demonstrates the principle of TRANSFORMATION; rough nonvirulent (type R) versus smooth virulent (type S); Genetic information from the heat-killed S cells was transferred to the R cells, transforming them to virulence
Term
Avery, MacLeod and McCarty
Definition
Isolated components from heat-killed S; ONLY DNA HAD THE ABILITY TO TRANSFORM
Term
Hershey and Chase
Definition
T4 bacteriophage viruses with radioactive sulfur in protein coat and radioactive phosphorus in DNA
Term
hereditary material characteristics
Definition
1) CHEMICAL STABILITY AND GENETIC STABILITY (FAITHFUL COPIES)

2) STORAGE OF GREAT AMOUNT OF INFORMATION (CODE FOR ALL TRAITS)

3) POTENTIAL FOR CHANGE (MUTATION)
Term
structure of DNA
Definition
sugar (deoxyribose), phosphate group, nitrogenous base
Term
purine
Definition
adenine and guanine; TWO rings
Term
pyrimidine
Definition
cytosine and thymine; ONE ring
Term
Chargaff
Definition
base pairing; 1:1 ratio of pyrimidine and purine bases in double stranded DNA
Term
A-T # of hydrogen bonds
Definition
TWO
Term
C-G # of hydrogen bonds
Definition
THREE
Term
phosphodiester bond
Definition
covalent bonds between deoxyribose 5' phosphate and 3' hydroxyl group
Term
Central Dogma
Definition
information flows from DNA TO RNA (translation) to protein (transcription)
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