Term
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Definition
| -Δ G, spontaneous at all temps |
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Term
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Definition
| +Δ G, non-spontaneous at all temps |
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Term
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Definition
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Term
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Definition
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Term
| if delta G is negative what does it tell you about energy and speed of rxn |
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Definition
exothermic
cannot tell anything about how fast rxn is, |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Eqn for Gibbs free energy |
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Definition
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Term
| Gibs energy eqn std in a cell where molarities arent 1 |
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Definition
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Term
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Definition
| lowers Ea in both directions by stabilizing Transition state |
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Term
| what does catalyst do to equilibrium |
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Definition
| does not shift/mess with it |
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Term
| higher Km means -- substrate |
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Definition
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Term
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Definition
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Term
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Definition
| inhibitor binds to active site |
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Term
| competitive inhibition effect on Km and Vmax |
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Definition
increases Km
doesn't change Vmax |
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Term
| Non-competitive inhibition |
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Definition
| inhibitor binds not at active site |
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Term
| non- competitive inhibition effect on Km and Vmax |
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Definition
Km does not change
Vmax is lowered |
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Term
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Definition
| binding of one substrate increases affinity for the next substrate to bind |
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Term
| cooperativity has a -- curve |
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Definition
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Term
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Definition
| Hb has 4, where Mb (muscle) only has 1 subunit and therefore Mb does not have cooperativity |
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Term
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Definition
| prescence of H+ and CO2 decrease Hb affinity for O2 causing Hb to release O2 in the tissue. This shifts the sigmoid curve to the right |
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Term
| Pressure of O2 is highest in |
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Definition
| lungs, causing the high % saturation of Hb to pick it up and deliver to tissue where PO2 is lower to release it |
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Term
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Definition
| not active site, feedback inhibition |
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Term
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Definition
| covalent modification by adding a phosphate it adds - charge |
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Term
| AA with an OH group that can be phosphorylated |
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Definition
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Term
| Kinases or phophorylations |
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Definition
add phosphate
kinase- ATP hydrolysis |
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Term
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Definition
| dephosphorylate enzymes, take phosphate off |
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Term
| what does phosphorylation do to the enzyme |
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Definition
| changes the confirmation, either activating it or deactivating it. |
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Term
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Definition
inactive precursors that become active w/proteolytic cleavage
ex: digestive enzymes trypsin and chymotrypsin |
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Term
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Definition
| enzyme regulation with the use of metal ions or coenzymes |
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