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MCAT bio*6
euk cell
46
Biology
Undergraduate 4
05/04/2014

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Term
rough ER
Definition
synthesis and glycosylation of peptides to form glycoproteins destined for secretion or integration into membrane
Term
smooth ER
Definition
synthesis of lupids and hormones exported from cell
breaks toxins in liver
Term
golgi aparatus
Definition
modification and packaging of proteins into vesicles for secretion or transport to cell destination
Term
mitochondria
Definition
site of ATP synthesis via ATP synthase
site of fatty acid cataboilism B-ox
has own DNA and ribosomes
Term
lysosomes
Definition
contains acid hydrolases (digestive enzymes)
pH5- not active in cytoplasm
degrades old cell material
produced from golgi, not in plants
Term
peroxisomes
Definition
involved in breakdown (involved in hydrogen peroxide) of many substances: FA, AA, toxins
carry out glyoaxalate cycle in germinating plant seeds
Term
centrioles
Definition
spindle apparatus for cell division
not in plants
Term
vacuoles
Definition
used for transport, storage,
plants- cell rigidity
Term
plant vs animal cells
Definition
animals- lysosomes, centrioles
plants- cell walls, chloroplasts, central vacuole
Term
cell wall made of:
-bacteria
-archae
-fungi
-plant
-animal
Definition
bacteria- peptidoglycan
archae- polysaccharides
fungi- chitin
plant- cellulose
animal- none
Term
SRP protein trafficking
Definition
signal peptide on the polypeptide chain binds with the SRP (signal recognition particle) this stalls translation and the ribsosome and polypeptide still attached goes to rough ER.
SRP directs ribsomse to implant into ER membrane and the peptide chain is threaded thru. Translation resumes and peptide is cleaved.
Peptide leaves in vacuole. Enters cis side of goldi, leaves trans side.
Term
plasma membrane
Definition
phosphlipids, glycolipds, cholesterol (rigidity)
unsaturated FA increase membrane fluidity
Term
periperal membrane
Definition
membrane surface
Term
integral membrane proteins
Definition
embedded in membrane
Term
transmembrane proteins
Definition
spans membrane and includes channel proteins, carrier proteis, porins
Term
cell receptors
Definition
regonition of glycoproteins on cell surface that interact w/hormones or other molecules to relay signals to cell
Term
gap junction
Definition
allow exchange of nutrients and cell-to-cell communication (cardiac)
Term
tight junction
Definition
completely encircles cells and seals the space btw them to prevent leakage (intestinal)
Term
desmosomes
Definition
spot welds- btw cells that adhere them to one anoher and give mechanical strength, anchored to cytoskeletons of each cell (skin)
Term
glocalyx
Definition
carb caoating on cell wall of some bacteria and the plasma membrane of some animals, for adhesion, barrier to infection, cell-cell recognition
Term
passive transport
Definition
diffusion
Term
facilitated diffusion
Definition
diffusion via carrier protein/channel
Term
Membrane transport of:
CO2, O2, lipids, glucose, Na, K+,
Definition
simple diffusion-CO2, O2, lipids
fac. diffusion- glucose
primary active transport: Na, K
Term
Active transport
Definition
works against the conc. gradient req. ATP energy
Term
primary active transport
Definition
Na/K pump fueled directly by ATP
Term
secondary active transport
Definition
uses one solutes gradient (est. by ATP) to accomplish the transport of another (Na+/glucose cotransport)
Term
Na+/ K+ in cell
Definition
K+ high in
Na+ high out
Term
Na/K pump
Definition
3Na+ pumped out and 2K+ pumped into cell to generate resting membrane potential
Term
cell signaling via G-proteins
Definition
1.ligand binds to G-protein receptor
2. G-protein receptor activates G-protein which binds GTP
3. G-protein activated adenylate cyclase (atp->cAMP)
4. cAMP acts as "2nd msnger" activated series or proteins/transcription factors
Term
hypotonic
Definition
cell in a solution w/ low solute concentration
cytolysis, burst
Term
hypertonic
Definition
cell in a solution w/high solute concentration.
water flows out of cells, plasmolysis, shrink
Term
isotonic
Definition
cell and solution its in has the same conc.
Term
cytoskeleton made up of
Definition
microtubules- largest
intermediate filaments
microfilaments-smallest
Term
microtubules
Definition
made from tubulin in a 9+2 arrangement, function as railroad for intracellular transport.
found in spindle apparatus of mitosis, flagella, cilia
Term
intermediate filaments
Definition
support and maintain the shape of cell
Term
microfilaments
Definition
made from actin and involved in cellular motility, muscle contraction, cytokinesis
Term
Cell cycle:
Definition
Interphase (longest)
Mitosis
Term
Interphase made up of
Definition
G1, S, G2
Term
Mitosis
Definition
prophase
metaphase
anaphase
telophase
Term
G1, interphase
Definition
protein and nucleic acid synthesis to prepare for rep, production of organelles
Term
S
Definition
DNA replication
Term
G2
Definition
continued growth in preparation of mitosis
Term
Prophase
Definition
chromosomes condense
nuclear envelope disapears
polarization of centrioles
Term
Metaphase
Definition
chromosomes line up on metaphase plate
spindle fibers attach at centromes
Term
anaphase
Definition
spindle fibers pull sister chromatids apart towrd the centrioles
cleavage furrows begins forming
Term
telophase
Definition
nuclear membranes reform
compleation of cytokinesis
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