Term
True or False
The dominant white (I) allele inhibits pigmentation |
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Definition
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Term
| What is the midparent value? |
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Definition
| The 'halfway point' between the expression of parental genes. |
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Term
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Definition
| Group of genes with loci on the same chromosome |
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Term
| What is the definition of 'linkage'? |
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Definition
| Greater association of 2+ non allelic genes than you would expect to see from independent assortment |
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Term
True or False
Genes on separate chromosomes can be linked |
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Definition
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Term
| If genes are unlinked, what proportion of recombinant offspring vs parental offspring would you expect to see in a test cross? |
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Definition
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Term
| How many different gametes are possible for an individual heterozygous for two unlinked loci? |
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Definition
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Term
| If genes are >50cM apart, will they segregated as if they are linked or unlinked? |
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Definition
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Term
| What is a molecular marker? |
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Definition
| detectable DNA difference between chromosomes at specific locations |
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Term
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Definition
| single nucleotide polymorphism |
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Term
| If an SNP occurs in a coding region, but the encoded amino acid is not changed, is the polymorphism synonymous or non-synonymous? |
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Definition
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Term
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Definition
| Insertion/deletion of a short DNA sequence |
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Term
| What are retrotransposons? |
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Definition
| expanding sequence of DNA |
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Term
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Definition
| repeats of 2 nucleotides, e.g. ATATATAT, usually found only in coding regions of DNA (genes) |
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Term
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Definition
| generates 10000's of copies of a piece of DNA |
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Term
| What do oligonucleotides do in PCR? |
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Definition
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Term
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Definition
| starting point for DNA synthesis |
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Term
| What is chromosome mapping? |
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Definition
| Determining which segments of DNA come from which ancestor |
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Term
| What are candidate genes? |
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Definition
| Genes that are likely responsible for a phenotypic trait (suspects!) |
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Term
True or False
Highly conserved amino acid positions are likely funcitonally important |
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Definition
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