Term
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Definition
| The epigenome, paramutation, in maize |
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Term
| What is the phenotype of a mouse with a heavily methylated A^vy allele? |
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Definition
pseudo-agouti
(partially methylated = mottled) |
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Term
| What is the phenotype of a mouse with an unmethylated A^vy allele? |
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Definition
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Term
| In an A^vy a X aa cross, if the male parent has the ^vy gene, what will the offspring proportions be? |
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Definition
| 40% yellow 40% mottled 20% pseudoagouto |
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Term
In an A^vy a X aa cross in mice , if the female parent has the ^vy gene, what will the offspring proportions be?
a/a is an agouti mouse
A^vy/a is a yellow mouse with mottling |
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Definition
| Offspring proportions depend on the mom's phenotype. If mom is yellow, there are more yellow offspring If mom is mottled, there are more mottled offspring If mom is pseudo-agouti, there are more pseudoagouti than the previous two examples, but the yellow & mottled are still larger proportions |
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Term
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Definition
| The effect that diet has on mendelian inheritance |
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Term
| If mom is fed folgate (a methyl donor) will there be more yellow or mottled/pseudoagouti offspring? Will this shift in distribution persist in the F2? |
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Definition
| Mottled & pseudoagouti percentages will be higher Yes, the F2 will also have more mottled & pseudoagouti offspring |
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Term
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Definition
| The interaction of specific alleles of a gene(in a heterozygous individual) that results in a heritable change in expression of one of the alleles. *they act in TRANS |
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Term
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Definition
| dark staining regions of a chromosome |
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Term
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Definition
| light staining regions of a chromosome |
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Term
| What are the two types of chromatin as described by brinks? |
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Definition
Orthochromatin (concerned w/ genome)
Parachromatin (concerned w/ epigenome) |
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Term
| _______ is responsible for changes in the genome in response to the cellular environment. |
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Definition
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Term
| What is the 'R' gene in maize? |
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Definition
| Codes for a transcription factor which turns on the anthocyanin pathway in aleurone tissues (relates to the colouring of the kernels) |
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Term
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Definition
| Portion of the genome that gives rise to heritable genetic variations that are not predictable using Mendelian laws |
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Term
| What is microgametogenesis? |
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Definition
| The process for producing pollen grain gametes (microspores) |
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Term
| Active genes are (under / over) methylated |
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Definition
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Term
| What mediates the methylation of DNA? |
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Definition
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Term
| As the degree of methylation _______, the degree of gene expression ________. |
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Definition
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Term
True or False
Methylation patterns are not heritable |
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Definition
False
once established, methylation patterns are heritable for future cells |
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Term
| Where does methylation occur? |
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Definition
on position 5 of the cytosine of C-G doublets in DNA (5-methylcytosine)
-at CpG sites of DNA |
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