Term
| Selective Serotonin Reuptake Inhibitors (SSRIs)examples |
|
Definition
Citalopram (Celexa)
Escitalopram (Lexapro)
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Paroxetine (Paxil)
Sertraline (Zoloft) |
|
|
Term
| irst line of treatment for major depression? |
|
Definition
| Selective Serotonin Reuptake Inhibitors (SSRIs) |
|
|
Term
| Selective Serotonin Reuptake Inhibitors (SSRIs) side effects |
|
Definition
| Agitation, insomnia, headache, nausea and vomiting, sexual dysfunction, and hyponatremia |
|
|
Term
| Selective Serotonin Reuptake Inhibitors (SSRIs) contraindications ? |
|
Definition
| Contraindicated in people taking MAOIs |
|
|
Term
| "Herbal" SSRI like medication taken by many? |
|
Definition
|
|
Term
| Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)examples |
|
Definition
Venlafaxine (Effexor)
Duloxetine (Cymbalta) |
|
|
Term
| Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)side effects |
|
Definition
| Hypertension (venlafaxine), nausea, insomnia, dry mouth, sweating, agitation, headache, sexual dysfunction |
|
|
Term
| Serotonin Norepinephrine Reuptake Inhibitors (SNRIs) contraindications |
|
Definition
| Contraindicated in people taking MAOIs |
|
|
Term
| what is cymbalta's advantage over effexor? |
|
Definition
| Cymbalta has the advantage of decreasing neuropathic pain |
|
|
Term
| which SNRI is usually tried after SSRI's failed? |
|
Definition
|
|
Term
| Norepinephrine Reuptake Inhibitors (NRIs)example? |
|
Definition
|
|
Term
| Norepinephrine Reuptake Inhibitors (NRIs)side effects? |
|
Definition
| Insomnia, sweating, dizziness, dry mouth, constipation, urinary hesitancy, tachycardia, decreased libido |
|
|
Term
| Norepinephrine Reuptake Inhibitors (NRIs) contraindications? |
|
Definition
| Contraindicated in people taking MAOIs |
|
|
Term
| Norepinephrine Reuptake Inhibitors (NRIs) main use? |
|
Definition
Antidepressant effects similar to SSRIs and TCAs
Useful with severe depression and impaired social functioning |
|
|
Term
| Serotonin Receptor Antagonists/Agonists (SRA) example |
|
Definition
| Nefazodone (formerly sold as Serzone) |
|
|
Term
| Serotonin Receptor Antagonists/Agonists (SRA)side effects |
|
Definition
| Sedation, hepatotoxicity, dizziness, hypotension, paresthesias |
|
|
Term
| Serotonin Receptor Antagonists/Agonists (SRA)contraindications |
|
Definition
| Contraindicated in people taking MAOIs |
|
|
Term
| Serotonin Receptor Antagonists/Agonists (SRA)benefits over an SSRI |
|
Definition
Lower risk of long-term weight gain than SSRIs or TCAs
Lower risk of sexual side effects than SSRIs |
|
|
Term
| Norepinephrine Dopamine Reuptake Inhibitor (NDRI)example |
|
Definition
|
|
Term
| Norepinephrine Dopamine Reuptake Inhibitor (NDRI)side effects |
|
Definition
| Agitation, insomnia, headache, nausea and vomiting, seizures (0.4%) |
|
|
Term
| Norepinephrine Dopamine Reuptake Inhibitor (NDRI)contraindications |
|
Definition
Contraindicated in people taking MAOIs
High doses increase seizure risk, especially in people who are predisposed to them |
|
|
Term
| Norepinephrine Dopamine Reuptake Inhibitor (NDRI)benefits? |
|
Definition
Stimulant action may reduce appetite
May increase sexual desire
Used as an aid to quit smoking |
|
|
Term
| Serotonin Norepinephrine Disinhibitors (SNDIs)example |
|
Definition
|
|
Term
| Serotonin Norepinephrine Disinhibitors (SNDIs)uses |
|
Definition
| Antidepressant effects equal SSRIs and may occur faster |
|
|
Term
| Serotonin Norepinephrine Disinhibitors (SNDIs)side effects |
|
Definition
| Weight gain, sedation, dizziness, headache; sexual dysfunction is rare |
|
|
Term
| Serotonin Norepinephrine Disinhibitors (SNDIs)warnings and contraindications |
|
Definition
Drug-induced somnolence exaggerated by alcohol, benzodiazepines, and other CNS depressants
Contraindicated in people taking MAOIs |
|
|
Term
| Tricyclic Antidepressants (TCAs)examples |
|
Definition
Amitriptyline (Elavil)
Clomipramine (Anafranil)
Desipramine (Norpramin)
Doxepin (Adapin, Sinequan)
Imipramine (Tofranil)
Nortriptyline (Aventyl, Pamelor)
Protriptyline (Vivactil) |
|
|
Term
| Tricyclic Antidepressants (TCAs)uses |
|
Definition
Therapeutic effects similar to SSRIs, but side effects are more prominent
May work better in melancholic depression TCAs can worsen many cardiac and medical conditions |
|
|
Term
| Tricyclic Antidepressants (TCAs)side effects |
|
Definition
| Dry mouth, constipation, urinary retention, blurred vision, orthostatic hypotension, cardiac toxicity, sedation |
|
|
Term
| Tricyclic Antidepressants (TCAs)cautions and contraindications |
|
Definition
Lethal in overdose
Use cautiously in older adults and those with cardiac disorders, elevated intraocular pressure, urinary retention, hyperthyroidism, seizure disorders, and liver or kidney dysfunction.
Contraindicated in people taking MAOIs |
|
|
Term
| Tricyclic Antidepressants (TCAs)are normally taken after which group of drugs fails? |
|
Definition
|
|
Term
| Monoamine Oxidase Inhibitors (MAOIs)examples |
|
Definition
Phenelzine (Nardil)
Selegiline Transdermal System Patch (EMSAM)
Tranylcypromine (Parnate) |
|
|
Term
| Monoamine Oxidase Inhibitors (MAOIs)uses |
|
Definition
| Efficacy similar to other antidepressants, but dietary restrictions and potential drug interactions make this drug less desirable |
|
|
Term
| Monoamine Oxidase Inhibitors (MAOIs)side effects |
|
Definition
Insomnia, nausea, agitation, and confusion
Potential for hypertensive crises or serotonin syndrome with concurrent use of other antidepressants |
|
|
Term
| Monoamine Oxidase Inhibitors (MAOIs)warnings and contraindications |
|
Definition
Contraindicated in people taking other antidepressants
Tyramine-rich food could bring about a hypertensive crisis
Many other drug interactions |
|
|
Term
| serotonin syndrome symptoms |
|
Definition
• Hyperactivity or restlessness
• Tachycardia → cardiovascular shock
• Fever → hyperpyrexia
• Elevated blood pressure
• Altered mental states (delirium)
• Irrationality, mood swings, hostility
• Seizures → status epilepticus
• Myoclonus, incoordination, tonic rigidity
• Abdominal pain, diarrhea, bloating
• Apnea → death |
|
|
