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Final Exam - Lymphedema
Lymphedema lecture & lab
116
Health Care
Graduate
04/28/2013

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Term
Main organs of lymphatic system
Definition
lymph nodes
lymph vessels

(thymus glands, spleen, tonsils, peyer's patches)
Term
Function of lymphatic system
Definition
fluid regulation
immunological
Term
Chyle =
Definition
milky white lymph fluid (esp p fatty meal)
fatty acid absorption from intestines
Term
Lymph system: intrinsic or extrinsic pump?
Definition
intrinsic pump
Term
Types of lymph vessels (in increasing order of size)
Definition
capillary
pre-collector
collector
trunks & ducts
Term
Location of "swinging flaps" in lymph system
Definition
capillaries
Term
Capillaries: one-way valves
Definition
none
Term
Functions of pre-collector lymph vessels
Definition
absorption
transport
(has some smooth mm & valves)
Term
Function of collector lymph vessels
Definition
transportation (no absorption)
Term
function unit of lymphatic system
Definition
lymphangion
Term
lymphangion =
Definition
section of collector btwn distal valve & proximal valve (in collector)
Term
Types of collectors
Definition
superficial
deep
perforating
Term
Lymphatic ducts empty into...
Definition
vv circulation
Term
Largest lymph vessel =
Definition
thoracic duct
Term
Location of thoracic duct
Definition
parallel to spine, L2 to left venous angle
Term
Quadrant drained by thoracic duct
Definition
L upper
bilat lower
Term
Cisterna chyle =
Definition
abdominal portion of thoracic duct
sac-like enlargement
Term
Quadrant drained by R lymphatic duct
Definition
R upper
Term
venous angle =
Definition
jxn btwn

internal jugular v
& subclavian v
Term
BP lowest where?
Definition
at left venous angle
Term
Lymph node fxn
Definition
filter bacteria, toxins, dead cells
produce lymphocytes
regulate protein concentration
Term
Avg # of lymph nodes in body
Definition
600-700
Term
Swollen lymph node signifies...
Definition
body is working hard to filter lymph (esp in illness)
Term
Lymph node distributions are usually...
Definition
medial
Term
Path of lymph flow
Definition
interstitial fluid
capillaries
pre-collectors
collectors
nodes
collectors
trunks/ducts
venous angle
vascular circulation
Term
Watersheds (5)
Definition
median-sagittal
transverse
clavicle
spine of scapulae
chaps (gluteal)
Term
one way
(lymph flow OR blood flow?)
Definition
lymph flow
Term
circular flow
(lymph flow OR blood flow?)
Definition
blood flow
Term
1-2 L/day
(lymph flow OR blood flow?)
Definition
lymph
Term
L/min
(lymph flow OR blood flow?)
Definition
blood
Term
intrinsic vessel contraction
(lymph flow OR blood flow?)
Definition
lymph
Term
central pump
(lymph flow OR blood flow?)
Definition
blood
Term
peripheral pressure unaffected by limb dependency
(lymph flow OR blood flow?)
Definition
lymph
Term
limb dependency incr peripheral pressure
(lymph flow OR blood flow?)
Definition
blood
Term
obstruction >> high protein fluid accumulation
(lymph flow OR blood flow?)
Definition
lymph
Term
obstruction >> low protein fluid accumulation
(lymph flow OR blood flow?)
Definition
blood
Term
long latency period btwn injury & clinical appearance
(lymph flow OR blood flow?)
Definition
lymph
Term
short latency period btwn injury & clinical appearance
(lymph flow OR blood flow?)
Definition
blood
Term
fluid filtered by nodes
(lymph flow OR blood flow?)
Definition
lymph
Term
fluid filtered by kidneys
(lymph flow OR blood flow?)
Definition
blood
Term
Diffusion is dependent on... (4)
Definition
molecule size
concentration
distance
temperature
Term
Starling's Law
Definition
avg blood capillary pressure = avg colloid osmotic pressure
Term
blood capillary pressure > colloid osmotic pressure
Definition
ultrafiltration
Term
blood capillary pressure < colloid osmotic pressure
Definition
reabsorption
Term
Types of hyperemia
Definition
active (hand in hot water)
passive (DVT)
Term
Lymph load =
Definition
amt of substances that have to be removed from interstitium by lymphatic system
(net ultrafiltrate)
Term
Average lymph load
Definition
75-100 g/day
Term
LTV (lymph time volume)
Definition
SPEED of lymph transport
Term
TC (transport capacity)
Definition
amt of lymph transported (similar to HRmax)
Term
Functional Reserve
Definition
amt of transport capacity not being utilized
Term
Types of lymphatic system insufficiency (3)
Definition
high volume (dynamic)
low volume (mechanical)
safety valve
Term
High volume insufficiency
Definition
TC exceeded by lymph load
(healthy lymphatic system, but overloaded)
Term
Low volume insufficiency
Definition
TC drops below lymph load
(body can't handle even normal lymph load)
Term
Reasons for mechanical insufficiency - mechanical
Definition
valve insufficiency
vessel wall insufficiency
lymphangiospasm
lymphangioparalysis
Term
Reasons for mechanical insufficiency - organic
Definition
filiariasis (parasite)
RA
vv disease of LE
trauma
XRT
surgery
Term
Safety valve insufficiency
Definition
combo of high volume & low volume insufficiency (decr TC, incr LL)
Term
Lymphedema def'n
Definition
"abnormal accumulation of a protein-rich fluid in the interstitium, which causes chronic inflammation and reactive fibrosis of the affected tissue"
Term
Classifications of lymphedema
Definition
primary (due to dysplasia)
secondary (due to sx, radiation, infection, trauma, etc)
Term
Types of primary lymphedema
Definition
hypoplasia
hyperplasia
aplasia
inguinal node fibrosis
Term
common site of hypoplasia
Definition
primary LE
Term
which is more common:
hypoplasia or hyperplasia?
Definition
hypoplasia
Term
Hypoplasia =
Definition
fewer than normal lymph collectors, insufficient diameter/caliber
Term
Hyperplasia =
Definition
lymph vessels dilated >> insufficient valves
Term
Milroy's Disease =
Definition
Type I congenital hereditary lymphedema
Term
Type I congenital hereditary lymphedema:
M v F
Definition
more common in males
Term
Meige's Syndrome =
Definition
Type I non-congenital hereditary lymphedema
Term
Type I non-congenital hereditary lymphedema:
M v F
Definition
more common in females
Term
Meige's Syndrome: co-anomalies
Definition
syndactylism (fused toes)
distichiasis (double eyelashes)
myopia (near-sightedness)
yellow nails
vertebral anomalies
cleft palate
port wine stains
Term
Praecox lymphedema
Definition
occurs before 35yo
Term
Tarda lymphedema
Definition
occurs after 35yo
Term
Primary cause of secondary lymphedema
Definition
filariasis

(CA Rx in non-tropical regions)
Term
Other causes of secondary lymphedema
Definition
trauma to nodes/vessels
infections (cellulitis)
sx
malignant tumors
obesity
dependency
CVI (chronic vv insufficiency?)
lymphadenectomy
radiation
Term
Cause of lymphatic cysts, papillomas, fistulas, blisters, etc.
Definition
lymphedema with reflux (incompetent valves)
Term
Stages of lymphedema
Definition
Latency
Stage I (spontaneous reversible)
Stage II (spontaneously irreversible)
Stage III (lymphostatic elephantiasis)
Term
Stages of lymphedema - latency
Definition
decr TC
no visible edema
subjective complaints (paresthesia)
Term
Stages of lymphedema - Stage I
Definition
accumulation of hi-protein fluid
pitting edema
reduces c elevation (no fibrosis)

lasts 1-2 wks, then resolves (but underlying cause still remains)
Term
Stages of lymphedema - Stage II
Definition
accumulation of hi-protein fluid
progressively more difficule pitting
no change c elevation
CT proliferation (fibrosis)
Term
Stages of lymphedema - Stage III
Definition
accumulation of hi-protein fluid
non-pitting
fibrosis/sclerosis (severe induration)
skin changes (papillomas, hyperkeratosis, wounds, etc)
Term
Angiosarcoma =
Definition
reddish-blue/blackish-blue lumps that rapidly incr in size, bleed easily, ulcerate
very rare
poor Px (>>CA)
can develop p long-standing lymphedema
Term
Subjective info from lymphedema pt - current
Definition
time of onset (slow v fast)
characteristics of onset (dist to prox, areas of involvement)
pain (discomfort)
provoking factors
Term
Subjective info from lymphedema pat - past
Definition
hx of swelling
family hx
infection hx
co-morbidities
wounds
Term
Grading pitting edema: 1+
Definition
edema barely detectable
Term
Grading pitting edema: 2+
Definition
slight indentation when skin depressed
Term
Grading pitting edema: 3+
Definition
deeper finger indentation, returns to normal 5-30 sec
Term
Grading pitting edema: 4+
Definition
extremity 1.5x larger than normal
Term
Components of objective observation for lymphedema pts
Definition
skin folds
skin changes
skin integrity
blisters/cysts
skin color
hair distribution (affected by aa/vv ∆s)
scars
Term
Methods of objective msmt in lymphedema pts
Definition
limb volume
perometry (IR light)
bioelectrical impedance spectroscopy
photographs
Term
Lymphedema def'n in literature
Definition
5-10% incr in volume
Term
DASH questionnaire (fxnl abilities)
Definition
dress self
above-head (reaching height)
shoes, socks
hygiene
Term
Dx tests for lymphedema
Definition
direct lymphography
indirect lymphography
fluorescence microlymphography
lymphoscintigraphy
vv doppler (r/o blood clot)
CT (r/o CA)
MRI
Term
Diff Dx for lymphedema
Definition
lipedema
vv edema
cardiac edema
DVT
CHF
malignant lymphedema
cirrhosis of liver
Term
Lipedema
Definition
genetic predisposition to high fatty distrib
pear-shaped
mostly women
bilaterally, symmetrical
(-) Stemmer's sign
no pitting
no cellulitis
painful, tender, easy bruising
Term
Vv edema
Definition
gaiter distrib
hemosiderin staining
weeping
atrophic skin
subq fibrosis
Term
Dx of acute DVT
Definition
vv doppler/duplex ultrasound
Term
Cardiac edema
Definition
greatest distally
bilateral
significant pitting
ø pain
reduces c elevation
Term
CHF
Definition
significant pitting
orthopnea, DOW, paroxysmal nocturnal dyspnea
jugular v distention
Term
malignant lymphedema
Definition
pain, paresthesia
edema = central location
rapid development
ulcers
prox to dist
Term
Methods of Rx for lymphedema
Definition
complete decongestive therapy
pneumatic compression
sx
elastic garments
meds
Term
Types of complete decongestive therapy
Definition
manual lymph drainage
compression bandaging
remedial exercise
meticulous skin/nail care
self-care ed
Term
Phases of therapy for lymphedema
Definition
Phase I - Treatment Phase
Phase II - Maintenance Phase
Term
Reasons for failure of complete decongestive therapy
Definition
malignant lymphedema
insufficient treatment (MLD only, improper bandaging)
lack of compliance
improper dx
Term
pneumatic compression = ________ treatment
Definition
adjunctive
Term
pneumatic compression: affect on protein
Definition
none (no skin stretch mechanism)
Term
flat knit elastic garment used for
Definition
compression
Term
circular knit elastic garment used for
Definition
vascular issues
Term
Basic principles of MLD: stroke intensity
Definition
gentle pressure
Term
Basic principles of MLD: stroke sequence
Definition
working phase to resting phase
Term
Basic principles of MLD: stroke duration
Definition
≥1 sec working phase
5-7x in each area
Term
Basic principles of MLD: stroke direction
Definition
depends on lymph flow
Term
Rule of Rx (MLD) (3)
Definition
area closest to vv angle
regional lymph nodes
extremity - prox to distal
Term
Vodder MLD strokes (4)
Definition
stationary circles (regional nodes, neck, face)
pump (extremities)
scoop (extremities only)
rotary (trunk, large body surfaces)
Term
things to check p applying lymphedema bandaging (3)
Definition
squeeze to check gradient
check finger tips for circulation
check for comfort
Term
Contraindications for lymphedema bandaging
Definition
acute infection (cellulitis)
cardiac edema

arterial disease (relative Øind)
malignant lymphedema (relative Øind)
Term
UE remedial ex (example)
Definition
posture
abdominal breathing
head turns
shoulder circles
isometric chest presses, breast stroke
shoulder press, elbow circles, pot stirring
triceps arm elevated
biceps
FA sup/pron
wrist circles
fist, finger dexterity
Term
LE remedial ex (standing)
Definition
posture
breathing
low back stretch
fwd stance
front stance
bkwd stance
gastroc/soleus stretch
Term
LE remedial ex (sitting)
Definition
posture
breathing
sidebending stretch
knee to chest
marching
leg crossing
add squeezes
knee flex/ext
ankle DF/PF
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