Term
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Definition
| Special lymphatic capillaries in the small intestine-transport lipids from digestive tract |
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Term
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Definition
-have larger diameter
-thinner walls
-overlap allows fluids, solutes, viruses, bacteria to enter preventing return to inter-cellular space |
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Term
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Definition
-skin
-mucus membranes
-serous membranes lining body cavities |
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Term
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Definition
| -larger vessels that accompany deep arteries and veins |
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Term
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Definition
-Everything inferior to diaphragm
-Everything superior to diaphragm and on left side
-Empties into left subclavian vein |
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Term
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Definition
| -contains dividing lymphocytes |
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Term
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Definition
| -aggregated lymphoid nodules clustered deep to small intestinal epithelial lining |
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Term
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Definition
| a shallow indentation where blood vessels and nerves reach the lymph node |
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Term
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Definition
Bundles of capillary fibers
-from capsule into inferior lymph node |
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Term
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Definition
-carry lymph
-from peripheral tissues to lymph node |
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Term
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Definition
-leave lymph node at hilus
-carry lymph to venous circulation |
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Term
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Definition
| -contains macrophages and dendritic cells |
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Term
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Definition
| -contains B cells within germinal centers |
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Term
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Definition
| -dominated by T cells entering via blood vessels |
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Term
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Definition
-contains B cells and plasma cells
-has no blood-thymus barrier |
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Term
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Definition
| -organized lines of B cells and plasma proteins |
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Term
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Definition
-in mediastinum
-deteriorates after puberty |
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Term
| Reticular epithelial cells (REC's) |
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Definition
-surround lymphocytes in the cortex
-maintain blood-thymus barrier
-secrete thymic hormones (thymosins) |
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Term
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Definition
-stimulate stem cell divisions
-T cell differentiation |
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Term
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Definition
-divide in the cortex
-T cells migrate to medulla
-Mature T cells leave thymus by medullary blood vessels |
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Term
| 3 functions of the spleen |
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Definition
1. removal of abnormal blood cells and other blood.
2. storage of iron recycled from RBCs.
3. Initiation of immune responses by T and B cells
- in response to antigens in circulating blood. |
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Term
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Definition
-always act first
-always act the same way
-against any type of invading agent
-operates with specific defenses to provide resistance |
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Term
| 7 Types of Nonspecific Resistance |
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Definition
1. physical barriers
2. phagocytic cells
3. immunologival surveillance
4. interferons
5. complement
6. inflammation
7. fever |
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Term
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Definition
-1st line of cellular defense
-attack and remove dangerous microorganisms before lymphocytes are activated |
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Term
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Definition
-neutrophils: first at injury site, fast
-eosinophils:slower
-Leave bloodstream and enter peripheral tissues |
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Term
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Definition
-phagocytic cells derived from monocytes
-Once activated either engulf pathogen and destroy; bind to so other cells can destroy; release lymphotoxin and destroy |
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Term
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Definition
-respond to specific antigens
-with coordinated action of T and B cells |
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Term
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Definition
-provide cell-mediated immunity
-defend against abnormal cells and pathogens inside CELLS |
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Term
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Definition
-provide antibody-mediated immunity
-defend against antigens and pathogens in BODY FLUIDS
-attack antigens by producing specific antibodies |
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Term
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Definition
Innate- present at birth
Acquired- after birth (need exposure to antigen) |
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Term
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Definition
Active- antibodies develop after exposure to antigen and results in immune response
Passive- antibodies are transferred from another source. |
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Term
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Definition
1.Specificity
2.Versatility
3.Memory
4.Tolerance |
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Term
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Definition
-secrete suppression factors
-inhibit responses of T and B cells
-After initial immune response
-Limit immune reaction to single stimulus |
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Term
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Definition
1.stimulate T cell divisions
2.attract and stimulate macrophages
3.attract and stimulate NK cells
4.promote activation of B cells |
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Term
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Definition
| -synthesize and secrete antibodies into interstitial fluid |
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Term
| 7 Functions of Ag-Ab Complexes |
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Definition
1.neutralization of Ag binding sites
2.precipitation and agglutination
3.activation of complement
4.attraction of phagocytes
5.opsonization
6.stimulation of inflammation
7.prevention of bacterial and viral adhesion |
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Term
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Definition
| -increases phagocyte efficiency |
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Term
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Definition
*First time you fight the infection*
-produces initial response
-takes time to develop (2 weeks)
-Ag activate B cells
-Plasma cells differentiate
-Ab titer slowly rises
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Term
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Definition
*Next Exposure*
-triggers secondary response
-more extensive and prolonged
-memory cells already primed
-activates memory B cells
-secretes Ab in massive quantities |
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Term
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Definition
| Inappropriate or excessive immune response to antigens |
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