Term
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Definition
SXS; cough , chest tightness. Symptoms come after a long peroid of exposure.
- 20% have personal or family history of Atopy
-Sxs may persist after perminant removal |
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Term
| Types of Occupational Asthma |
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Definition
Type 1 - humoral mediated IGE (mast cells--> histamine)
Early / immediate responce
Typer 4: Cellular immune responce (esinophils)
Late responce / 3hrs |
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Term
| Occupational Asthma pathway |
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Definition
| Occ risk factor --> Inflamation (smooth muscle hypertrophy)& triggers -> Hyperresponsive Airway --> Airflow limited --> sxs --> remodeling |
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Term
| Occupational Asthma triggers |
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Definition
Animals - lipocalin
flour
Isocynates |
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Term
| Occupational Asthma diagnosis |
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Definition
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Term
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Definition
Due to cotton and coal dust
SXS; cough , DIB, fever
patho: histamines, leukotrienes, exotoxing, fibrosis, reduced pulm function, chronic bronchitis. |
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Term
| Coal workers pneumoconiosis |
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Definition
Caplans syndrome = lung disease + Reheumatoid Arthritis
can also be due to silica |
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Term
| Hypersensitivity Pneumonitis |
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Definition
Organic dust
Restrictive pattern: chronic fibrosis (intersisitial phneumonia)
Immunological responce: type III immune complex responces with presence of IgG precipitants |
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Term
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Definition
| Hypersensitivity Pneuminits from mold of sugar cane. |
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Term
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Definition
Intersitial Lung disease du to chronic exposure to high concentrations of inorganic dust.
non-neoplastic rxn of lungs to inhailed mineral oils or dust
Examples: fiberglass, silica, tin, vermiculi |
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Term
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Definition
Intersitial Lung disease du to chronic exposure to high concentrations of inorganic dust.
non-neoplastic rxn of lungs to inhailed mineral oils or dust
Examples: fiberglass, silica, tin, vermiculi |
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Term
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Definition
DX: PFT's for restrictive pattern
Spirometry for best diagnostic tool |
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Term
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Definition
Lung disease from contaminated mild of animals
SXS: flue like
exposere; vets, slaughterhouse, farmers
Rx; tertracycline, rifampicin, gent |
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Term
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Definition
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Term
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Definition
Mill fever, metal fume fever (zince oxide fever) Polymer fume fever (plastics)
exposure; oxides of heavy metals,
SXS; self limiting , no inflitrates
flue like illness
x-ray clear |
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Term
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Definition
Silica
Arsnic
Asbestose
Hydrocarbons / polyaromatic
uranium mining
Bis-chlormetyl ester
chromiun
beryllium
Nickel
Iron Ore
mustard gass |
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Term
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Definition
Two acceptable expiratory measure with not more than 5% diffrence in FVC obtained from two best curves.
Restrictive = Decreased lung volumes and FVC
Obstructive = decreased flow rates and FEV1 |
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Term
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Definition
RV and FRC go up in old men
RV and FRC lower baseline in women |
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Term
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Definition
VC - amount of air after max exhil = 4.6 L (IVR+VT+EVR)
TV= normal volume air inhailed and exhailed = 500cc
RV= amount of air after max exhail = 1.2 L
TLC= amount of air in lungs after max inhail= 6L
FRC= amount of air in lungs after tital breath out = 2.4 L
ERV= 1.2 L
IRV= 2.3 L |
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Term
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Definition
Looks like Sarcoidosis
simple blood test called BeLPT or the beryllium lymphocyte proliferation test that determines if your immune system is reacting to berylium
No RX |
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Term
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Definition
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