Term
| Which vitamin prevents bone loss and fractures? |
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Definition
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Term
| Decrease in Vitamin D or calcium causes |
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Definition
| Decrease in calcium absorbtion |
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Term
| Decrease in absorbed calcium decreases what? |
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Definition
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Term
| What does decreased serum Ca++ levels cause an increase of? |
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Definition
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Term
| What does parathymoid hormone increase the rate of? |
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Definition
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Term
| What does increased bone remodelling lead to? |
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Definition
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Term
| What is the ultimate effect of increase bone loss |
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Definition
| Greater risk of bone fracture |
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Term
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Definition
1. Calcium metabolism 2. Cell differentiation (particularly of collagen/skin epithelium) 3. Immunity |
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Term
| Vitamin D and calcium metabolism |
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Definition
| Vitamin D enhances calcium absorbtion in the gut and renal tubules |
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Term
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Definition
| important for cell mediated immunity and coordination of immune response |
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Term
| What can lead to a decrease in bone mass/quality? (2) |
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Definition
1. Early menopausal bone loss 2. Calcium/Vit D deficiency |
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Term
| What does a decrease in bone mass/quality lead to eventually? |
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Definition
| Low bone mass/impaired bone quality |
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Term
| What can also influence a low bone mass/impaired bone quality? |
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Definition
| Inadequate peak bone mass |
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Term
| With the addition of trauma, what will low bone mass/impaired quality lead to? |
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Definition
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Term
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Definition
| The amount of bony tissue present at the end of skeletal maturation |
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Term
| What can concentrate mechanical stress in bones? |
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Definition
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Term
| What is the relationship of bone fracture occurance and resorbtion cavities? |
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Definition
| Bone most likely to fracture at the site of bone resorbtion |
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Term
| Causes of inadequate peak bone mass? |
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Definition
1. Genetic factors 2. Inadequate nutrition during growth & development 3. Limited physical activity 4. Diseases/drugs during growth that impair bone aquisition |
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Term
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Definition
| light porous bone enclosing large spaces which gives a spongy appearance |
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Term
| Post menopausal women and cancellous bone |
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Definition
| High rate of cancellous bone loss |
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Term
| What can lead to decreased vitamin d synthesis in the aged? (2) |
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Definition
1. Impaired renal function 2. Decreased sunlight exposure |
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Term
| What does decreased vitamin D synthesis lead to? |
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Definition
| Decreased calcium absorbtion |
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Term
| What condition is caused by decreased calcium absorbtion? |
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Definition
| Secondary hyperparathymoidism |
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Term
| What also causes decreased calcium absorbtion in the aged? (2) |
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Definition
1. Oestrogen deficiency 2. Low dietary calcium intake |
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Term
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Definition
1. Muscle weakness 2. Poor balance 3. Poor eyesight 4. Benzodiazepine use |
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Term
| Risk for fractures in a fall (4) |
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Definition
1. Failure to break a fall 2. Falling to the side 3. Age 4. Low bone mass |
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