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LUDI Catabolism of Glucose
Glycolysis and TCA cycle
24
Dentistry
Undergraduate 2
04/23/2014

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Term
Three possible fates of pyruvate
Definition
CO2 + H20 (aerobic respiration)
Lactate (anaerobic respiration)
Ethanol (fermentation)
Term
Glucose ->
Definition
Glucose 6-Phosphate
Hexokinase
ATP -> ADP
Term
Glucose 6-Phosphate ->
Definition
Fructose 6-Phosphate
Phosphoglucose isomerase
Term
Fructose 6-Phosphate ->
Definition
Fructose 1,6-Bisphosphate
Phosphofructo kinase
ATP -> ADP
Term
Fructose 1,6-Bisphosphate ->
Definition
Dihydroxyaceton phoshate + Glyceraldehyde 3-Phosphate
Aldolase
Term
Dihydroxyacetone phosphate ->
Definition
Glyceraldehyde 3-Phosphate
Triose phosphate isomerase
Term
Glyceraldehyde 3-Phosphate ->
Definition
1,3-Bisphosphoglycerate
+ Pi
NAD+ -> NADH
Term
1,3-Bisphosphoglycerate ->
Definition
3-Phosphoglycerate
Phosphoglycerate kinase
ADP-ATP
Term
3-Phosphoglycerate ->
Definition
2-Phosphoglycerate
Phosphoglycerate mutase
Term
2-Phosphoglycerate ->
Definition
Phosphoenol pyruvate
Enolase
-H2O
Term
Phosphoenol pyruvate ->
Definition
Pyruvate
Pyruvate kinase
ADP -> ATP
Term
Pyruvate dehydrogenase reaction
Definition
Pyruvate
-CO2
-2H
+CoA
makes Acetyl CoA
Term
Fate of 2H produced in pyruvate dehydrogenase reaction
Definition
NAD+ -> NADH + H+
Term
Acetyl CoA + H20 + Oxloacetate ->
Definition
Citrate
Citrate synthase
Term
Citrate (6) ->
Definition
Isocitrate (6)
Aconitase
Term
Isocitrate (6) ->
Definition
Alpha-ketoglutarate (5)
Isocitrate dehydrogenase
-CO2
NAD+ -> NADH
Term
Alpha-ketoglutarate (5) ->
Definition
Succinyl CoA (4)
Alpha-ketoglutarate dehydrogenase
+CoA -CO2
NAD+ -> NADH
Term
Succiny CoA (4) ->
Definition
Succinate (4)
Succiny CoA synthetase
+Pi -CoA
GDP -> GTP
Term
Succinate (4) ->
Definition
Fumarate (4)
Succinate dehydrogenase
FAD -> FADH2
Term
Fumarate (4) ->
Definition
Malate (4)
Fumarase
+H2O
Term
Malate (4) ->
Definition
Oxaloacetate (4)
Malate dehydrogenase
NAD+ -> NADH
Term
Location of glycolysis
Definition
Cytosol
Term
Location of TCA cycle
Definition
Mitochondrial matrix
Term
Location of pyruvate dehydrogenase reaction
Definition
Mitochondrial matrix
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