Term
| Motor aphasia with good comprehension? |
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Definition
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Term
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Definition
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Term
| Sensory aphasia with poor comprehenion? |
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Definition
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Term
| Where is Wernicke's area? |
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Definition
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Term
| A lesion in what area causes conduction aphasia with poor repetition, good comprehension and fluent speech? |
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Definition
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Term
| What is Kluver-Bucy syndrome? |
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Definition
| hyperorality, hypersexuality and disinhibited behavior |
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Term
| Where is the lesion that causes Kluver-Bucy? |
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Definition
| bilateral amygdala lesion |
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Term
| What lesion causes personality changes and deficits in concentration, orientation and judgement with emergence of primitive relflexes? |
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Definition
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Term
| What does a lesion of the right parietal lobe cause? |
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Definition
| hemi-spacial neglect syndrome |
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Term
| What does a lesion of the reticular activating system cause? |
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Definition
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Term
| What does a lesion of the mammilary bodies cause? |
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Definition
| wernicke-korsakoff syndrome |
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Term
| what type of lesion would a patient with a resting tremor, chorea, and athetosis have? |
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Definition
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Term
| What type of lesion causes an intention tremor and limb ataxia? |
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Definition
| cerebellar hemisphere lesion |
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Term
| What type of lesion causes truncal ataxia and dysarthria (speech problems)? |
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Definition
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Term
| What does a lesion of the subthalamic nucleus cause? |
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Definition
| contralateral hemiballismus |
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Term
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Definition
| slow, writing, movements esp of fingers characteristic of basal ganglia lesion |
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Term
| What is hemiballismus and where is the lesion? |
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Definition
suddent wild flailing of an extremity
contralateral subthalamic nucleus
loss of inhibition of thalamus through globus pallidus |
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Term
| What part of the brain does alzheimer's affect? |
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Definition
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Term
| What are the characteristic histological findings in AD? |
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Definition
| senile plaques composed of B amyloid (extracellular) and neurofibrillary tangles (intracellular) made of abnl phosphorylated tau proteins. |
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Term
| What chromosomes/genes is AD associated with in 10% of ppl with AD |
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Definition
| chrom 1, 14, 19 (APOE4 allele) and chrom 21 (p-App gene) |
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Term
| What are the characterisic findings in pick's dz? |
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Definition
| dementia, aphasia, and parkinsonian sx with Pick bodies (intercellular aggregated tau protein. |
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Term
| Where is the cerebral damage in Pick's disease? |
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Definition
| Temporal and frontal lobes |
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Term
| Where is the lesion in HD? |
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Definition
| Basal ganglia--atrophy of the caudate nucleus |
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Term
| What is the mode of inheritance for HD? |
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Definition
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Term
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Definition
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Term
| What chromosome is implicated in HD and what is the repeat? |
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Definition
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Term
| What neurons are lost in HD? |
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Definition
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Term
| What histo characteristics are associated with PD? |
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Definition
| lewy bodies and depigmentation of the substantia nigra |
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Term
| What neurons are lost in PD? |
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Definition
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Term
| What are the 4 main sx associated with PD? |
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Definition
| cogwheel rigidity, resting tremor, postural instability, and akinesia |
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Term
| What toxic exposure is assoc with PD? |
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Definition
| MPTP, a contaminant in street drugs |
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Term
| What Lou Gehrig's Disease? |
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Definition
| ALS amyotrophic lateral sclerosis |
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Term
| What is Werdnig-Hoffmann dz? |
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Definition
| AR inheritance, presents with floppy baby and tongue fasiculations and anterior horn degeneration and death at about age 7. |
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Term
| What part of the brain does polio affect? |
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Definition
| motor neurons-anterior horn |
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Term
| what type of signs (UMN vs LMN) does polio give? |
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Definition
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