Term
| What is Metamucil (Psyllium) classified as and what is it used for? |
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Definition
| It is classified as a bulk forming agent and a laxative and is used for the mgmt of chronic constipation (usually d/t low fiber diet), mgmt of chronic watery diarrhea, and mgmt of pt's who can't strain (d/t surgery, MI, etc). |
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Term
| What is the method of action for metamucil? How long does it take to work? |
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Definition
| It combines with water in the GI tract, forming an emolient gel. The gel promotes peristalsis. It takes about 12-24h to have an effect and 1-3d to reach a plateau. |
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Term
| What conditions prohibit the use of Metamucil? |
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Definition
Undiagnosed abdominal pain
Obstruction
Impaction
N&V
Hypersensitivity to Psyllium
Dysphagia |
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Term
| What are the common side effects of Metamucil? |
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Definition
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Term
| What are the drug-drug interactions associated with Metamucil? |
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Definition
| Decreased absorption of warfarin, salicylates, digoxin, antibiotics, and nitrofurantoin (an antibiotic for UTI's). |
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Term
| How is Bisacodyl (Dulcolax) classified and what is it used for? |
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Definition
| It is a stimulant laxative and is used for the treatment of constipation, as part of the pre-op bowel prep, and as part of the spinal cord injury bowel regimen. |
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Term
| What is the method of action for bisacodyl? How long does it take to work? |
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Definition
| It alters fluid and electrolytes so that fluid accumulation in the colon is increased. It takes 6-12 hrs to have an effect when taken PO and 15-60m. |
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Term
| What conditions prohibit the use of bisacodyl? |
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Definition
Hypersensitivity to bisacodyl
Abdominal Pain
Obstruction
N&V |
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Term
| What situations demand extra caution when adminstering bisacodyl? |
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Definition
Severe CVD
Anal and rectal fissures
Prolonged Use |
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Term
| What are the common side effects of bisacodyl? |
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Definition
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Term
| What are the drug-drug interactions associated with bisacodyl? |
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Definition
Antacids, h2 antagonists, and PPI's can remove enteric coating and thus cause GI upset.
This drug decreases the absorption of other PO meds due to increased motility and decreased transit time. |
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Term
| What is docusate (Colace) classified as and what is it used for? |
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Definition
| A stool softener and a laxative. As a PO Med, it is used for prevention of constipation and straining. Rectally, it is used to soften fecal impactions. |
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Term
| What is the method of action for docusate and how long does it take to work? |
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Definition
| It draws water into the stool resulting in softer feces. It also increases electrolyte and water secretion into the colon. It takes 24-48h to work PO and 2-15min rectally. |
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Term
| In what situations would the use of docusate be prohibited? |
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Definition
Hypersensitivity to docusate
Abdominal pain
N&V |
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Term
| What situations demand extra caution when administering docusate? |
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Definition
Prolonged Use
When prompt results needed |
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Term
| What are the common side effects of docusate? |
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Definition
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Term
| What drug-drug interactions are associated with docusate? |
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Definition
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