Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Lorazepam Mechanism of Action |
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Definition
| Binds to benzodiazepine receptors and enhances the effects of the inhibitory neurotransmitter GABA, causing anticonvulsant, anti-anxiety and amnesic effects |
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Term
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Definition
| Major motor seizures, skeletal muscle relaxant, status epilepticus, premedication prior to cardioversion, preprocedure sedation, acute anxiety stress, violence and/or agitation |
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Term
| Lorazepam Contraindications |
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Definition
| COPD, CNS depression, hypotension, shock, coma, acute closed-angle glaucoma |
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Term
| Lorazepam Adverse Reactions |
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Definition
| Hypotension, drowsiness, amnesia, respiratory depression, blurred vision, nausea, vomiting, syncope, paradoxical CNS stimulation |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| 1-4 mg IV/IO over 2-5 min. Can be repeated in 10-15 min to a max dose of 8 mg per 12 hours |
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Term
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Definition
| 0.05-0.2 mg/kg slow IV/IO/IM over 2 min. May repeat once in 5 min, |
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