Term
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Definition
| Cocaine, procaine, tetracaine |
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Term
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Definition
| lidocaine, bupivacaine, mepivacaine |
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Term
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Definition
| blocks inner portion of Na channels, favors the inactivated state |
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Term
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Definition
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Term
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Definition
| Penetrate membrane when uncharged but bind in the charged state within the cell |
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Term
| Infected tissue presents problems... |
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Definition
| Tissue is acidic - alkaline anesthetics can't bind as well - DOSE HIGHER |
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Term
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Definition
smaller > larger
myelinated > not myelinated
Size > Myelin |
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Term
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Definition
| Pain, temperature, touch, pressure (last) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Inhibits NE reuptake, causes hypertension (unique in that sense) |
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Term
| Metabolism and excretion of esters |
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Definition
| short half life, rapidly broken down by plasma esterases (pseudocholinesterase) |
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Term
| Amides metabolism and excretion |
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Definition
| Metabolized by N-alkylation and p450; longer half life and higher systemic toxicity |
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Term
| Contraindication for lidocaine |
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Definition
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Term
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Definition
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Term
| Contraindications for epinephrine use |
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Definition
| Do not use in appendages due to lack of collateral blood flow |
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Term
| Short locals (20-45 minutes) |
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Definition
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Term
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Definition
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Term
| Medium-long duration (3-9 hours) |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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