-esterified estrogen and methyltestosterone

-Sex hormones

-treats vasomotor Sx of menopause (hotflashes)

-Raloxifene

-SERM

-Prevents/treats postmenopausal osteoporosis

-cholestryamine dec. [evista]

-Dec. Levothyroxine absorption

-Dec warfarin prothrombin time (10%)

-60mg qd...avoid in patients w/ history of thromboembolisms or prolonged immobility

-Dosogestral & Ethinyl estradiol

-prevents pregnancy/ovulation

-Combination of ethinyl estradiol and a type of progesterone (norethidrone, norgestimate, or levonorgestral)

-Increases effect of b-blockers/antidepressants

-Take pills at same time eachday/missed doses dec. effectiveness

-Norethidrone, Norgestimate, and Levonorgestral

-Prevents pregnancy, and moderate acne vulgaris (15 or older)

-Norethindrone/Progestin only oral contraceptive

-Prevents preg in 50% of users

-Decreased effectiveness if taken 3 or more hours late

-Methylprednisolone/glucocorticoids

-Treatment of acute asthma

-Many dosing options

Decadron

-Dexamethasone/glucocorticoids

-Variety of diseases, chronic swelling, diagnostic agent

-Sold in taper packs

-Levothyroxine sodium/thyroid hormone

-For hypothyroidism

-Estrogens decrease levothy. conc

-Inc. prothrombin time w/ warfarin

-cholestyramine impairs absorption

-take tabs 1/2 hr before meal in AM

-Report symptoms of toxicity (inc. pulse, chest pain)

-Ondansetron/5-HT₃ Receptor Antagonist

-Antiemetic. Used to prevent nausea and vomiting on cancer patients

-CYP450 inducers increase metabolism of zofran

-Enhanced hypotensive effect of apomorphine

-CHEMO IV: 32mg once before therapy

-Oral: 24mg 30 mins before therapy or 8mg before therapy, repeat in 8hrs. Then 8mg q 12h for 1-2days post therapy 

Ritalin, Concerta

C-II

-Methylphenidate/stimulant

-ADHD, narcolepsy/fatigue, tramatic brain injury

-Blocks reuptake of NE/DA

-Dont take with MAOI's or halogenated anesth.

-Take in AM before meal

-Long term use may stunt growth in kids

Provigil

C-IV

-Modafinil/stimulant

-Wakefulness, ADHD (mainly for narcolepsy)

-Dec. Effectiveness of oral contraceptives

-Tomaxifen/SERM

-Treatment/prevention of metastatic breast cancer

-CYP450

-Increas. effect of anti-coag.

-Dont breast feed/become pregnant

-Take same time daily

-Alendronate/Bisphosphonates

-Used for osteoporosis, Paget's disease

-Antacids decrease absorption

-Risk of GI irritation w/ aspirin/NSAIDs

-Ost. Treat=70mg qiw/or 10mg qd

-Ost. Prev=35mg qiw/or 5mg qd

-Dont lie down immediately after taking

Estrace

-Estradiol (estrogen)

-Vasomotor symptoms assoc. w/ menopause

-Barbiturates, rifampin, phenytoin, and carbamaz dec. estrogen levels

-Inc effect of cortico steroids

-Dont take if pregnant

-May cause weight gain, nausea/vomiting

-Estradiol Patch

-Dont place on breast

-Medroxyprogesterone (progestin)

-Abnormal menstruation/irregular vaginal bleeding

-Do not take if preg. or breast feeding

-MgOH/AlOH combo antacid

-Acid indigestion/Heartburn

-Neutralizes gastric salts, inactivates pepsin, and binds bile salts

-Dec. effects of tetracyclines

-Should not be taken for more than 2 weeks

-Separate from other meds by at least 2hrs

-Caution in renally impaired.

-CaCO₃

-Heartburn, Ca deficiency

-Same counseling as maalox

-Bismuth Subsalicylate or Bismuth Subgallate

-Antidiarrheal/ antisecretory agent

-Indigestion, diarrhea, ab cramps

-decreases abs. of tetra/doxycyline

-may darken tongue or stool

-Be careful w/ aspririn intolerant patients/kids (rye syndrome)

-Loperamide/antidiarrheal

-Inhibits peristalsis

-Notify dr. if diarrhea lasts longer than 48 hrs (may be a toxin)

-may cause dizziness/drowsiness

-4mg orally, followed by 2mg after each loose stool, MDD 16mg

-Simethicone/Antiflatuents

-Relief of bloating (Acts as surfactant)

-Take after meals and hs.

-Avoid carbonated beverages

Metamucil

-Psyllium/Bulk-forming laxative

-Dietary fiber supplement, treatment of constipation

-Causes water retention, increases fecal mass, causing peristalsis

-seperate other meds by at least one hour

-PEG 3350/ osmotic/hyperosmolar laxatives

-For constipation

-Mix 1 tbs in 8oz's of water, may take 2-4 days for a BM

-Do not take for more than 2 weeks

-Cimetidine/H₂ receptor antagonist

-Treatment of GERD/heartburn

-Inhibits gastric acid secretion via H2 receptor

-Increases toxicity of TCA's, Ca2+ blcokers, and SSRI's

-Decreases absorption of iron salts

-300-800mg qd-qid

-OTC: 200mg bid

30-60 mins before a meal

-Famotidine/H₂ receptor antagonist

-Treatment of GERD/heartburn

-Inhibits gastric acid secretion via H2 receptor

-Dec absorption of iron salts, antifungals, and some antivirals

-Do not use for more than 2 weeks w/o consulting Dr.

-take 15-60 mins befor meals

-Ranitidine/H₂ receptor antagonist

-Treatment of GERD/heartburn

-Inhibits gastric acid secretion via H2 receptor

-Increase toxicity of glipizide, theophylline, procainamide (at doses greater than 300mg)

-Dec. absorption of antifungals and aspirin

-Rx: 150 qd-qid or 300mg qd

-OTC: 75-150mg BID

-IV: 50mg q 6-8 hrs