Term
|
Definition
mAb
blocks IL-6 receptor ligand
rheumatoid arthritis |
|
|
Term
|
Definition
gene therapy
express p53 to promote apoptosis
head and neck cancer |
|
|
Term
|
Definition
gene therapy
express MHC class 1 complex
melanoma |
|
|
Term
|
Definition
ligand Fc fusion
CD2 ligand fused to Fc
chronic plaque psoriasis |
|
|
Term
|
Definition
double-stranded RNA
Toll-like receptor 3 activator
HIV, chronic fatigue syndrome |
|
|
Term
|
Definition
receptor Fc fusion
TACI receptor fused to Fc
systemic lupus |
|
|
Term
|
Definition
peptide
neutralize Blys (B-lymphocyte stimulator)
systemic lupus |
|
|
Term
|
Definition
vaccine
angiotensin II vaccine
hypertension |
|
|
Term
|
Definition
recombinant enzyme
replacement of beta-glucocerebrosidase
inherited lyposomal storage disease |
|
|
Term
|
Definition
mAb
neutralize TNF-alpha
rheumatoid arthritis |
|
|
Term
|
Definition
lipopolysaccharide analog
Toll-like receptor 4 activator
sepsis |
|
|
Term
|
Definition
antisense
blocks Bcl-2 to promote apoptosis
various cancers |
|
|
Term
|
Definition
mAb
neutralize IL-1 beta
Cryopyrin-associated Periodic Syndrome (CAPS) |
|
|
Term
|
Definition
peptide
block bradykinin production
Hereditary angioedema (HAE) |
|
|
Term
|
Definition
Fab fragment
block VEGF activity
wet age-related macular degeneration |
|
|
Term
|
Definition
aptamer
block VEGF activity
wet age-related macular degeneration |
|
|
Term
|
Definition
antisense
inhibit apolipoprotein B synthesis
high cholesterol |
|
|
Term
|
Definition
gene therapy
express cardiac enzyme
advanced heart failure |
|
|
Term
|
Definition
fusion
deliver toxin to CD-25 cells
T-cell lymphoma |
|
|
Term
|
Definition
mAb
suppress CD3 T-cells
type 1 diabetes |
|
|
Term
|
Definition
mAb
blocks HER2 dimerization
breast cancer |
|
|
Term
|
Definition
mAb
binds A-beta peptide for clearance
Alzheimer's disease |
|
|
Term
|
Definition
mAb
inhibits osteoclast formation
post-menopausal osteoporosis |
|
|
Term
|
Definition
cell therapy
autologous cellular immunotherapy
advanced prostate cancer |
|
|
Term
|
Definition
mAb
neutralizes IL-5
eosinophilic esophagitis |
|
|
Term
|
Definition
gene therapy
targeted expression to suppress cyclin 1
various cancers |
|
|
Term
|
Definition
mAb
neutralize TNF-alpha
psoriatic & rheumatoid arthritis |
|
|
Term
|
Definition
mAb
beta-amyloid
Alzheimer's disease |
|
|
Term
|
Definition
mAb
neutralize IL-12 & IL-23
plaque psoriasis |
|
|
Term
|
Definition
peptide
amylin replacement
Types 1 and 2 diabetes |
|
|
Term
|
Definition
vaccine
cocaine vaccine
cocaine addiction |
|
|
Term
|
Definition
mAb
neutralize nerve growth factor
chronic pain |
|
|
Term
|
Definition
mAb
phosphatidylserine
hepatitis C viral infection |
|
|
Term
|
Definition
mAb
block EGFR ligands
metastatic colorectal carcinoma |
|
|
Term
|
Definition
antisense
block VEGF activity
various cancers |
|
|
Term
|
Definition
mAb
block T-cell IL-2 receptor
transplant rejection |
|
|
