Term
| When are alleles "in coupling" |
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Definition
| When they are linked and on the same chromosome |
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Term
| When are alleles "in repulsion" |
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Definition
| When they are on opposite chromosomes |
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Term
| When to loci are farther apart, what does this do to their chance of recombination |
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Definition
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Term
| How is recombination frequency calculated? |
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Definition
| = (# recombinants) / (Total # offspring) |
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Term
| What is the maximum expected value for Recombination Frequency? |
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Definition
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Term
| Will a higher or lower recombination frequency indicate linkage between the marker and disease gene? |
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Definition
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Term
| a 0.2 recombination frequency is translated into what genetic distance (cM) |
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Definition
20 centiMorgans (each 1% RF corresponds to 1cM) |
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Term
| Regarding 2 loci, what does a LOD score > 1 suggest? |
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Definition
|
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Term
Regarding two loci, what does a LOD score < 1 suggest? |
|
Definition
| The two loci are unlinked |
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Term
| What LOD score is taken as proof of linkage? |
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Definition
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|
Term
| What LOD score is the threshold to consider 2 loci unlinked? |
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Definition
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