Term
| What is the MOA of linezolide? |
|
Definition
| Binds to the 23s portion of the 50s ribosomal subunit - inhibiting the initiation complex in bacterial translation systems |
|
|
Term
| What are the uses of Linezolides |
|
Definition
|
|
Term
| What are the ADR's of Linezolide? |
|
Definition
Thrombocytopenia
neutropenia
**esp in immunocompromised patients! |
|
|
Term
What are the drugs avaliable for VRSA?
|
|
Definition
Streptogramins (Quinupristin - Dalfopristin)
&
Linezolide |
|
|
Term
| Which antiboitic has an ADR of stevens-johnson syndrome? |
|
Definition
|
|
Term
| What is the DOC for Nocardia? |
|
Definition
|
|
Term
What drugs are available for treatment of P.caeinii?
which one is the DOC? |
|
Definition
Sulfonamides (DOC)
Clindomycin |
|
|
Term
| Which antibiotic is useful in the treatment of anaerobic bacteria? |
|
Definition
|
|
Term
Which antibiotic causes Grey baby syndrome?
why? |
|
Definition
| Chloramphenicol - lack of glucuronosyl transferase |
|
|
Term
What antibiotic causes Red man syndrome?
what causes it? |
|
Definition
| Vancomycin - due to histamine release |
|
|
